Tissue Glue and Bio-adhesive Sealant Market

Tissue Glue and Bio-adhesive Sealant Market Study by Protein-based, Collagen-based, Thrombin-based, Fibrin, and Gelatin-based Sealants from 2024 to 2034

Analysis of Tissue Glue and Bio-adhesive Sealant Market Covering 30+ Countries Including Analysis of US, Canada, UK, Germany, France, Nordics, GCC countries, Japan, Korea and many more

Tissue Glue and Bio-adhesive Sealant Market Outlook (2024 to 2034)

As per the latest industry analysis done by skilled analysts at Fact.MR, the global tissue glue and bio-adhesive sealant market size is poised to reach a size of US$ 2.28 billion in 2024 and thereafter expand at a CAGR of 8% to increase to US$ 4.91 billion by 2034-end.

Demand for tissue glue and bio-adhesive sealants is rising due to their effective use in various applications such as graft attachment, and colon, vascular, and lung sealing. These adhesives also serve as structural filters or tissue scaffolding, replacing or complementing sutures and donor transplant materials, thus driving tissue glue and bio-adhesive sealant market growth.

Primarily utilized on external wounds, tissue glue can be used alone or with stitches or adhesive tapes. It forms a protective waterproof covering. Suppliers focus on external wound applications and adjust production techniques to occupy a significant market share.

Cyanoacrylates are an early component in tissue glue manufacturing that facilitates surface connection and prevents substrate separation. This property attracts end users looking for pain-free, faster wound healing. This is contributing to the expansion of the tissue glue and bio-adhesive sealant market size.

Advantages such as easy and rapid application without follow-ups for residual component removal are contributing to the adoption of tissue glue and bio-adhesive sealants. Recent innovations such as synthetic and semi-synthetic adhesives with biomimetic characteristics and superior biocompatibility cater to various age groups.

Tissue adhesives like histoacryl and bucrylate are effective in treating variceal bleeding, offering fast, easy settlement with significant success rates. As people seek faster healing methods, the market continues to grow. Manufacturers are investing in better understanding of research to understand human skin and are focusing on upgrading techniques to align with medical advancements. This investment promotes market competitiveness and contributes to the expansion of the tissue glue and bio-adhesive sealant market.

Report Attributes Details
Tissue Glue and Bio-adhesive Sealant Market Size (2024E) US$ 2.28 Billion
Forecasted Market Value (2034F) US$ 4.91 Billion
Global Market Growth Rate (2024 to 2034) 8% CAGR
Canada Market Growth Rate (2024 to 2034) 8.5% CAGR
China Market Value (2034F) US$ 300 Million
North America Market Share (2024E) 54.8%
East Asia Market Share (2034F) 17.3%
Key Companies Profiled
  • CryoLife
  • Baxter International Inc.
  • Luna Innovations Incorporated
  • Dentsply Sirona Inc.
  • Choera Medical Inc.
  • Integra Life Sciences Corporation
  • Stryker Corporation
  • Tricol Biomedical Inc.
  • Johnson and Johnson

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Which Tissue Glue and Bio-adhesive Sealant Market Trends are Producers Leveraging?

“Increasing Prevalence of Bone-related Disorders Boosting Demand for Tissue Adhesives”

The market for tissue glue and bio-adhesive sealants is expanding as a result of factors including the rise in arthroplasty surgeries and the frequency of bone-related illnesses. Market expansion is projected to be hampered, although, by factors including the underutilization of tissue glue and bio-adhesive sealants in developing nations as a result of ignorance about their advantages, clinical efficacy, safety, and affordability. Despite challenges, the market is projected to grow as medical advances progress steadily.

“Role of Bio-adhesives in Preventing Bleeding During Surgery”

Owing to their effectiveness in stopping bleeding during surgery, tissue sealants and tissue adhesive solutions are becoming more and more popular among surgeons, which is driving market growth. These tissue sealants reduce bleeding that occurs after surgery. Furthermore, these tissue sealants are very simple to apply, very effective, and less likely to become infected with microorganisms following surgery.

This enhances the success rates of surgeries, thus helping in preventing any loss of access to blood during surgeries. In complex surgeries, bio-adhesives are crucial for preventing potential loss of life. These factors are driving the desirability of bio-adhesives, leading to increased sales and profits in the market.

What are the Hindrances to Market Growth?

“Restricted Application Potential of Tissue Glue and Need for Heavy Investments in Production”

One of the significant setbacks with tissue glue is that it cannot be applied to any type of internal wound, thus significantly impacting the profits and the overall trajectory of the market. Bio-adhesives are not recommended for use in conditions such as infected wounds, high-tension areas, edematous wound edges, skin loss, animal bites, mucosal surfaces, mucocutaneous junctions, or patients with a risk of delayed wound healing. All these factors further limit market growth and create a negative impression among end-users about the products.

Despite these challenges, key players in the market are actively investing resources and strategically exploring solutions to overcome these obstacles. They aim to establish their foothold in the market through innovative approaches and continuous improvement initiatives.

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The global medical industry is exhibiting steady growth, driven by significant advancements in medical techniques aimed at enhancing patient health. Each country is investing in its medical sector to cultivate a skilled workforce and bolster national assets. Tissue glue and bio-adhesive sealants are notable innovations that have transformed the medical landscape in countries like the United States, Canada, China, Japan, and South Korea. Among all these countries, the Japanese market is projected to expand at a CAGR of 9% from 2024 to 2034.

What are the Opportunities for Tissue Glue and Bio-adhesive Suppliers in the United States?

