Oligonucleotide Synthesis Market Forecast, Trend, Analysis & Competition Tracking - Global Market Insights 2020 to 2025

Published on : Jun-2020 | List of Tables : 96 | List of Figures : 100 | No. of Pages : 170 | Report Code : FACT4853MR | Format :

Path-breaking Developments in Synthetic Chemistry to Bolster Growth of Global Oligonucleotide Synthesis Market

Oligonucleotides are primarily used in biological and forensic applications in research, disease diagnosis, and therapeutics. Natural oligonucleotides have been extensively used for selection and determination of the DNA sequences such as hybridization probes or affinity purification, gene construction and site-directed mutagenesis. In addition, they are used to inhibit gene expression in in-vitro studies for diagnostic purposes.

Increased usage of oligonucleotides has augmented the need for technological developments in synthetic chemistry. Several biotechnology and pharmaceutical companies are thus engaged in the development of newer and advanced methods. For instance, Integrated DNA Technologies has developed oligonucleotides up to 200 base length which is used with mass spectrometry for manufacturing mini-genes. On the back of these trends, the global oligonucleotides synthesis market is anticipated to expand at a CAGR of 11.3% during the forecast period (2020-2025).

Therapeutics Application Mainstays for Oligonucleotide Synthesis, Research Segment to Catch-Up

Oligonucleotide synthesis is anticipated to find maximum application in therapeutics, as oligonucleotide therapeutics are hailed as the third major drug-development platform, next to small molecules and biologics. Therapeutic oligonucleotides such as antisense oligonucleotides and nucleic acid aptamers are the two major types of therapies available in the market. These are suitable for treating muscle dystrophy, cancer and other neurological disorders. Usage of oligonucleotide synthesis in therapeutics is expected to grow at a stellar CAGR of 18.4% during the forecast period.

Following therapeutics, research emerges as a key application area, attributing to the potential of using oligonucleotide synthesis in polymerase chain reactions (PCR) and next generation sequencing. Moreover, rising demand for drug development and discovery is anticipated to provide impetus to the market growth. Application of oligonucleotide synthesis in research is anticipated to register a CAGR of 10.0% through 2025.

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North America Leads the First Wave of Growth, Asia Pacific Promises New Opportunities

Asia Pacific is poised to expand most rapidly amongst all the regional markets during the forecast period, owing to its emergence as the world’s most promising life science research hub. Increase in life science research & development in developing economies and rise in government initiatives, grants, funds, and dedicated research commercial zones have attracted domestic and foreign market players to invest in the Asia Pacific’s market. The regional market is anticipated to expand at a staggering CAGR of 12.5% during the forecast period.

North America continues to reign supreme in the oligonucleotide synthesis market and is expected to expand at a CAGR of 10.0% through 2025. A fast growing life science industry, greater focus on genetics and genomics in research and diagnostic applications, and increased demand for high-quality oligonucleotides are attributed as key growth drivers. Moreover, pharmaceutical companies concentrating on oligonucleotides as therapeutic agents such as antisense and RNAi therapeutics are increasing in the region.

global oligonucleotide synthesis market growth forecast by region

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Key Players Prioritize New Product Development for Competitive Edge

The global oligonucleotide market is fragmented, with the top three players accounting for less than two-fifths share of the market. Some important players are: Thermo Fisher Scientific Corporation, Integrated DNA Technologies, Inc., Sigma-Aldrich Corporation (a part of Merck KGaA), GE Healthcare, Kaneka Eurogentec S.A., TriLink Biotechnologies, LLC (Maravai Life Sciences), BioAutomation and ATDBio Ltd., to name a few.

Integrated DNA Technologies is one of the leading players in the global oligonucleotide synthesis market, which supplies custom oligonucleotides for academic and pharmaceutical research as well as pharmaceutical drug development. It has a strong focus on delivering excellent customer service. Its products include the Ultramer DNA Oligos and Primer Mix DNA Plate Oligos.

BioAutomation, another player, provides automation solutions to research institutes to enable them to conduct research and development studies in the biotechnology industry. Its products include the MerMade 48X oligonucleotide synthesizer, the MerMade 96E oligonucleotide synthesizer and the MerMade 192E/R/X oligonucleotide synthesizers.

