Closed Blood Sampling Systems Market

Closed Blood Sampling Systems Market Size and Share Forecast Outlook 2025 to 2035

The global closed blood sampling systems market is projected to increase from USD 534.3 billion in 2025 to USD 870.3 billion by 2035, with a CAGR of 5.0% during the forecast period. The closed blood sampling systems market is growing due to rising hospital-acquired infection concerns, increasing demand for safe and efficient blood collection, and the shift toward advanced infection control practices, improving patient safety and reducing contamination risks in clinical and hospital settings.

Quick Stats of Closed Blood Sampling Systems Market

• Closed Blood Sampling Systems Market Size (2025): USD 534.3 billion
• Projected Closed Blood Sampling Systems Market Size (2035): USD 870.3 billion
• Forecast CAGR of Closed Blood Sampling Systems Market (2025 to 2035): 5.0%
• Leading Product Type Segment of Closed Blood Sampling Systems Market: Arterial
• Leading End-Use Segment of Closed Blood Sampling Systems Market: Hospitals
• Key Growth Regions of Closed Blood Sampling Systems Market: Germany. Brazil, Thailand
• Prominent Players in the Closed Blood Sampling Systems Market: Elcam Medical, CardioMed Supplies Inc., Shenzhen Antmed Co., Ltd., BD (Becton Dickinson), Sarstedt., and Others.

Metric	Value
Industry Size (2025E)	USD 534.3 billion
Industry Size (2035F)	USD 870.3 billion
CAGR (2025-2035)	5.0%

The global Closed Blood Sampling Systems market is forecast to expand from USD 534.3 billion in 2025 to USD 870.3 billion by 2035 at a CAGR of 5.0%. Growth is driven by an increasing number of surgical procedures and a growing demand for efficient blood management.

According to the World Health Organization, approximately 266.2 to 359.5 million surgeries were performed in 2012, a 38% increase over previous years, and the number is expected to rise further. This increase in surgical procedures and emergency cases, combined with a high demand for blood transfusions, is driving the use of closed blood sampling systems, which ensure safe, contamination-free collection and efficient sample handling.

Market revenue is expected to increase from USD 534.3 billion in 2025 to USD 561.0 billion in 2026, indicating early-stage expansion fueled by rising surgical volume. Patients admitted to intensive care units (ICUs) are driving the market growth. The National Center for Biotechnology Information (NCBI) reports that 30-37% of ICU patients receive blood transfusions, emphasizing the critical need for dependable closed blood sampling solutions.

The rising prevalence of trauma cases and chronic or life-threatening conditions such as cancer, HIV/AIDS, diabetes, coronary heart disease, rare diseases, and anemia is driving market growth, with revenue expected to reach USD 589.1 billion in 2027 and USD 618.5 billion in 2028 as adoption spreads throughout critical care and specialty units.

Epidemiological data highlight the increasing demand for blood testing and monitoring. For example, the Centers for Disease Control and Prevention (CDC) reported 26,203 cases of Lyme disease in the United States from 2006 to 2016. Furthermore, alcohol-impaired driving crashes killed approximately 10,265 people in 2015, accounting for 29% of all traffic-related fatalities, emphasizing the growing need for timely diagnostics in trauma and emergency care settings.

This trend indicates a projected market growth of USD 649.5 billion in 2029 and USD 681.9 billion in 2030, driven by emergency care and trauma-related testing. The market is expected to grow steadily, reaching USD 716.0 billion in 2031, USD 751.8 billion in 2032, USD 789.4 billion in 2033, USD 828.9 billion in 2034, and USD 870.3 billion in 2035. This growth is driven by rising surgical volumes, ICU patient needs, the prevalence of chronic and acute diseases, and the growing demand for safe, efficient blood collection in hospitals, emergency departments, and specialized clinics.

Key Closed Blood Sampling Systems Market Dynamics

Several key factors are driving the growth of the Closed Blood Sampling Systems Market, which is expanding rapidly. The rising prevalence of hospital-acquired infections (HAIs) has increased the demand for safer blood collection methods, while the growing adoption of advanced infection control practices is improving system integration in healthcare facilities.

Furthermore, increased demand for efficient and contamination-free blood sampling is driving market growth. However, certain constraints are limiting widespread adoption. Smaller healthcare providers face financial challenges due to the high initial setup and maintenance costs, while limited adoption in low-resource healthcare settings limits market penetration.

