Glaucoma Therapeutics Market (2021 - 2031)
Glaucoma Therapeutics Market Report By Drug Class (Prostaglandins, Beta Blockers, Alpha Agonists, Carbonic, Anhydrase Inhibitors, Combination Medications, Cholinergic Medications), By End User (Hospitals, Ophthalmic Clinics, Ambulatory Surgical Centers) - Regional Forecast 2021 to 2031
Core Findings
FREE CustomizationGlaucoma Therapeutics Market Outlook
The glaucoma therapeutics market revenue will likely total US$ 6.6 Bn for 2021, according to Fact.MR. Overall, the market is expected to reach US$ 10 Bn by 2031, expanding 1.5x across the forthcoming decade. Demand for beta-blockers drug class will accelerate, anticipated to register a CAGR of 4.7% from 2021-2031.
Key Points Addressed in Glaucoma Therapeutics Industry Analysis
- Market Estimates and Forecasts (2016-2031)
- Key Drivers and Restraints Shaping Market Growth
- Segment-wise, Country-wise, and Region-wise Analysis
- Competition Mapping and Benchmarking
- Brand Share and Market Share Analysis
- Key Product Innovations and Regulatory Climate
- COVID-19 Impact on glaucoma therapeutics and How to Navigate
- Recommendation on Key Winning Strategies
Glaucoma Therapeutics Revenue Analysis from 2016 to 2020 vs Outlook 2021 to 2031
According to Fact.MR, a market research and competitive intelligence provider, from 2016 to 2020, the global market for glaucoma therapeutics has grown at a CAGR of almost 2.8%. Recent advancements in therapeutic interventions, such as the adoption of minimally invasive surgical techniques, have boded well for market growth in the said historical period.
Amid the COVID-19 pandemic, the industry experienced various fluctuations, with initial prospects appearing bleak. During the first quarter of 2020, exponentially rising infection cases prompted healthcare providers to relegate non-COVID-19 surgeries to the backyard. However, certain studies recorded an over 60% increase in emergency glaucoma care, particularly across developing countries such as India.
Throughout the pandemic, emergency surgeries in the country arose 4.3x, while more non-incisional procedures and less diagnostic testing were performed to minimize post-operative visits and viral load transmission. Future growth prospects are reliant on increased funding for clinical trials for discovering novel drugs, discovery of advanced surgical interventions and enhanced government support. Hence, the market is likely to surge at a CAGR of 4.2% from 2021-2031.
How is Open Angle Glaucoma Therapeutics Widening Growth Scope?
Globally, glaucoma is the leading cause of irreversible blindness, elevating the burden on existing healthcare frameworks. Primary open angle glaucoma (POAG) is the predominant subtype of glaucoma, with an estimated 52.68 million adults aged 40-80 suffering from it in 2020. This number is anticipated to reach nearly 80 million by 2040, with incidence in countries such as the U.S likely to reach 6.3 million.
Consequently, key healthcare and pharmaceutical stakeholders have directed voluminous finances to develop and fund research initiatives, clinical trials, drug development and awareness campaigns. Current treatment approaches include laser surgeries, incisional surgeries and oral medication.
Recently, since May 2021, a series of new glaucoma drug trials at the University of Minnesota. In collaboration with the Mayo Clinic, the research team at the Institute for Therapeutics Discovery & Development has developed the QLS-101, a novel prodrug of the KATP channel opener levcromakalim, designed to lower episcleral venous pressure in glaucoma patients. Phase I/II clinical trials have begun, which were licensed to Qlaris Bio in 2019.
Will Collaborative R&D Funding Yield Positive Outcomes for Market Growth?
Researchers are focusing on a pathway associated with inflammation, including Transforming Growth Factors β (TGFβ). In addition, they also study signaling molecules that communicate between cells and orchestrate fibrosis and inflammation. Moreover, clinical ophthalmologists generally prefer to use local therapies over systemic ones, since they are safer and more acceptable for patients. In addition, several patents from scientists have been filed for the use of shear-thinning fluid gels as eye drops that last for extended periods after administration, both alone or in combination with other therapeutics.
