Knee Cartilage Repair Market

Knee Cartilage Repair Market Analysis By Treatment Modality (Arthroscopic Chondroplasty, Autologous Chondrocyte Implantation, Implants Transplant, Others), By Cartilage Type (Fibrocartilage & Hyaline Cartilage) By End-User and By Region – Global Market Insights 2022 to 2027

Analysis of Knee Cartilage Repair market covering 30 + countries including analysis of US, Canada, UK, Germany, France, Nordics, GCC countries, Japan, Korea and many more

Knee Cartilage Repair Market Outlook (2022-2027)

The global knee cartilage repair market is predicted to evolve at a CAGR of 5% from 2022 to 2027. In 2022, the market stands at a valuation of US$ 3.92 billion and is expected to reach US$ 5 billion by the end of 2027.

The U.S., China, and Canada are expected to be highly lucrative markets for knee cartilage repair over the next five years.

Report Attributes


Market Size (2022)

US$ 3.92 Billion

Projected Market Value (2027)

US$ 5 Billion

Global Market Growth Rate (2022-2027)


Market Share of Arthroscopic Chondroplasty


Key Companies Profiled

  • TiGenix NV
  • ISTO Biologics
  • Vericel Corporation
  • B. Braun Melsungen AG
  • Zimmer Biomet Holdings, Inc.
  • DePuy Synthes
  • Osiris Therapeutics, Inc.
  • Smith & Nephew PLC
  • Histogenics Corporation
  • Stryker Corporation

Know thy Competitors

Competitive landscape highlights only certain players
Complete list available upon request

Demand Analysis of Knee Cartilage Repair (2017-2021) Vs. Market Outlook (2022-2027)

“Increasing Prevalence of Osteoarthritis & Orthopedic Injuries Driving Market Expansion”

According to Fact.MR, a market research and competitive intelligence provider, the knee cartilage repair market, is expected to increase at a CAGR of 5% from 2022 to 2027.

Several parts of the body include cartilage, a supple, flexible substance that acts as connective tissue. A thin and flexible substance called knee cartilage binds the bones of the knee joints together and lessens friction between them. The cartilage in the knee, however, can be damaged by strenuous sports, hereditary flaws, and hormone imbalances.

In the process of repairing damaged cartilage in the knee, the remaining surface of the tissue is also smoothed. Bone ends are shielded by cartilage, which also helps joints move smoothly. The diagnosis of damaged knee cartilage is made through clinical examination and medical imaging.

Common cartilage injuries include those to the bottom of the femur and the rear of the kneecap. Knee cartilage restoration may be beneficial for patients with congenital defects, hormone imbalances, sports injuries, or trauma.

The market is being driven by the rising prevalence of joint and bone problems, an ageing population, and a growing number of sports-related injuries & road accidents. The prevalence of osteoarthritis and orthopedic injuries is anticipated to expand the cartilage surgery industry size over the coming years.

Knee cartilage repair market forecast by Fact.MR

What’s Majorly Driving Knee Cartilage Repair Market Growth?

“Constant Technological Advancements in Knee Cartilage Repair Procedures”

The obesity problem has increased the chances of knee cartilage degradation, which is anticipated to drive market growth. Due to the incidence of head injuries sustained while participating in sports activities such as cycling, skating, or skateboarding, the market for knee cartilage repair is growing.

Due to technological advancements that improve the treatment for knee cartilage damage, the market for knee cartilage restoration offers higher economic potential. Additionally, cartilage has a low blood supply compared to other human tissues, which limits its ability to support or heal donor cartilage. It is a form of connective tissue that is found all over the body but is more common in joints.

Since meniscus tissue deterioration affects a large number of people worldwide, major firms are making significant investments to develop better ways for cartilage regeneration and repair. Recent advances in 3D technology allow researchers to use specialized bio-inks to bio-print a 3D hybrid tissue for mending cartilage. These inks make use of hydrogels to create a unique formulation that provides a hospitable milieu for cells while preserving structural integrity.

