Tangential Flow Filtration Market

Tangential Flow Filtration Market Outlook (2023 to 2033)

Newly-released tangential flow filtration market analysis report by Fact.MR reveals that global sales in the tangential flow filtration Market in 2022 were held at US$ 1.1 Billion. With 13% projected growth from 2023 to 2033, the market is expected to reach a valuation of US$ 4.2 Billion by the end of the forecast period.

Reusable systems are expected to be the highest revenue-generating product in the market, projected to grow at a CAGR of around 13% from 2023 to 2033.

Attributes	Details
Global Tangential Flow Filtration Market Size (2022)	US$ 1.1 Billion
Global Tangential Flow Filtration Market Size (2033)	US$ 4.2 Billion
Global Tangential Flow Filtration Market CAGR (2023 to 2033)	13%
U.S. Tangential Flow Filtration Market CAGR (2023 to 2033)	12. 8%
Key Companies Covered	Merck KGaA Danaher Corporation Sartorius AG Parker Hannifin Corporation Repligen Corporation Alfa Laval Andritz Meissner Filtration Products, Inc. Cole-Parmer Instrument Company Donaldson Company, Inc. Koch Separation Solutions Sterlitech Corporation Synder Filtration, Inc. Pendo Tech Microfilt India Pvt. Ltd.

Revenue of Tangential Flow Filtration Market from 2018 to 2022 Compared to Demand Outlook for 2023 to 2033

As per the research of the tangential flow filtration market by Fact.MR - a market research and competitive intelligence provider, historically, from 2018 to 2022, the market value increased at around 15% CAGR. With an absolute dollar opportunity of US$ 3 Billion, the market is projected to reach a valuation of US$ 4.2 Billion by 2033.

What are the Key Drivers Influencing the Market Expansion?

The key drivers influencing the market expansion include increasing demand for biopharmaceuticals, advancements in TFF technology, increasing adoption of single-use TFF systems, favorable government regulations, a growing biotechnology industry, and increasing demand for vaccines and antibodies.

Tangential flow filtration (TFF) is a separation technique that is commonly used in the biopharmaceutical industry for the purification and concentration of biomolecules such as proteins, DNA, and viruses. It is a type of membrane filtration that allows the selective passage of molecules based on their size, shape, and charge.

TFF is a cross-flow filtration technique where the sample flows tangentially across the surface of a semipermeable membrane under controlled conditions of pressure and flow rate. The driving force is the pressure gradient across the membrane, which causes the solvent and small molecules to pass through the membrane while retaining larger molecules such as proteins and viruses.

According to the International Diabetes Federation, around 463 million people between the age of 20 and 79 years were diagnosed with diabetes in 2019. Diabetic vaccines are playing an effective role in the prevention and treatment of diabetes. Tangential flow filtration is used for the purification, concentration, and clarification of vaccine components such as viral particles, proteins, and DNA. Due to the increase in cases of diabetes, the market is expected to surge.

Region-Wise Analysis

Which Region is Projected to Offer Significant Market Growth?

North America is a prominent shareholder in the market with a market size of US$ 452 million in 2022. It is projected that the region will have a market worth US$ 1.7 Billion by 2033.

According to the Canadian Cancer Society, an estimated 22 thousand Canadians were diagnosed with blood cancer in 2018. Leukemia is the most common type of blood cancer in Canada; with over 6 thousand cases diagnosed in 2018. Tangential flow filtration (TFF) is a key technique used in the research and treatment of blood malignancies, such as leukemia, lymphoma, and myeloma.

This technique is used to isolate, concentrate, and purify a variety of biological components, such as proteins, nucleic acids, and viruses, which are crucial to the pathogenesis and development of blood malignancies. The increase in various types of cancer is expected to impact the market growth.

Country-Wise Analysis

United States Tangential Flow Filtration Market Analysis :

The market is expected to grow to be worth US$ 1.5 Billion by 2033, with an absolute dollar growth of US$ 1 Billion from 2023 to 2033. The market in the United States has grown at a CAGR of 14.9% from 2018 to 2022 and is expected to grow at a CAGR of 12.8% from 2023 to 2033.

According to World Health Organization, in 2020, around 19.5 million cases of Covid-19 were diagnosed while over 1.6 million deaths were reported in the United States. The virus quickly spread throughout the country which led to the surge in demand for biopharmaceuticals. Tangential flow filtration (TFF) has been used extensively during the Covid-19 pandemic for various applications, including the production and purification of vaccines, antibodies, and other biologics. The increase in demand for medications for COVID-19 led to market growth.

United Kingdom Tangential Flow Filtration Market Analysis :

The market in the United Kingdom is expected to grow to be worth US$ 208.5 million by 2033, with an absolute dollar growth of US$ 142.3 million. The market in the United Kingdom has grown at a CAGR of 13.9% from 2018 to 2022 and is expected to grow at a CAGR of 12.1% from 2023 to 2033.

The UK government had invested over US$ 230 million in COVID-19 vaccine research through a vaccine task force. This investment has helped to support the development of several vaccine candidates, including the Pfizer, BioNTech, Oxford, AstraZeneca, and Moderna vaccines. Tangential flow filtration is used for the purification, development, and manufacturing of biological drugs, vaccines, and other biopharmaceutical products. This is expected to impact the market growth.