Furthermore, researchers have developed a method to combat glaucoma that replaces daily eye drops and surgery with twice-annual injections to maintain pressure in the eye. For instance, Glaucoma Research Foundation, a non-profit organization, received $1.5 million in donation for a collective vision restoration project. Additional fundraising would be provided to support organizations, such as the National Eye Institute, to finance interdisciplinary research projects. The initiative will be known as the Steven and Michele Kirsch Catalyst for a Cure Vision Restoration Initiative.
Country-wise Analysis
What Growth Prospects Abound for Glaucoma Therapeutics in North America?
More than 3 million Americans suffer from glaucoma. The majority of people with glaucoma do not exhibit any early symptoms. As a result, glaucoma therapeutics have grown in demand. In the United States, glaucoma accounts for somewhere between 50 and 70 percent of childhood glaucoma cases. It affects approximately one in every 10,000 infants under the age of four. This has led to high demand for glaucoma therapeutics in US markets.
It is estimated that 2.7% of Americans aged 40 and above are affected by open-angle glaucoma, thus creating a high demand for therapies on the market. About 3.3 million Americans age 40 and older are affected by blindness or low vision. In 2020, around 80 million individuals are estimated to have glaucoma globally, and it is expected that this number will reach over 111 million by 2040.
As a result of direct costs and productivity losses associated with glaucoma, the U.S. economy is losing more than $2.86 billion every year. There are over one million cases of glaucoma in the United States every year, with African Americans and Hispanics being the most affected in these regions. According to Fact.MR, around 30% of global revenue will be contributed by North America.
Europe to Emerge as a Pioneer in Open Angle Glaucoma Therapeutics?
In Western Europe, glaucoma appears to be the second most common reason for irreversible blindness, after age-related macular degradation. A study conducted worldwide observed that 2.93% of persons aged 40 to 80 years have glaucoma in these regions. A prevalence rate of 2.51% among those aged 40 to 80 is associated with open-angle glaucoma.
Additionally, in Germany, the majority of people suffer from open-angle glaucoma. The availability of surgical treatment for cataracts in industrialized countries has decreased the risk of acute angle-closure and narrow-angle glaucoma. The prevalence of open-angle glaucoma increases as one age, with 0.4% diagnosed in persons of European ancestry aged 40–44, with 2.7% in those aged 70–74, and 10.0% over 90. A market share worth 30% is anticipated by Fact.MR.
Laser treatment for glaucoma has recently been accepted as first-line therapy by the European Glaucoma Society (EGS), placing it on an equal footing with eye drops for treating the condition. Numerous laser manufacturers will be able to increase their penetration into the European market. The EGS guidelines aim to standardize practice within the European Union by providing recommendations for diagnosing and treating glaucoma.
How is Increasing Funding for Research Collaborations Enhancing Glaucoma Therapeutics in Asia?
Growing government funding in the medical industry has increased the market's demand for glaucoma drugs. As international firms continue to expand their operations there is a greater demand for glaucoma treatments. Fact.MR expects Asia to account for 25% of global revenue share in the market.
Increasing foray for advanced therapies, economic growth, and increased availability of drugs are leading to a higher demand for eye treatments in these regions. The number of people affected by POAG and PACG is expected to increase significantly in Asia by 2020. As a result, glaucoma cases in Asia are greater than in other regions. In addition, Asia will still have the highest number of PACG and POAG patients in 2040, with a growth of 18.8 million (79.8%) and 9.0 million (58.4%), respectively.
Chinese firm Arctic Vision announced a new research collaboration with the University of Hong Kong’s (HKU) Ophthalmology department intending to discover and develop new neuroprotective treatments for glaucoma. Through their alliance, Arctic Vision and HKU will search for new medications with a new mechanism of action for the treatment of glaucoma. The partners will focus on controlling mitochondrial activity as a neuroprotective approach for glaucoma and creating a microRNA-based gene treatment to protect the optic nerve in this patient population.