COVID-19 Impact Analysis

As the coronavirus pandemic tightens its iron-grip across the world, demand for effective diagnosis and treatment has also risen in the past 3-4 months. Presently, the most prevalent method of diagnosis of COVID-19 is through the real time polymerase chain reaction (RT-PCR) testing. However, pharmaceutical companies and healthcare providers are in the process of discovering more efficient ways of detecting the SARS-CoV-2 and preventing its spread among the patients. In this respect, oligonucleotide cocktails are proving extremely useful. Vendors such as bioSynthesis are developing oligonucleotide-based testing kits since the onset of the COVID-19. Some of its ready-to-use cocktail mixes include the SARS-CoV-2 N1 Oligo Mix, the SARS-CoV-2 N2 Oligo Mix and the Human RNase P (RP) Oligo Mix respectively. Such breakthroughs are generating a level of optimism amongst healthcare providers and stimulating them to keep the anti-coronavirus battle raging. The result is further expected to lead to positive growth of the oligonucleotide synthesis market.

The Analyst’s Viewpoint

“Simplistic methods of oligonucleotide synthesis have paved the way for novel technologies, thereby generating lucrative research and development opportunities for important manufacturers and stakeholders. Rapid synthesis and distribution of oligonucleotides has become paramount in assuring successful drug discovery enterprises.”

Global Oligonucleotide Synthesis Market: Report Scope

The recent study on global oligonucleotide synthesis market by Fact.MR provides a detailed analysis for the forecast period 2020-2025. The report sheds light on the key growth dynamics responsible for shaping the future outlook. The report maps potential drivers, restraints and opportunities associated with the market’s proliferation. A detailed segmental analysis, based on product, application and end user, has been included in the report.

The abovementioned segments are further profiled across the North American, European, Asia-Pacific, Latin American and Middle East & African landscapes. Towards the end of the study, a detailed competitive landscape has been detailed. In this section, information concerning the key market players, their revenue and market shares, product portfolios and key agreements has been provided. Lastly, a SWOT analysis of individual market players has been included to provide a realistic growth projection for the aforementioned forecast period.

Global Oligonucleotide Synthesis Market - Scope of the Report

The recent study by Fact.MR on global oligonucleotide synthesis market offers a 5-year forecast for the period of 2020-2025. The study analyzes crucial trends that are currently determining the growth of the global oligonucleotide synthesis market. The study report explicates on vital dynamics such as the drivers, restraints and opportunities for key market players along with key stakeholders as well as emerging players associated with the production of oligonucleotides. The study also provides dynamics that are responsible for influencing the future status of the global oligonucleotide synthesis market over the forecast period.

A detailed assessment of the global oligonucleotide synthesis market value chain, business execution, and supply chain across the regional markets has been covered in the report. A list of prominent companies operating in the global oligonucleotide synthesismarket along with their product portfolio enhances the reliability of this comprehensive research study.

Global Oligonucleotide Synthesis Market: Report Summary

The study offers a comprehensive analysis on diverse features including production capacities, demand, product developments, revenue generation, and sales in the global oligonucleotide synthesis market.

A comprehensive estimate of the global oligonucleotide synthesis market has been provided through an optimistic as well as a conservative scenario, taking into account the adoption of oligonucleotide synthesis during the forecast period. Price point comparison by region with global average price is also considered in the study.

Global Oligonucleotide Synthesis Market: Segmentation

Fact.MR has studied the global oligonucleotide synthesis market with detailed segmentation on the basis of product, application, end user and region.

Product

Application

End User

Region

  • Reagents & Consumables

Research:

  • Polymerase Chain Reaction (PCR)
  • Next Generation Sequencing
  • Others
  • Biotechnology & Pharmaceutical Companies
  • North America
  • Equipment

Therapeutics:

  • Antisense Oligonucleotides
  • Nucleic Acid Aptamers
  • Research Institutes
  • Europe
  • Synthesized Oligonucleotides:
  • DNA Oligonucleotides
  • RNA Oligonucleotides
  • Others
  • Diagnostics
  • Diagnostic Laboratories
  • Asia Pacific

 

 

 

  • Latin America

 

 

 

  • Middle East & Africa (MEA)

“This taxonomy prepared is confidential and intended exclusively for the individual or entity with whom it is being shared. Reading, disseminating, distributing, or copying this to any party other than addressee(s) is unauthorized and prohibited.”