China Tangential Flow Filtration Market Analysis :

In China, the market is expected to grow to be worth US$ 301.4 million with an absolute dollar growth of US$ 207.3 million. The market in China has grown at a CAGR of 14.4% from 2018 to 2022 and is expected to grow at a CAGR of 12.3% from 2023 to 2033.

China's COVID-19 vaccine industry has attracted significant attention and investment from both domestic and foreign venture capital firms. Some of the key players in this industry include Sinopharm, Sinovac, CanSino Biologics, and Walvax Biotechnology, among others.

According to research, Chinese vaccine makers have raised a total of US$ 3.5 billion in venture capital and private equity funding in 2021. Some of the notable investors in this space include Hillhouse Capital, Sequoia Capital China, Qiming Venture Partners, and IDG Capital, among others. The increase in venture capital, investment, and funding from the government influences the growth of the tangential filtration market.

Japan Tangential Flow Filtration Market Analysis :

In Japan, the market is expected to grow to be worth US$ 169.1 million with an absolute dollar growth of US$ 108.3 million. The market in Japan has grown at a CAGR of 12.2% from 2018 to 2022 and is expected to grow at a CAGR of 10.8% from 2023 to 2033.

According to research, in 2018, over 760 thousand rheumatoid arthritis cases were diagnosed in Japan. This is one of the common types of inflammatory arthritis which affects people of all ages. Tangential flow filtration is used for the manufacturing of biological drugs for the treatment of rheumatoid arthritis. This influences the market growth for tangential filtration.

India Tangential Flow Filtration Market Analysis :

The market in India is expected to grow to be worth US$ 92.7 million by 2033, with an absolute dollar growth of US$ 57.1 million. The market in the country has grown at a CAGR of 11.2% from 2018 to 2022 and is expected to grow at a CAGR of 10% from 2023 to 2033.

According to research, in 2018, about 67 thousand cases of lung cancer were diagnosed and around 63 thousand deaths were reported in India. Lung cancer was the leading cause of death in the country. Tangential flow filtration has been used in the purification of monoclonal antibodies (mAbs) that are used to treat lung cancer. The increase in demand for tangential flow filtration influences market growth.

Category-Wise Insights

Through Which Product Is the Market Projected to Witness Significant Growth?

The market through reusable systems is projected to witness significant growth with a CAGR of 15.2% from 2018 to 2022 and is expected to grow at a CAGR of 12.8% from 2023 to 2033.

Reusable systems are designed to be used multiple times, rather than being intended for single use or disposal. These systems are often used in industries such as healthcare, laboratory research, and manufacturing, where the production of waste can be costly, environmentally damaging, or pose a risk to human health. Reusable systems can offer several benefits, such as reducing waste, lowering costs, and improving sustainability.

Which End User in the Market is Projected to Witness the Significant Growth?

Pharmaceutical & Biotechnology Companies are projected to witness significant growth with a CAGR of 14.8% from 2018 to 2022 and are expected to grow at a CAGR of 12.6% from 2023 to 2033.

Tangential flow filtration is a critical tool in the development and production of biological drugs, as it allows for the efficient purification and concentration of these complex molecules, helping to ensure their safety and efficacy for patients. It is also used in the development and production of a wide range of biological drugs, including monoclonal antibodies, vaccines, gene therapies, and cell therapies. The technique is also used in the production of viral vectors, which are used in gene therapy approaches.

Competitive Analysis

Key players in the market are Merck KGaA, Danaher Corporation, Sartorius AG, Parker Hannifin Corporation, Repligen Corporation, Alfa Laval, Andritz, Meissner Filtration Products, Inc., Cole-Parmer Instrument Company, Donaldson Company, Inc, Koch Separation Solutions, Sterlitech Corporation, Synder Filtration, Inc., Pendo Tech, and Microfilt India Pvt. Ltd.

A few of the recent developments in the market are :

• In January 2021: Pall Corporation invested a total of US$ 114 million to fulfill the rising demand for single-use technologies required for the production of the COVID-19 vaccine.
• In March 2021: The joint venture between Pall and Austar, Pall-Austar Lifesciences Ltd. has completed a shareholding acquisition by Pall Corporation, an operational company within Danaher Corporation's Life Sciences platform for filtration, separation, and purification technologies. This acquisition will increase production capacity to primarily satisfy China's COVID-19-driven need for single-use technology supply chains.
• In August 2020, Agidens Process Automation collaborated with Parker Hannifin for the expansion of the Parker Bioscience filtration division.

Segmentation of the Tangential Flow Filtration Market

• By Product :

  • Single-Use Systems
  • Reusable Systems
  • Membrane Filters
  • Filtration Accessories

• By Membrane Material :

  • Polyethersulfone
  • Polyvinylidene Difluoride
  • Nylon
  • Polytetrafluoroethylene
  • Mixed Cellulose Ester & Cellulose Acetate
  • Polycarbonate Tracked Etched
  • Regenerated Cellulose
  • Other Membrane Materials

• By Technique :

  • Microfiltration
  • Ultrafiltration
  • Nanofiltration
  • Other Techniques

• By Application :

  • API Filtration
  • Protein Purification
  • Vaccine and Antibody Processing
  • Formulation and Filling Solutions
  • Viral Clearance
  • Media Buffer Filtration
  • Cell Separation
  • Water Purification
  • Air Purification

• By End User :

  • Pharmaceutical and Biotechnology Companies
  • CMOs & CROs
  • Academic Institutes & Research Laboratories

• By Region :

  • North America
  • Latin America
  • Europe
  • Asia Pacific
  • Middle East & Africa