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What are the Challenging Factors for Market Expansion?

“Dearth of Trained Professionals & High Cost Associated with Surgeries”

The lack of qualified surgeons for executing knee cartilage repair procedures in developed and developing nations, as well as stringent regulatory restrictions for the licensing of scaffolds, are the two main reasons that may restrain the growth of the joint cartilage repair market.

The market revenue growth might be constrained by the high cost of cartilage repair procedures. The high cost of knee cartilage replacement surgery may deter patients from undertaking knee cartilage repair procedures, leading them to choose less invasive, less costly treatments such as muscle-strengthening procedures that enhance knee stabilization.

What Techniques are New Companies Using to Thrive in the Knee Cartilage Repair Industry?

“Introduction of Innovative Products and High-end Treatment Options Making Way for Start-ups”

New entrants are focusing on improved cartilage repair and restoration procedures and also offering high-end treatment options for joint issues. Innovations are being implemented by new companies to produce effective products that will offer positive clinical outcomes.

  • Cartilage Inc. a start-up based in the U.S., develops solutions for cartilage regeneration to reduce the need for further therapies and enhance patient quality of life. It creates products to repair both, little and significant cartilage abnormalities, using technologies created at the University of California, Irvine. Without the restrictions of existing therapies, Hyaleon® is a 100% biological, mechanically strong cartilage implant that can repair both, big and minor articular cartilage lesions.

Which Region is Expected to Lead Market Going Forward?

“Rise in Funding for Stem Cell Therapy for Cartilage Regeneration in North America”

The market in North America is expected to rise at a significant CAGR during the forecast period as a result of increased government and private funding for stem cell therapy for cartilage regeneration and increased research into the use of scaffolds in the autologous chondrocyte implantation method.

The market in North America is primarily driven by rising orthopedic illness incidence, increased adoption of orthopedic surgery, athletic knee treatment, and rising numbers of bone and joint surgeries.

Country-wise Insights

What is the U.S.Knee Cartilage Repair Market Scenario?

“Rising Investments in R&D of Innovative Cartilage Repair Techniques in the U.S.”

The U.S. market is expanding due to an ageing population, an increase in joint problems including osteoarthritis, and a sharp rise in the number of obese people. The knee cartilage repair market is anticipated to be driven by an increase in arthroscopic chondroplasty treatments in the U.S.

The market in the U.S. is expanding as a result of the rising prevalence of musculoskeletal disorders, changing consumer lifestyles, rising adoption of advanced healthcare technology, growing investments in R&D of innovative cartilage repair techniques, and rising healthcare spending.

What is the Knee Cartilage Repair Market Outlook for China?

“Growing Awareness among Patients about Advanced Processes for Knee Cartilage Repair”

The China market is anticipated to rise at a CAGR of 7.7% from 2022 to 2027. Increasing investments by the government in knee cartilage repair treatments and growing concern among people regarding advanced technologies and processes for knee cartilage repair are expanding the knee regeneration industry size in China.

The market expansion in China was ascribed to the increased interest in sports among children and young people, the rising accident rate, and the growing focus on enhancing the healthcare system.

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Category-wise Insights

Which Treatment Modality Accounts for Highest Revenue Generation?

“Increasing Need for Minimally-Invasive Techniques to Restore Cartilage in Knees Driving Demand for Arthroscopic Chondroplasty”

Based on treatment modality, the knee cartilage repair market is segmented into, implants transplant, osteochondral grafts transplantation, cell-based cartilage resurfacing, arthroscopic chondroplasty, microfracture, autologous chondrocyte implantation.

Arthroscopic chondroplasty accounts for 60% share of the global market. A knee arthroscopy treatment called arthroscopic chondroplasty is used to rebuild knee cartilage that has suffered mild to severe damage. The damaged and loosening cartilage is removed during a minimally invasive outpatient operation using an arthroscope and small incision tools.