Global Oligonucleotide Synthesis Market: Size Evaluation

The global oligonucleotide synthesis market has been analyzed for each market segment, in terms of value (US$ Mn).

Market estimates at global and regional levels for oligonucleotide synthesisis are available in terms of ‘US$ Mn’ for value. A Y-o-Y growth contrast on prominent oligonucleotide synthesis market segments along with market attractiveness evaluation has been incorporated in the report.

Global Oligonucleotide Synthesis Market: Regional Market Assessment

Key sections have been elaborated in the global oligonucleotide synthesis market report, which have helped deliver projection on the regional markets. These chapters include the regional macros (political, economic, and business environment outlook) which are expected to have a momentous influence on the global oligonucleotide synthesis market growth during the forecast period.

Country-specific valuation on demand for oligonucleotide synthesis has been offered for each regional market, along with the market scope, estimate and forecast, price index, and impact analysis of dynamics of prominence in regions and countries. For all regional markets, Y-o-Y growth estimates have also been incorporated in the report.

Detailed breakup in terms of value for emerging countries has also been included in the report.

Global Oligonucleotide Synthesis Market: In-Depth Analysis on Competitive Landscape

The report sheds light on the leading companies operating in the global oligonucleotide synthesis market along with their detailed profiles. Essential and up-to-date data and information related to the market performers, who are principally engaged in the production of oligonucleotides, has been brought with the help of a detailed dashboard view. Market share analysis and comparison of prominent players provided in the report permit the report readers to take preemptive steps in advancing their businesses.

Company profiles have been detailed in the report, which includes essentials such as product portfolio and key strategies along with all-inclusive SWOT analysis on each player. Company presence is mapped and presented through the matrix for all the prominent players thus providing the readers with actionable insights, which helps in thoughtfully presenting market status, and predicting the competition level in the global oligonucleotide synthesis market. Prominent manufacturers with established market presence in the global oligonucleotide synthesis market are Thermo Fisher Scientific Corporation, Integrated DNA Technologies, Inc., Sigma-Aldrich Corporation (a part of Merck KGaA), GE Healthcare, Kaneka Eurogentec S.A., TriLink Biotechnologies, LLC (Maravai Life Sciences), BioAutomation, and ATDBio Ltd., to name a few.