Category-wise Insights
Will Beta Blockers be the Primarily Consumed Glaucoma Therapeutics Drugs?
Patients are most likely to incline towards beta blockers, as they are relatively less expensive. To minimize the risk of systemic side effects. Combination medicines with beta blockers will grow at a CAGR of 4.7% during the forecast period.
Various blockers such as betaxolol, alpha-adrenergic agonists, carbonic anhydrase inhibitors, parasympathomimetics, epinephrine, and hyperosmotic agents are being used to treat glaucoma diseases in the medical field. Increasing demand for eye drops as treatment has grown demand for beta-blocker eye drops in the market.
Ophthalmic Clinics to Emerge as Primary Point of Contact for Availing Glaucoma Therapeutics?
A rise in glaucoma cases around the world has boosted the demand for treatments in ophthalmic clinics. A growing number of eye diseases and technological advances have strengthened the need for ophthalmic clinics within the medical industry. A CAGR of 4.5% is projected for the ophthalmic clinics segment by Fact.MR.
An aging population and the need for new treatment methods for patients, it has raised the demand for glaucoma therapeutics in ophthalmic clinics. For the management of chronic and acute eye diseases, innovative approaches must be employed to provide safe and sustainable services, which has led to an increase in the demand for therapeutics in ophthalmic clinics.
Competitive Landscape
Strategic collaborations enable manufacturers to increase production and meet consumer demand which will increase revenue and market share. New products and technologies will enable end-users to benefit from products that are eco-friendly by nature. Key developments in the market are as follows:
- In May 2020, the U.S Food & Drug Administration approved Allergan Plc.’s DURYSTATM (bimatoprost implant) New Drug Application. The drug is amongst the first intracameral, sustained-release implant indicated to reduce intraocular pressure (IOP) in patients with open-angle glaucoma, or ocular hypertension
- In October 2021, Novartis AG pledged to work with partners all around the world to help eliminate preventable visual impairment and blindness by reimagining access to eye care. The company has partnered with the International Agency for the Prevention of Blindness during the World Sight Day to initiate the #LoveYourEyes campaign
Report Scope
| Report Attributes | Details |
|---|---|
| Market Size Value in 2021 | USD 6.6 Billion |
| Market Value Forecast in 2031 | USD 10 Billion |
| Growth Rate | CAGR of 4.2% from 2021 to 2031 |
| Forecast Period | 2021 to 2031 |
| Historical Data Available for | 2016 to 2020 |
| Market Analysis | US$ Mn for Value & ‘000 Units for Volume |
| Key Regions Covered | North America; Europe; Asia Pacific; Latin America; Middle East & Africa |
| Key Countries Covered | U.S., Canada, Germany, U.K., France, Spain, Italy, China, Japan, India, Australia, New Zealand, Brazil, Mexico, GCC, South Africa |
| Key Segments Covered | Drug Class, End Users, Region |
| Key Companies Profiled | Allergan Plc.; Merck & Co. Inc.; Novartis AG; Pfizer Inc.; Santen Pharmaceuticals Co. Ltd.; Valeant Pharmaceuticals Inc.; Aerie Pharmaceuticals Inc. |
| Pricing | Available upon request |
Key Segments Covered
-
Drug Class :
- Prostaglandins
- Beta Blockers
- Alpha Agonists
- Carbonic Anhydrase Inhibitors
- Combination Medications
- Cholinergic Medications
-
End User :
- Hospitals
- Ophthalmic Clinics
- Ambulatory Surgical Centers
Table of Content
- 1. Preface
- 2. Assumptions and Research Methodology
- 3. Executive Summary: Global Market
- 4. Market Overview
- 5. Market Outlook
- 6. Global Market Analysis and Forecasts, by Drug Class
- 6.1. Prostaglandins
- 6.2. Beta Blockers
- 6.3. Alpha Agonists
- 6.4. Carbonic Anhydrase Inhibitors
- 6.5. Combination Medications
- 6.6. Cholinergics
- 7. Global Market Analysis and Forecasts, by End-user
- 7.1. Hospitals
- 7.2. Ophthalmic Clinics
- 7.3. Ambulatory Surgical Centers
- 8. Global Market Analysis and Forecasts, by Region
- 8.1. North America
- 8.2. Europe
- 8.3. Asia Pacific
- 8.4. Latin America
- 8.5. Middle East & Africa
- 9. North America Market Analysis and Forecast
- 10. Europe Market Analysis and Forecast
- 11. Asia Pacific Market Analysis and Forecast
- 12. Latin America Market Analysis and Forecast
- 13. Middle East & Africa Market Analysis and Forecast
- 14. Competition Landscape
- 14.1. Allergan plc
- 14.2. Merck & Co., Inc.
