Metagenomics Market

Metagenomics Market Outlook (2024 to 2034)

The global metagenomics market is analyzed to reach a value of US$ 217.7 million in 2024 and further increase at a CAGR of 6.3% to end up at US$ 428.6 million by the end of 2034.

Metagenomics is the new approach to studying microorganisms obtained from a specific environment by functional gene screening or sequencing analysis. Through this process, scientists can understand the functioning and toxicity of such organisms to make the general public aware of them. The market is projected to grow at a steady pace as government investments in research organizations grow.

In the bioprospecting of metagenomics data, primarily two types of analysis are employed: function-driven screening for an expressed trait and sequence-driven screening for a DNA sequence of interest. These methodologies follow distinct steps and varying degrees of precision, each suited to particular circumstances. These processes continue to evolve alongside advancements in scientific instrumentation, thereby enhancing result accuracy.

Key Market Growth Drivers

• Metagenomics has long been employed in astrobiology to help understand the origin, evolution, and distribution of life in extraterrestrial realms, including planets beyond Earth. Space agencies like NASA and ISRO harness this technique in the quest for Earth-like planets.
• In cancer research, this method has transformed the identification, analysis, and targeting of microbial diversity within tissue specimens from cancer patients, expediting the quest for cancer treatments.
• The agricultural domain has embraced metagenomics to discern and assess soil microbes, thereby enhancing agricultural productivity and soil health. An increasing number of farmers are adopting metagenomics to optimize vegetation growth.
• Industries such as food and beverages, often grappling with fermentation and fungal issues, use metagenomics to delve into microbial communities involved in food fermentation processes to improve food quality and safety standards. Major players in the food industry are making substantial investments to deliver high-quality products through metagenomics.
• Exploring microbes living in extreme environments like deep-sea habitats, hydrothermal vents, and polar regions aids in understanding the adaptations enabling various organisms to survive in harsh conditions. This broadens the comprehension of the metabolism and immune systems of different species.

Report Attribute	Detail
Metagenomics Market Size (2024E)	US$ 217.7 Million
Forecasted Market Value (2034F)	US$ 428.6 Million
Global Market Growth Rate (2024 to 2034)	6.3% CAGR
Canada Market Growth Rate (2024 to 2034)	7.3% CAGR
China Market Value (2034F)	US$ 44 Million
North America Market Share (2024E)	31.2%
East Asia Market Share (2034F)	21.6%
Latin America Market Value (2034F)	US$ 39 Million
Key Companies Profiled	Illumina Inc.; PerkinElmer Inc.; Thermo Fisher Scientific Inc.; Novogene Co. Ltd.; Promega Corporation; Takara Bio Inc.; Oxford Nanopore Technologies Plc; Eurofins Scientific; Zymo Research; Computomics GmbH; Microsynth AG; Arc Bio, LLC.

Which Aspects are Contributing to Metagenomics Market Size Expansion?

“Advancements in DNA Sequencing Technology and Personalized Medicine Initiatives”

Awareness of genetic disorders is on the rise, which is projected to drive the expansion of the market. The primary application of metagenomics is in clinical diagnostics. For instance, genetic disorders are becoming more prevalent in India. Due to the increase in genetic abnormalities and diseases, robust government support for genetic research and development, and advanced infrastructure, the North American region is projected to hold a significant share of the global market during the forecast period.

“Increased Investments in Microbiome Research”

Metagenomics is gaining popularity in microbiome research because it allows the analysis of all microorganisms, regardless of their ability to be cultured.
Metagenomics finds diverse applications in ecology, environmental studies, drug development, and clinical diagnosis, as well as the food and beverages industry.

Metagenomic investigations encompass pivotal stages: sampling, sequencing, processing sequence reads, assembly, gene prediction, binning, and functional annotation. Various sequencing methodologies, including 16S sequencing, whole-genome sequencing, and shotgun sequencing, are employed in metagenomics. A surge in investment in microbiome research is fueling the demand for metagenomics.

• In October 2023, Leucine Rich Bio, an Indian microbiome company, raised an undisclosed sum in a pre-series A round of financing. The organization aims to use the money to create and promote new products.

“Rising Prevalence of Bone and Joint Infections”

Clinical metagenomics is a relatively new approach for diagnosing infectious diseases. It makes use of next-generation sequencing (NGS) technology to identify etiologic agents, allowing for more effective and targeted treatment of infectious diseases.

Clinical metagenomics can be used to investigate central nervous system (CNS) infections. It can also be used to investigate bone and joint infections (BJIs). The high prevalence of BJIs is driving the metagenomics market growth.

• According to the National Institute of Health, each year, approximately 20,000 cases of septic arthritis are reported in the United States (7.8 cases per 100,000 person-year), with a comparable incidence in Europe. Septic arthritis is becoming more common among people over the age of 65, particularly those who are immunocompromised.

Which Restraints are Shrinking Opportunities for Market Players?

“Limited Availability of Data for Research and Lack of Necessary Instruments and Expertise”

One of the key limitations of metagenomics is the limited data available for the research. Scientists have to understand and gather information about microbes that they have never seen before and gathering information on the first test is quite impossible and this sometimes leads to wrong or less accurate results. Research organizations also often lack the instruments and knowledge to do tests on microorganisms in different environments, and this leads to further limited data and shrinks market opportunities to some extent.