“Greater Awareness Among Patients and Physicians about Available Treatment Options”

Attribute United States
Market Value (2024E) US$ 1.03 Billion
Growth Rate (2024 to 2034) 8.3% CAGR
Projected Value (2034F) US$ 2.28 Billion

Growing population, longer life expectancies, and greater patient and physician awareness of available treatment options are projected to contribute to the growing demand for tissue sealants and tissue adhesives during the forecast period in the United States. New investments in cutting-edge medical research facilities and healthcare infrastructure are also playing a major role in this market.

The United States has gained a solid reputation in the market due to these factors, prompting suppliers to actively seek opportunities to establish their presence in other regions. Suppliers are willing to invest in understanding market needs and setting up efficient supply chains to capitalize on the immense market potential.

How is Innovation Driving Market Expansion in China?

“Adoption of High-Quality Medical Practices Driving Tissue Glue and Bio-adhesive Demand”

Attribute China
Market Value (2024E) US$ 131 Million
Growth Rate (2024 to 2034) 8.6% CAGR
Projected Value (2034F) US$ 300 Million

China has some of the world's top hospitals and surgeons, employing cutting-edge medical practices to ensure swift recoveries. Therefore, the demand for tissue glues in Chinese hospitals has risen substantially in recent years, with projections of continued growth. Manufacturers keenly grasp surgeons' needs and are projected to seize this opportunity to expand their market share and establish dominance. This trend underscores the importance of innovation and responsiveness to medical experts’ evolving needs in the competitive healthcare landscape.

Category-wise Insights

According to this unveiled report from Fact.MR, a market intelligence company, the specialty clinics segment is projected to expand at a CAGR of 7.3% from 2024 to 2034.

Why are Tissue Glue and Bio-adhesive Sealants Extensively Used in Hospitals?

“High Volume of Patients with Skin Wounds”

Attribute Hospitals
Segment Value (2024E) US$ 1.63 Billion
Growth Rate (2024 to 2034) 8.2% CAGR
Projected Value (2034F) US$ 3.57 Billion

Hospitals witness frequent influx of patients suffering from skin wounds and therefore occupy a significant tissue glue and bio-adhesive sealant market share. Market suppliers strategically assess demand across hospitals, tailoring their approaches accordingly. With multiple departments and diverse medical professionals collaborating within hospitals, the demand for tissue glue and bio-adhesive sealants is further rising worldwide.

Tissue glue and bio-adhesive sealants are extensively used in hospitals due to their effectiveness in sealing wounds quickly, reducing bleeding, and promoting faster healing. They provide a convenient and efficient alternative to conventional sutures or staples, especially in cases where stitches are challenging to apply. These adhesives are versatile and can be applied to various types of wounds, contributing to their widespread usage in hospital settings.

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Market Competition

Key players in the tissue glue and bio-adhesive sealant market have been focusing on the creation of more advanced tissue glue and bio-adhesive sealants in recent years to cater to a variety of clientele, including children and elderly patients. Surgical sealants play a crucial role in healthcare by preventing cross-contamination and transmission of infections while protecting delicate skin from damage during medical procedures.

The tissue glue and bio-adhesive sealant market is characterized by the emergence of innovative products like bone glue and gelatin bone glue. These advancements address specific needs in orthopedic and reconstructive surgeries and offer effective solutions for bone repair and reconstruction. As a result, the evolving landscape of surgical sealants reflects the ongoing innovation and adaptation within the medical field to meet diverse clinical requirements.

  • Newly launched products like TissueGlue skin adhesive by CryoLife, CoSeal by Baxter, and DERMABOND ADVANCED® Topical Skin Adhesive by Ethicon Inc. are regarded as technological breakthroughs in the global tissue glue and bio-adhesive sealant market.

Key Segments of Tissue Glue and Bio-adhesive Sealant Market Research

  • By Product Type :

    • Protein-based Sealants
    • Collagen-based Sealants
    • Thrombin-based Sealants
    • Fibrin Sealants
    • Gelatin-based Sealants
  • By Application :

    • Cardiovascular Surgeries
    • Laparoscopic Surgeries
    • Burns & Skin Grafting
    • Digestive Surgeries
    • Cosmetic, Reconstructive, & Hand Surgeries
    • General Surgeries
  • By End User :

    • Hospitals
    • Specialty Clinics
    • ASCs
  • By Region :

    • North America
    • Latin America
    • Europe
    • East Asia
    • South Asia & Oceania
    • Middle East & Africa

- FAQs -

How big is the tissue glue and bio-adhesive sealant market size in 2024?

The global market for tissue glue and bio-adhesive sealant stands at US$ 2.28 billion in 2024.

What is the projected revenue from tissue glue and bio-adhesive sealant sales for 2034?

By 2034, worldwide revenue from tissue glue and bio-adhesive sealant sales is projected to reach US$ 4.91 billion.

How fast is this market projected to increase over the decade?

The global market has been forecasted to increase at 8% CAGR through 2034.

What is the sales forecast for tissue glue and bio-adhesive sealants in North America?

Tissue glue and bio-adhesive sealant sales in North America are forecasted to increase at 8.3% CAGR from 2024 to 2034.

At what rate is the market projected to expand in East Asia?

The market in East Asia is projected to expand at a CAGR of 8.7% from 2024 to 2034.

At what rate are product sales forecasted to rise in Japan?

The market in Japan has been forecasted to rise at a CAGR of 9% from 2024 to 2034.

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Tissue Glue and Bio-adhesive Sealant Market

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