Moreover, the lack of skilled professionals to operate and maintain these systems effectively impedes their widespread implementation, despite their proven benefits in clinical settings.

Rising Prevalence of Hospital-Acquired Infections (HAIs)

Hospital-acquired infections are a significant global health concern, affecting millions of patients annually. Closed blood sampling systems minimise the risk of contamination during blood collection, thereby limiting the spread of pathogens within healthcare facilities. These systems improve patient and staff safety by preventing the spread of infectious materials.

Hospitals are increasingly using such systems as part of their infection prevention protocols. The growing emphasis on reducing HAIs has prompted investments in safer technologies to improve patient outcomes, lower treatment costs, and meet stringent infection control standards, resulting in increased demand for closed blood sampling systems worldwide.

Growing Adoption of Advanced Infection Control Practices

Healthcare institutions are prioritizing advanced infection control practices in order to improve care quality and reduce risks. Closed blood sampling systems support these practices by ensuring sterile specimen handling and minimising exposure to bloodborne pathogens. With regulatory bodies emphasizing strict hygiene standards, hospitals are transitioning to closed systems for increased safety and efficiency.

The systems enable streamlined workflows, fewer errors, and greater sample integrity. As healthcare providers invest in advanced infection prevention measures, the use of closed sampling solutions grows, emphasizing their importance in modernizing diagnostic procedures and improving overall patient safety.

Increasing Demand for Efficient and Contamination-Free Sampling

Efficient and contamination-free sampling has become critical in critical care and diagnostic environments. Closed blood sampling systems meet this demand by producing accurate, uncontaminated samples while minimizing waste and needle-stick injuries. Clinicians benefit from faster processing times and more consistent results, which are essential for timely diagnosis and treatment.

The technology also improves workflow efficiency by reducing the number of repeat tests required due to contaminated samples. As hospitals and diagnostic laboratories strive to improve processes and maintain high-quality standards, the preference for closed systems is growing. This trend promotes market expansion and establishes closed sampling as a superior alternative to traditional methods.

High Initial Setup and Maintenance Costs

The high costs of closed blood sampling systems can be prohibitive for smaller healthcare facilities and clinics. Significant financial resources are required for the purchase of specialized equipment, employee training, and ongoing maintenance. Budget-constrained providers may be hesitant to implement these systems, despite the long-term benefits they offer, such as decreased infections and increased efficiency.

Additionally, the cost of consumables associated with closed systems can raise operational costs. As a result, many smaller hospitals in developing countries postpone upgrading their blood collection processes, which limits widespread adoption and slows overall market growth despite the established benefits.

Limited Adoption in Low-Resource Healthcare Settings

Healthcare providers in low-resource settings frequently face financial and infrastructure barriers to the adoption of closed blood sampling systems. Traditional open systems are considered more cost-effective, despite posing greater contamination risks.

Limited understanding of the benefits of closed systems, combined with insufficient government funding, exacerbates the problem. In these areas, basic medical equipment often takes precedence over advanced sampling technologies.

The lack of infrastructure and logistical support for implementing closed systems continues to limit their use in emerging markets, limiting potential growth opportunities for manufacturers targeting these regions.

Lack of Skilled Professionals for Proper System Handling

Closed blood sampling systems can only be implemented successfully if skilled personnel are trained to operate and maintain them effectively. Many healthcare facilities, particularly in rural and underserved areas, suffer from a shortage of trained professionals. Improper handling or maintenance can lead to operational inefficiencies, system failures, and increased costs, ultimately discouraging future investment in these systems.

Hospitals may also experience workflow delays if employees are not properly trained, undermining the benefits of closed systems. Manufacturers and healthcare organizations must invest in training programs to address this skills gap, but adoption rates may remain low in the meantime.

Analyzing the Closed Blood Sampling Systems Market by Key Regions

North America dominates the market, accounting for a sizable portion of global revenue. The region's advanced healthcare infrastructure, rapid adoption of new technologies, and emphasis on patient safety all contribute to its market dominance. The North American market is expected to grow at a significant CAGR, driven by increased demand for safe and efficient blood sampling methods as well as the rising prevalence of chronic diseases.

Europe also has a significant market share, with countries such as Germany, France, and the United Kingdom leading the way in the adoption of closed blood sampling systems. The region's rising healthcare spending, combined with growing awareness of the benefits of these systems, is propelling market expansion. The European market is expected to grow steadily, driven by a focus on reducing hospital-acquired infections and improving patient outcomes.