Country-wise Evaluation

Market players across regions such as North America, East Asia, and Latin America are striving to stay competitive by keeping themselves updated on evolving market trends. The United States market is calculated to expand at a CAGR of 7.5% from 2024 to 2034, occupying a significant metagenomics market share of 76.8% in North America by 2034.

Why are Research Organizations Looking to Brazil for Future Prospects?

“Increasing Sophisticated Research & Medical Infrastructure and Funding for R&D Initiatives”

Attribute	Brazil
Market Value (2024E)	US$ 9 Million
Growth Rate (2024 to 2034)	13.5% CAGR
Projected Value (2034F)	US$ 17 Million

The Brazilian market is evaluated to grow at a remarkable pace during the forecast period. It is estimated to account for a significant portion of Latin America's market. This is due to the country's extensive research into genomics, oncology, and whole-genome sequencing. Other factors contributing to the widespread use of metagenomics technology in this country include sophisticated research and medical infrastructure, increased R&D funding, skilled personnel, and companies advocating for better research methods to identify newer technologies for diagnosis and therapy.

Which Conditions in China are Favoring Research Organizations?

“Extensive Infrastructure for Next-Generation Genome Sequencing Facilities”

Attribute	China
Market Value (2024E)	US$ 19 Million
Growth Rate (2024 to 2034)	8.5% CAGR
Projected Value (2034F)	US$ 44 Million

Because of the presence of prominent NGS centers such as BGI, China accounts for a sizable portion of the global market. Institutes have integrated NGS platforms and applications for prenatal screening, oncology, idiopathic, and infectious disease investigation and research.

• BGI has reportedly installed more than 120 Illumina HiSeq 2000 genome sequencers. Thus, the BGI NGS laboratory in Hong Kong is one of the few very high-capacity next-generation genome sequencing facilities.

Category-wise Insights

Based on end user, the pharmaceuticals segment accounts for a market share of 26% in 2024.

Which Product Type is Widely Used During Metagenomics Research?

“Straightforward Protocols and Reproducibility Associated with Library Preparation Kits”

Attribute	Library Preparation Kits
Segment Value (2024E)	US$ 91.9 Million
Growth Rate (2024 to 2034)	7.1% CAGR
Projected Value (2034F)	US$ 183.1 Million

Library preparation kits are essential for creating high-quality sequencing libraries. These kits provide several advantages, including simple protocols, reproducibility, and high yield. They also allow researchers to use a variety of starting materials.

Library preparation kits come in a variety of formats, including PCR-based and enzymatic methods, and can be customized for specific applications such as RNA-Seq, ChIP-Seq, and whole-genome sequencing. These kits are compatible with a wide range of sequencing platforms, making them an invaluable resource for genomics, transcriptomics, and epigenomics researchers. Overall, library preparation kits have revolutionized sequencing by simplifying the process and improving data quality.

How is Metagenomics Revolutionizing Clinical Diagnosis?

“Metagenomics Facilitating Enhanced Pathogen Detection and Early Disease Diagnosis”

Attribute	Clinical Diagnostics
Segment Value (2024E)	US$ 68.7 Million
Growth Rate (2024 to 2034)	7.6% CAGR
Projected Value (2034F)	US$ 142.4 Million

Metagenomics is being extensively used in clinical diagnosis to analyze all microorganisms present in a sample, irrespective of whether they can be cultured or not. This approach is useful in identifying pathogens that traditional methods cannot detect. Metagenomics can also identify genetic mutations responsible for inherited diseases, facilitating early diagnosis and treatment.

The technique provides a comprehensive view of a patient’s microbiome, which can aid the understanding of the interactions between microorganisms and their impact on human health. Metagenomics has the potential to provide faster, more accurate, and more comprehensive results.

Competitive Landscape

Key players in the metagenomics market are focusing on product approvals to extend their product reach and enhance availability across regions, as well as expansion to improve production/research activities. Market players are acquiring smaller companies to strengthen their market position. This enables businesses to enhance their capabilities, diversify their product portfolios, and also evolve themselves according to market trends such as metagenomics sequencing and genealogy products and services.

• PacBio signed an acquisition agreement with Apton Biosystems in August 2023. This acquisition is expected to hasten the development of Short-read Sequencers, accelerating the growth of sequencing.
• Illumina, Inc. launched its groundbreaking product, Illumina Complete Long Read technology, in March 2023. The technology enables both short and long reading in a single instrument.

Fact.MR provides detailed information about the price points of key organizations involved in metagenomics research positioned across the world, sales growth, production capacity, and speculative technological expansion, in this new market report.

Key Segments of Metagenomics Market Research

• By Product :

  • Library Preparation Kits
  • Sample Extraction Kits
  • Metagenomics Sequencing Kits

• By Application :

  • Microbial Diversity
  • Bioremediation & Degradation
  • Bio Surfactant & Antibiotic Production
  • Clinical Diagnosis

• By End User :

  • Pharmaceutical Industries
  • Research Laboratories
  • Biotechnology Companies
  • Pathology Laboratories
  • Academic & Research Institutes

• By Region :

  • North America
  • Latin America
  • Eastern Europe
  • Western Europe
  • East Asia
  • South Asia & Pacific
  • Middle East & Africa