1. Executive Summary

    1.1. Global Market Outlook 

    1.2. Summary of Statistics

    1.3. Key Market Characteristics & Attributes

    1.4. Fact.MR Analysis and Recommendations

2. Market Overview

    2.1. Market Coverage / Taxonomy 

    2.2. Market Definition / Scope / Limitations

3. Market Risks and Trends Assessment 

    3.1. Risk Assessment 

        3.1.1. COVID-19 Crisis and Impact on Oligonucleotide Synthesis Demand

        3.1.2. COVID-19 Crisis and Impact on Oligonucleotide Synthesis Cost 

        3.1.3. COVID-19 Impact Benchmark with Previous Crisis 

            3.1.3.1. Change in Oligonucleotide Synthesis Demand 

            3.1.3.2. Before and After COVID-19 Crisis (Projected)

            3.1.3.3. Before and After Sub-prime Crisis – 2008 (Actual)

            3.1.3.4. Change in Demand post Recovery Period (After Each Crisis)

        3.1.4. Impact on Market Value (US$ Mn)

            3.1.4.1. Likely Loss of Value in 2020

            3.1.4.2. Mid-term and Long Term Forecast

            3.1.4.3. Quarter by Quarter Demand and Recovery Assessment 

        3.1.5. Anticipated Demand and Value Recovery Curve

            3.1.5.1. Likelihood of U-Shape Recovery

            3.1.5.2. Likelihood of L-Shape Recovery

        3.1.6. Recovery Period Assessment by Key Countries

        3.1.7. Recovery Assessment by Key Market Segments

        3.1.8. Action Points and Recommendation 

    3.2. Key Trends Impacting the Market

4. Market Background and Foundation Data Points 

    4.1. Global Healthcare Market Overview

    4.2. Healthcare Spending Analysis, By Key Countries

    4.3. Recent Developments in Oligonucleotide Synthesis Industry

    4.4. Growth and Development Patterns in Oligonucleotide Synthesis Market

    4.5. Market White Space Assessment And Opportunity Analysis

    4.6. Recent Development in Oligonucleotide Synthesis Market, By Market Players

    4.7. Competitive Scenario and Trends

        4.7.1. Oligonucleotide Synthesis Market Concentration Rate

        4.7.2. List of Emerging, Prominent and Leading Players 

        4.7.3. Mergers & Acquisitions

    4.8. Scenario Forecast (Demand in optimistic, likely, and conservative market conditions) 

    4.9. Policy and Regulatory Landscape

    4.10. Macro-Economic Factors

    4.11. Forecast Factors - Relevance & Impact

    4.12. Market Dynamics

        4.12.1. Market Driving Factors and Impact Assessment

        4.12.2. Prominent Market Challenges and Impact Assessment

        4.12.3. Oligonucleotide Synthesis Market Opportunities

        4.12.4. Prominent Trends in the Global Market & Their Impact Assessment

5. Key Success Factors 

    5.1. Oligonucleotide Synthesis Adoption / Usage Analysis

    5.2. Product USPs / Features

    5.3. Others (Discussed in Report)

6. Global Oligonucleotide Synthesis Market Value Analysis 2015-2019 and Forecast, 2020-2025

    6.1. Historical Market Value (US$ Mn) Analysis, 2015-2019

    6.2. Current and Future Market Value (US$ Mn) Projections, 2020-2025

        6.2.1. Y-o-Y Growth Trend Analysis

        6.2.2. Absolute $ Opportunity Analysis

7. Global Oligonucleotide Synthesis Market Analysis 2015-2019 and Forecast 2020-2025, By Product 

    7.1. Introduction / Key Findings

    7.2. Historical Market Size (US$ Mn) Analysis By Product, 2015-2019

    7.3. Current and Future Market Size (US$ Mn) Analysis and Forecast By Product, 2020 - 2025

        7.3.1. Reagents & Consumables

        7.3.2. Equipment 

        7.3.3. Synthesized oligonucleotides

            7.3.3.1. DNA oligonucleotides 

            7.3.3.2. RNA oligonucleotides

            7.3.3.3. Others

    7.4. Market Attractiveness Analysis By Product 

8. Global Oligonucleotide Synthesis Market Analysis 2015-2019 and Forecast 2020-2025, By Application

    8.1. Introduction / Key Findings

    8.2. Historical Market Size (US$ Mn) Analysis By Application, 2015-2019

    8.3. Current and Future Market Size (US$ Mn) Analysis and Forecast By Application, 2020 - 2025

        8.3.1. Research 

            8.3.1.1. Polymerase Chain Reaction 

            8.3.1.2. Next Generation Sequencing 

            8.3.1.3. Others

        8.3.2. Therapeutics 

            8.3.2.1. Antisense Oligonucleotides

            8.3.2.2. Nucleic Acid Aptamers

        8.3.3. Diagnostics 

    8.4. Market Attractiveness Analysis By Application

9. Global Oligonucleotide Synthesis Market Analysis 2015-2019 and Forecast 2020-2025, By End User

    9.1. Introduction / Key Findings

    9.2. Historical Market Size (US$ Mn) Analysis By End User, 2015-2019

    9.3. Current and Future Market Size (US$ Mn) Analysis and Forecast By End User, 2020 - 2025

        9.3.1. Biotechnology & Pharmaceutical Companies 

        9.3.2. Research Institutes  