The Asia-Pacific region is poised for significant expansion. The region's rapidly improving healthcare infrastructure, rising prevalence of chronic diseases, and rising healthcare spending are all key drivers of market growth. Closed blood sampling systems are being rapidly adopted in China, India, and Japan, driven by a growing demand for advanced medical technologies and a focus on patient safety.

Country-Wise Outlook

Country	CAGR (2025-2035)
Germany	5.7%
Brazil	7.7%
Thailand	6.5%

Germany's Growing Adoption of Advanced Closed Blood Sampling Systems

Germany's closed blood sampling systems market is expanding rapidly due to several factors. The country's robust healthcare infrastructure, which includes widespread access to advanced medical technologies, promotes the use of innovative solutions such as closed blood sampling systems.

Germany's healthcare system, which provides mandatory health insurance to 90% of the population, ensures that a large portion of the population has access to these cutting-edge medical technologies.

Technological advancements play a crucial role in driving market growth. Innovations in closed blood sampling systems have improved safety and efficiency, addressing the growing demand for infection control in healthcare settings. These advancements are especially relevant in intensive care units (ICUs), where frequent blood tests with low risk of contamination are critical.

Regulatory frameworks in Germany play a significant role in driving the market's growth. The German Medical Devices Act (Medizinproduktegesetz) and CE marking requirements ensure that closed blood sampling systems comply with stringent safety and quality standards. These regulations enhance confidence among healthcare providers and patients, promoting the adoption of these systems in various medical settings.

• Robust healthcare and insurance boost adoption
• Innovations improve ICU safety and efficiency
• Regulations ensure quality and trust

Brazil's Growing Focus on Safety and Infection Control in Closed Blood Sampling Systems

Brazil's closed blood sampling system market is growing as hospitals and diagnostic labs prioritize staff safety and infection control. Increased awareness of needlestick injuries and bloodborne pathogen exposure, particularly in urban teaching hospitals, drives the purchase of closed-tube and vacuum-based collection devices that reduce contamination risk and improve sample integrity.

Large private hospital groups and diagnostic chains in São Paulo, Rio de Janeiro, and Brasília are early adopters, implementing closed systems across phlebotomy units to standardise quality and streamline lab workflows. This institutional demand is supplemented by increasing adoption in specialized outpatient clinics and dialysis centers, where frequent blood draws necessitate safety and throughput.

Cost pressures continue to be a practical barrier in smaller hospitals and municipal clinics. Closed systems are more expensive per unit than conventional needles and tubes; therefore, adoption is frequently contingent upon procurement budgets or bundled-supply agreements that demonstrate total cost-of-care benefits through reduced infections and fewer repeat draws. Value-based contracting and bulk purchase frameworks are emerging as approaches to closing this gap.

• Urban hospitals and labs adopt closed systems to enhance safety and sample quality
• Private hospital chains and specialized clinics drive institutional demand
• Cost and budget constraints limit adoption in smaller facilities, addressed via bulk purchasing

Thailand's Rising Demand for Safe and Efficient Closed Blood Sampling Systems

Thailand's closed blood sampling system market is evolving as healthcare facilities enhance safety protocols and refine clinical workflows. The push for higher-quality patient care in Bangkok's advanced hospitals, combined with rising testing volumes across provincial networks, is increasing demand for systems that reduce contamination risks and improve efficiency.

The country's growing emphasis on universal health coverage has led to increased demand for diagnostic services, creating opportunities for suppliers of closed blood sampling systems. Hospitals in secondary cities are under pressure to adopt safer technologies in order to comply with biosafety and patient safety protocols. This shift is creating long-term demand across both public and private sectors.

The Thai Food and Drug Administration strictly regulates medical devices, ensuring that approved closed systems meet sterility, safety, and quality standards. This regulatory structure has attracted multinational suppliers while also encouraging local distributors to meet international standards. Such oversight increases healthcare providers' confidence in adopting advanced systems.

• Safety and efficiency drive demand
• Universal coverage expands adoption
• FDA regulations ensure quality

Category-wise Analysis

Arterial Segment is Leading in Accuracy, Safety, and Efficiency

The arterial segment is the most popular in the Closed Blood Sampling Systems Market, owing to its importance in obtaining accurate blood gas and biochemical measurements.