- 14.3. Novartis AG
- 14.4. Pfizer Inc.
- 14.5. Santen Pharmaceuticals Co. Ltd.
- 14.6. Valeant Pharmaceuticals International, Inc.
- 14.7. Aerie Pharmaceuticals Inc.
List Of Table
Table 01: Global Market Size (US$ Mn) Forecast, by Drug Class, 2021 to 2031
Table 02: Global Market Size (US$ Mn) Forecast, by End-user, 2021 to 2031
Table 03: Global Market Size (US$ Mn) Forecast, by Region, 2021 to 2031
Table 04: North America Market Value (US$ Mn) Forecast, by Drug Class, 2021 to 2031
Table 05: North America Market Forecast, by End-user, 2021 to 2031
Table 06: North America Market Value (US$ Mn) Forecast, by Country, 2021 to 2031
Table 07: U.S. Market Forecast, by Drug Class, 2021 to 2031
Table 08: U.S. Market Forecast, by End-user, 2021 to 2031
Table 09: Canada Market Forecast, by Drug Class, 2021 to 2031
Table 10: Canada Market Forecast, by End-user, 2021 to 2031
Table 11: Europe Market Value (US$ Mn) Forecast, by Drug Class, 2021 to 2031
Table 12: Europe Market Forecast, by End-user, 2021 to 2031
Table 13: Europe Market Value (US$ Mn) Forecast, by Country/Sub-region, 2021 to 2031
Table 14: U.K. Market Forecast, by Drug Class, 2021 to 2031
Table 15: U.K. Market Forecast, by End-user, 2021 to 2031
Table 16: Germany Market Forecast, by Drug Class, 2021 to 2031
Table 17: Germany Market Forecast, by End-user, 2021 to 2031
Table 18: France Market Forecast, by Drug Class, 2021 to 2031
Table 19: France Market Forecast, by End-user, 2021 to 2031
Table 20: Spain Market Forecast, by Drug Class, 2021 to 2031
Table 21: Spain Market Forecast, by End-user, 2021 to 2031
Table 22: Italy Market Forecast, by Drug Class, 2021 to 2031
Table 23: Italy Market Forecast, by End-user, 2021 to 2031
Table 24: Rest of Europe Market Forecast, by Drug Class, 2021 to 2031
Table 25: Rest of Europe Market Forecast, by End-user, 2021 to 2031
Table 26: Asia Pacific Market Value (US$ Mn) Forecast, by Drug Class, 2021 to 2031
Table 27: Asia Pacific Market Forecast, by End-user, 2021 to 2031
Table 28: Asia Pacific Market Value (US$ Mn) Forecast, by Country/Sub-region, 2021 to 2031
Table 29: Japan Market Forecast, by Drug Class, 2021 to 2031
Table 30: Japan Market Forecast, by End-user, 2021 to 2031
Table 31: China Market Forecast, by Drug Class, 2021 to 2031
Table 32: China Market Forecast, by End-user, 2021 to 2031
Table 33: India Market Forecast, by Drug Class, 2021 to 2031
Table 34: India Market Forecast, by End-user, 2021 to 2031
Table 35: Australia & New Zealand Market Forecast, by Drug Class, 2021 to 2031
Table 36: Australia & New Zealand Market Forecast, by End-user, 2021 to 2031
Table 37: Rest of APAC Market Forecast, by Drug Class, 2021 to 2031
Table 38: Rest of APAC Market Forecast, by End-user, 2021 to 2031
Table 39: Latin America Market Value (US$ Mn) Forecast, by Drug Class, 2021 to 2031
Table 40: Latin America Market Forecast, by End-user, 2021 to 2031
Table 41: Latin America Market Value (US$ Mn) Forecast, by Country/Sub-region, 2021 to 2031
Table 42: Brazil Market Forecast, by Drug Class, 2021 to 2031
Table 43: Brazil Market Forecast, by End-user, 2021 to 2031
Table 44: Mexico Market Forecast, by Drug Class, 2021 to 2031
