Pepsin Market

Pepsin Market Outlook

Pepsin market value is anticipated to increase at a CAGR 4.7% over the forecast period of 2021 to 2031, and is set to surpass a valuation of US$ 4.8 Bn by 2031, as per Fact.MR’s detailed industry analysis. In 2020, the market enjoyed a valuation of US$ 2.9 Bn, which is equivalent to 30% of the global enzymes market.

Pepsin Market Size (2021)	USD 3 Bn
Market Forecasted Value (2031)	USD 4.8 Bn
Global Growth Rate	CAGR 4.7%
Europe Market Share	One-third

Pepsin is a naturally occurring digestive protein found in the highly acidic environment of the stomach. For commercial applications, pepsin is used extensively as a digestive enzyme supplement in the pharmaceutical industry.

Of the end-use industries considered, consumption of pepsin can be significantly observed in pharmaceuticals, which accounts for nearly 50% of overall pepsin demand, owing to extensive utilization in the manufacture of lifesaving drugs.

Demand Analysis of Pepsin from 2016 to 2020 Vs Market Outlook for 2021 to 2031

Over the 2016-2020 historical period, the pepsin market expanded at 2.9% CAGR, on the back of high pepsin adoption as an intermediate in digestive drugs and as a protein supplement, as per Fact.MR - a market research and competitive intelligence provider. In digestive drugs, pepsin is used as a degrading or proteolytic enzyme that directly impacts the digestive system.

Rising application of pepsin, which is an endopeptidase, in the pharmaceutical industry, was one of the prominent factors for the growth of pepsin sales during 2016-2020. In terms of value, pepsin revenue generated by the pharmaceutical industry reached US$ 1.45 Bn in 2020. Considering the forecast period of 2021-2031, the pharmaceutical industry is anticipated to witness substantial growth, which provides a positive outlook for pepsin manufacturers.

Additionally, application of pepsin in the industrial sector is increasing so as to remove unwanted remaining tissue from partially processed hide in leather. Furthermore, pepsin is applied during silver recovery from discarded photographic films by digesting the gelatin layer that holds the silver.

All these application have been identified as niche applications of pepsin that are expected to witness steady growth over the coming years.

Below points summarize the market over the long-run forecast period:

• Pharmaceutical industry is a prominent consumer of pepsin accounting for over 50% market share in 2020.
• Application of pepsin in the industrial sector is anticipated to increase at a steady pace over the decade.
• China is the centre of attraction for pepsin manufacturers as the country has a robust pharmaceutical sector.
• Application of pepsin in food & feed is anticipated to increase at a CAGR 2.5% during 2016-2020.

What are the Prospects for Pepsin as a Food Additive?

Demand for pepsin as a food additive has significantly risen in the past half- decade. For instance, pepsin is commercially used in the processing of soy protein and gelatin. Moreover, pepsin is also used in applications ranging from poultry, meat, and cream novelties such as ice cream, nutritional beverages, and dairy products.

In addition, pepsin is used as a substitute for rennin in the production of cheese. Rise in demand for cheese and ease of production of the same with pre-integrated processes, including pepsin, will bolster pepsin demand over the long-run forecast period.

Country-wise Analysis

Why is the German Market for Pepsin Significant?

From a regional perspective, Europe accounts for around 1/3 market share in the global pepsin market. Germany has been identified for its consistent growth in the pharmaceutical industry, and has provided potential market opportunities.

BIOZYM is responsible for developing and producing pepsin at a high volume in the country.  Both, in terms of production and consumption, Europe is considered as a sizeable market for pepsin, anticipated to reach US$ 351 Mn by 2031-end.

Why is the Pepsin Business in China Anticipated to Grow Much Faster Than the Global Average?

APEJ is one of the lucrative markets for pepsin in terms of consumption. China is at the forefront of demand with robust pharmaceutical production in the region, accounting for bulk of the demand for pepsin.

Consumption of pepsin in emerging countries such as China, India, Malaysia, and Thailand is likely to increase rapidly in line with population growth. This is because downstream applications of pepsin are concentrated in pharmaceuticals and health supplement products.

In terms of value, the pepsin market in China is anticipated to expand at a CAGR of 5.5% through 2031.

Category-wise Analysis

How is the Growing Pharmaceutical Industry Triggering Pepsin Requirement?

Pepsins held great significance in the pharmaceutical industry over the past half-decade. Although limited companies specialize in the production of pepsin, demand for the same for pharmaceutical applications is burgeoning at a faster pace, providing an upward thrust to pepsin price points.

Pepsin is a prominent precursor used in the formulation of protein supplements, specialized for patients with anaemic conditions. Apart from protein supplements, pepsin is also used to produce appetite enhancers. Collectively, these applications of pepsin will provide strong demand growth over the coming years.

Globally, the pharmaceutical industry is a prominent consumer of pepsin, which accounts for over 50% of pepsin produced globally. Pepsin utilization for pancreatic insufficiency holds a significant market share in terms of value.

Which Form of Pepsin Witnesses High Demand?

Ease of storage and logistics of powder pepsin over liquid pepsin, or pepsin syrup, has attracted industry giants in the pharmaceutical and food & beverage industry over the past half-decade, and this has provided an impetus strengthening the positive network externalities across the industry.

In the food industry, milk protein hydrolysates are manufactured utilizing pepsin powder, which is further used in flavouring food, functional beverages, and vegetable processing. Moreover, pepsin powder is also used to prepare fab fragments.

On the grounds of the aforementioned factors, pepsin in the powder form captured 69% of global demand in 2020. This share is anticipated to rise further over the coming years.

Competitive landscape

Competitive landscape reveals that the top manufacturers of pepsin include Biolaxi Corporation, A. Constantino & C., BIOZYM, Chongqing Jingkang Biotechnology, Deyang Sinozyme, Chongqing quanxinxiangsheng, and Enzymology Research Center.

The market sees sizable demand from the pharmaceutical industry, and to meet this demand, manufacturers have expanded their production capacities.

Report Scope

Attribute	Details
Forecast Period	2021-2031
Historical Data Available for	2016-2020
Market Analysis	Value in US$ Mn, Volume in KT
Key Regions Covered	North America Latin America Europe Japan APEJ Middle East Africa
Key Countries Covered	U.S. Canada Mexico Brazil Argentina Germany Italy Spain Italy Portugal China Japan India Taiwan Indonesia GCC Countries South Africa Turkey
Key Market Segments Covered	By Product Form By End Use Sector By Grade Type Region
Key Companies Profiled	A. Constantino & C. Biolaxi Corporation BIOZYM Chongqing quanxinxiangsheng Chongqing Jingkang Biotechnology Deyang Sinozyme Enzymology Research Center
Pricing	Available upon Request

Key Segments Covered in Pepsin Industry Research

• By Product Form

  • Powdered Pepsin
  • Liquid Pepsin

• By End-use Sector

  • Pepsin for Pharmaceuticals
  • Industrial Pepsin
  • Pepsin for Food and Feed
  • Others

• By Grade Type

  • 1:3,000 Pepsin
  • 1:10,000 Pepsin
  • 1:15,000 Pepsin