Arterial sampling is necessary for monitoring oxygenation, ventilation, and acid-base balance in critically ill patients, especially in intensive care units and operating rooms. Closed systems minimise the risk of contamination and unintentional exposure, thereby ensuring patient safety and consistent results.

Healthcare providers prefer arterial closed sampling systems because they reduce blood waste, streamline workflows, and improve diagnostic efficiency. Their precision and ability to support quick clinical decisions make them indispensable in treating severe conditions, such as respiratory failure and sepsis. This reliability and safety reinforce arterial sampling's market dominance.

• Arterial closed systems ensure accurate blood gas monitoring and patient safety
• Minimize blood waste and streamline critical care workflows
• Support rapid, precise clinical decisions in severe conditions like respiratory failure and sepsis

Hospitals Driving Growth are Ensuring Safe and Efficient Blood Sampling in Critical Care

The hospitals segment leads the Closed Blood Sampling Systems market, driven by the high demand for safe, accurate, and efficient blood sampling in critical care settings.

Hospitals, particularly intensive care units (ICUs) and surgical wards, rely on closed blood sampling systems to monitor patients’ oxygenation, ventilation, and biochemical parameters in real time. These systems help reduce blood wastage and minimize contamination risks, ensuring patient safety while supporting timely clinical decisions.

Healthcare facilities increasingly adopt closed blood sampling systems to comply with strict infection control protocols and prevent occupational exposure to bloodborne pathogens.

The integration of these systems into hospital workflows enhances operational efficiency, reduces turnaround times for diagnostic testing, and ensures reliable, reproducible results. This combination of safety, precision, and workflow optimization positions hospitals as the primary end-users driving market growth.

• Hospitals lead demand with safe, accurate sampling
• Systems enhance efficiency and reduce contamination
• Critical care protocols drive adoption

Competitive Analysis

The competitive landscape of the closed blood sampling systems market is characterized by a mix of established and emerging players, all vying for a piece of this growing market. Leading market players are focusing on research and development to innovate and improve their product offerings, catering to the changing needs of healthcare providers.

The introduction of new and improved products is expected to increase market competition, leading to further advancements and the adoption of closed blood sampling systems across various healthcare settings. Companies are also investing in strategic partnerships and collaborations to expand their market share and enhance their product portfolios.

Elcam Medical, CardioMed Supplies Inc., Shenzhen Antmed Co., Ltd., BD (Becton Dickinson), and Sarstedt are among the leading players in the closed blood sampling system market. To maintain their competitive advantage and capture a larger market share, these companies focus on product innovation and strategic partnerships.

Becton, Dickinson, and Company, for example, is well-known for its wide range of closed blood sampling systems, designed to enhance patient safety and diagnostic accuracy. The company's strong focus on research and development, as well as its commitment to innovation, have helped it establish itself as a market leader.

Key Players in the Market

• ICU Medical Inc.
• Smiths Medical Inc.
• Edwards Lifesciences Corporation
• Merit Medical Systems
• Utah Medical Products Inc.
• Elcam Medical
• CardioMed Supplies Inc.
• Shenzhen Antmed Co. Ltd.
• BD (Becton Dickinson)
• Sarstedt
• Greiner Bio-One
• Terumo Corporation
• Nipro Corporation

Recent Developments

• In December 2024, BD and Babson Diagnostics have expanded their fingertip blood collection technology throughout the United States' healthcare settings. By combining BD's MiniDraw system with Babson's BetterWay platform, they were able to obtain accurate lab-quality results from only six drops of capillary blood, bolstering BD's leadership in minimally invasive, patient-centered diagnostics.
• In June 2024, Streck introduced the Protein Plus BCT, a direct-draw whole blood collection tube intended to keep samples intact during storage, shipping, and handling. The tube contains a preservative reagent that reduces ex vivo hemolysis and platelet activation, minimizes interference from proteins released by blood cells, and aids in the maintenance of draw-time plasma protein concentrations during ambient temperature storage. This product launch improved the company's overall product portfolio.

Segmentation of Closed Blood Sampling Systems Market

• By Product Type :

  • Arterial
  • Venous
  • Others

• By End-Use :

  • Hospitals
  • Clinics
  • Others

• By Region :

  • North America
  • Latin America
  • Western Europe
  • Eastern Europe
  • East Asia
  • South Asia & Pacific
  • Middle East & Africa