Table 45: Mexico Market Forecast, by End-user, 2021 to 2031
Table 46: Rest of LATAM Market Forecast, by Drug Class, 2021 to 2031
Table 47: Rest of LATAM Market Forecast, by End-user, 2021 to 2031
Table 48: Middle East & Africa Market Value (US$ Mn) Forecast, by Drug Class, 2021 to 2031
Table 49: Middle East & Africa Market Forecast, by End-user, 2021 to 2031
Table 50: Middle East & Africa Market Value (US$ Mn) Forecast, by Country/Sub-region, 2021 to 2031
Table 51: GCC Countries Market Forecast, by Drug Class, 2021 to 2031
Table 52: GCC Countries Market Forecast, by End-user, 2021 to 2031
Table 53: South Africa Market Forecast, by Drug Class, 2021 to 2031
Table 54: South Africa Market Forecast, by End-user, 2021 to 2031
Table 55: Rest of MEA Market Forecast, by Drug Class, 2021 to 2031
Table 56: Rest of MEA Market Forecast, by End-user, 2021 to 2031
List Of Figures
Figure 01: Global Market Snapshot
Figure 02: Global Market Value (US$ Mn) Forecast and Y-o-Y Growth (%), 2021 to 2031
Figure 03: Market Value Share, by Drug Class (2020)
Figure 04: Market Value Share, by End-user (2020)
Figure 05: Market Value Share, by Region (2020)
Figure 06: Global Market Value Share Analysis, by Drug Class, 2021 and 2031
Figure 07: Global Prostaglandins Market Revenue (US$ Mn), 2021 to 2031
Figure 08: Global Beta Blockers Market Revenue (US$ Mn), 2021 to 2031
Figure 09: Global Alpha Agonist Market, Revenue (US$ Mn), 2021 to 2031
Figure 10: Global Carbonic Anhydrase Inhibitor (CAI) Market, Revenue (US$ Mn), 2021 to 2031
Figure 11: Global Combination Medications Market, Revenue (US$ Mn), 2021 to 2031
Figure 12: Global Cholinergic Market, Revenue (US$ Mn), 2021 to 2031
Figure 13: Global Market Attractiveness Analysis, by Drug Class
Figure 14: Global Market Value Share Analysis, by End-user, 2021 and 2031
Figure 15: Global Hospitals Market Revenue (US$ Mn), 2021 to 2031
Figure 16: Global Ophthalmic Clinics Market Revenue (US$ Mn), 2021 to 2031
Figure 17: Global Ambulatory Surgical Centers Market Revenue (US$ Mn), 2021 to 2031
Figure 18: Global Market Attractiveness Analysis, by End-user
Figure 19: Global Market Value Share Analysis, by Region, 2021 and 2031
Figure 20: Global Market Attractiveness Analysis, by Region, 2020 to 2031
Figure 21: North America Market Value (US$ Mn) Forecast, 2021 to 2031
Figure 22: North America Market Attractiveness Analysis, by Country
Figure 23: North America Market Value Share Analysis, by Drug Class, 2021 and 2031
Figure 24: North America Market Value Share Analysis, by End-user, 2021 and 2031
Figure 25: North America Market, by Country, 2021 and 2031
Figure 26: North America Market Attractiveness Analysis, by Drug Class
Figure 27: North America Market Attractiveness Analysis, by End-user
Figure 28: Europe Market Value (US$ Mn) Forecast, 2021 to 2031
Figure 29: Europe Market Attractiveness Analysis, by Country/Sub-Region
Figure 30: Europe Market Value Share Analysis, by Drug Class, 2021 and 2031
Figure 31: Europe Market Value Share Analysis, by End-user, 2021 and 2031
Figure 32: Europe Market, by Country/Sub-region
Figure 33: Europe Market Attractiveness Analysis, by Drug Class
Figure 34: Europe Market Attractiveness Analysis, by End-user