In an arthroscopic chondroplasty, the injured cartilage is examined through a tiny hole in the knee using a tiny surgical camera called an arthroscope, which enables the surgeons to see the operative site clearly without making significant cuts or incisions in the knee.

The injured cartilage is then removed with the aid of specialized equipment, and the surface is smoothed with the aid of surgical ablation tools. The damaged areas are subsequently replaced by growing healthy cartilage.

The convenience of arthroscopic chondroplasty as a minimally invasive technique along with technological advancements is also anticipated to boost demand throughout the projected period.

Why is the Popularity of Hyaline Cartilage Rising Rapidly?

“Hyaline Cartilage More Preferred to Support in Holding Joints Together”

The market is divided into two categories based on the type of cartilage: fibrocartilage, and hyaline cartilage. Hyaline cartilage accounts for the highest share in the global market.

Collagen, a protein found in connective tissues that helps hold the joints together, is widely distributed in hyaline. Numerous biological components benefit from the stability and flexibility that cartilage provides.

It gives shape and flexibility to other body parts, including the trachea, larynx, ears, nose, and other respiratory system organs. The articular surfaces of bones contain articular cartilage, commonly referred to as hyaline, which acts as a shock absorber and reduces friction in joints.

Which End User Will Account for High Revenue Generation?

“Superior Health Insurance Coverage for Hospital-based Medical Services Driving Cartilage Repair Market Share”

Based on end user, the market is classified into hospitals, specialty clinics, ambulatory surgery centers, and others. The high volume of knee cartilage repair procedures performed in hospitals.

Hospitals are the top end users for knee cartilage replacement procedures because these healthcare facilities are furnished with skilled and highly qualified medical staff as well as some of the most advanced equipment available today.

Well-equipped operating rooms, increased purchasing power, the accessibility of highly skilled medical personnel, and superior health insurance coverage for hospital-based medical services from numerous private and group insurance providers are the factors driving the knee regeneration demand in hospitals.

Competitive Landscape

Key companies in the cartilage repair and regeneration market are introducing new products and services. They are engaging in tactical actions including agreements, and partnerships to secure a commanding position in the market.

For instance :

  • Patients with a variety of changes in the knee and symptomatic full-thickness patella cartilage anomalies are now covered by Vericel Corporation's medical insurance coverage for MACI through UnitedHealthcare.

Key Segments in Knee Cartilage Repair Industry Research

  • By Treatment Modality :

    • Arthroscopic Chondroplasty
    • Autologous Chondrocyte Implantation
    • Osteochondral Grafts Transplantation
    • Cell-based Cartilage Resurfacing
    • Implants Transplant
    • Microfracture
  • By Cartilage Type :

    • Fibrocartilage
    • Hyaline Cartilage
  • By End User :

    • Hospitals
    • Specialty Clinics
    • Ambulatory Surgery Centers
    • Others
  • By Region :

    • North America
    • Europe
    • Asia Pacific
    • Latin America
    • Middle East & Africa

- FAQs -

What size will the global knee cartilage repair market reach?

The global knee cartilage repair market is set to reach US$ 5 billion by 2027.

At what CAGR is the knee cartilage repair market predicted to expand?

From 2022 to 2027, the market for knee cartilage repair is expected to evolve at a 5% CAGR.

Which are the top 3 countries in the knee cartilage repair market?

The U.S., China, and Canada are the top 3 countries in the market.

At what pace is the Latin American market expected to expand?

The market in Latin America is set to rise at 5.5% CAGR through 2027.

Which segment is leading in the knee cartilage repair market?

Arthroscopic chondroplasty leads the market with 60% share.

Which are the key companies in the knee cartilage repair market?

TiGenix NV, Vericel Corporation, and ISTO Biologics are players in this market.

Knee Cartilage Repair Market

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