Figure 35: Asia Pacific Market Value (US$ Mn) Forecast, 2021 to 2031
Figure 36: Asia Pacific Market Attractiveness Analysis, by Country/Sub-Region
Figure 37: Asia Pacific Market Value Share Analysis, by Drug Class, 2021 and 2031
Figure 38: Asia Pacific Market Value Share Analysis, by End-user, 2021 and 2031
Figure 39: Asia Pacific Market, by Country/Sub-region
Figure 40: Asia Pacific Market Attractiveness Analysis, by Drug Class
Figure 41: Asia Pacific Market Attractiveness Analysis, by End-user
Figure 42: Latin America Market Value (US$ Mn) Forecast, 2021 to 2031
Figure 43: Latin America Market Attractiveness Analysis, by Country/Sub-region
Figure 44: Latin America Market Value Share Analysis, by Drug Class, 2021 and 2031
Figure 45: Latin America Market Value Share Analysis, by End-user, 2021 and 2031
Figure 46: North America Market, by Country/Sub-region
Figure 47: Latin America Market Attractiveness Analysis, by Drug Class
Figure 48: Latin America Market Attractiveness Analysis, by End-user
Figure 49: Middle East & Africa Market Value (US$ Mn) Forecast, 2021 to 2031
Figure 50: Middle East & Africa Market Attractiveness Analysis, by Country/Sub-region
Figure 51: Middle East & Africa Market Value Share Analysis, by Drug Class, 2021 and 2031
Figure 52: Middle East & Africa Market Value Share Analysis, by End-user, 2021 and 2031
Figure 53: Middle East & Africa Market, by Country/Sub-region
Figure 54: Middle East & Africa Market Attractiveness Analysis, by Drug Class
Figure 55: Middle East & Africa Market Attractiveness Analysis, by End-user
Figure 56: Global Market Share Analysis, by Company (2020)
- FAQs -
How much is the glaucoma therapeutics market worth?
The global glaucoma therapeutics market will be worth US$ 6.6 Bn by 2021-end
What was the last 5 years market CAGR
From 2016 to 2020, glaucoma therapeutics demand surged at a 2.8% CAGR
How much is the market likely to be valued by 2031?
The market for glaucoma therapeutics is expected to reach US$ 10 Bn by 2031
By how much is the global market for glaucoma therapeutics expected to surge?
From 2021-2031, the glaucoma therapeutics industry will register a CAGR of 4.2%
What are the key trends in glaucoma therapeutics in the global market?
New advanced treatments and drug delivery systems are augmenting demand for glaucoma therapeutics
Who are the top 5 players in the glaucoma therapeutics market?
Major market players include Allergan plc, Merck & Co., Inc., Novartis AG, Pfizer Inc., and Santen Pharmaceuticals Co.
How opportunistic are growth prospects across North America?
As per Fact.MR, North America will constitute 30% of global glaucoma therapeutics demand
What are the anticipated expansion prospects across Europe?
In Europe, glaucoma therapeutics will comprise 30% of the market share
Will Asia be an opportunistic market for glaucoma therapeutics?
Yes. Asia will likely yield a revenue share worth 25% in the global market for glaucoma therapeutics
Which drug category is likely to be the most consumed?
Beta blockers will likely emerge as the most consumed glaucoma therapeutic drugs, registering a 4.7% CAGR until 2031
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