        9.3.3. Diagnostic Laboratories

    9.4. Market Attractiveness Analysis By End User

10. Global Oligonucleotide Synthesis Market Analysis 2015-2019 and Forecast 2020-2025, by Region

    10.1. Introduction

    10.2. Historical Market Size (US$ Mn) Analysis By Region, 2015-2019

    10.3. Current Market Size (US$ Mn) Analysis and Forecast By Region, 2020 - 2025

        10.3.1. North America

        10.3.2. Latin America

        10.3.3. Europe

        10.3.4. Asia Pacific 

        10.3.5. Middle East and Africa (MEA)

    10.4. Market Attractiveness Analysis By Region

11. North America Oligonucleotide Synthesis Market Analysis 2015-2019 and Forecast 2020-2025

    11.1. Introduction

    11.2. Pricing Analysis

    11.3. Historical Market Size (US$ Mn) Trend Analysis By Market Taxonomy, 2015-2019

    11.4. Market Size (US$ Mn) Forecast By Market Taxonomy, 2020 - 2025

        11.4.1. By Country

            11.4.1.1. U.S.

            11.4.1.2. Canada

        11.4.2. By Product

        11.4.3. By Application

        11.4.4. By End User

    11.5. Market Attractiveness Analysis

        11.5.1. By Country

        11.5.2. By Product

        11.5.3. By Application

        11.5.4. By End User

12. Latin America Oligonucleotide Synthesis Market Analysis 2015-2019 and Forecast 2020-2025

    12.1. Introduction

    12.2. Pricing Analysis

    12.3. Historical Market Size (US$ Mn) Trend Analysis By Market Taxonomy, 2015-2019

    12.4. Market Size (US$ Mn) Forecast By Market Taxonomy, 2020 - 2025

        12.4.1. By Country

            12.4.1.1. Brazil

            12.4.1.2. Mexico

            12.4.1.3. Rest of Latin America

        12.4.2. By Product

        12.4.3. By Application

        12.4.4. By End User

    12.5. Market Attractiveness Analysis

        12.5.1. By Country

        12.5.2. By Product

        12.5.3. By Application

        12.5.4. By End User

13. Europe Oligonucleotide Synthesis Market Analysis 2015-2019 and Forecast 2020-2025

    13.1. Introduction

    13.2. Pricing Analysis

    13.3. Historical Market Size (US$ Mn) Trend Analysis By Market Taxonomy, 2015-2019

    13.4. Market Size (US$ Mn) Forecast By Market Taxonomy, 2020 - 2025

        13.4.1. By Country

            13.4.1.1. Germany

            13.4.1.2. France

            13.4.1.3. Italy

            13.4.1.4. Spain

            13.4.1.5. U.K.

            13.4.1.6. Russia

            13.4.1.7. Rest of Europe

        13.4.2. By Product

        13.4.3. By Application

        13.4.4. By End User

    13.5. Market Attractiveness Analysis

        13.5.1. By Country

        13.5.2. By Product

        13.5.3. By Application

        13.5.4. By End User

14. Asia Pacific Oligonucleotide Synthesis Market Analysis 2015-2019 and Forecast 2020-2025

    14.1. Introduction

    14.2. Pricing Analysis

    14.3. Historical Market Size (US$ Mn) Trend Analysis By Market Taxonomy, 2015-2019

    14.4. Market Size (US$ Mn) Forecast By Market Taxonomy, 2020 - 2025

        14.4.1. By Country

            14.4.1.1. China

            14.4.1.2. Japan

            14.4.1.3. India

            14.4.1.4. Australia & New Zealand

            14.4.1.5. Rest of Asia Pacific

        14.4.2. By Product

        14.4.3. By Application

        14.4.4. By End User

    14.5. Market Attractiveness Analysis

        14.5.1. By Country

        14.5.2. By Product

        14.5.3. By Application

        14.5.4. By End User

15. Middle East and Africa Oligonucleotide Synthesis Market Analysis 2015-2019 and Forecast 2020-2025

    15.1. Introduction

    15.2. Pricing Analysis

    15.3. Historical Market Size (US$ Mn) Trend Analysis By Market Taxonomy, 2015-2019

    15.4. Market Size (US$ Mn) Forecast By Market Taxonomy, 2020 - 2025

        15.4.1. By Country

            15.4.1.1. GCC Countries

            15.4.1.2. South Africa

            15.4.1.3. Rest of Middle East and Africa

        15.4.2. By Product

        15.4.3. By Application

        15.4.4. By End User

    15.5. Market Attractiveness Analysis

        15.5.1. By Country

        15.5.2. By Product

        15.5.3. By Application

        15.5.4. By End User

16. Market Structure Analysis

    16.1. Market Analysis by Tier of Companies 

    16.2. Market Concentration

    16.3. Market Share Analysis of Top Players

    16.4. Market Presence Analysis

        16.4.1. By Regional footprint of Players

        16.4.2. Product footprint by Players

        16.4.3. Channel footprint by Players

17. Competition Analysis

    17.1. Competition Dashboard

    17.2. Competition Benchmarking

    17.3. Competition Deep Dive 

        17.3.1. GE Healthcare

            17.3.1.1. Overview

            17.3.1.2. Product Portfolio

            17.3.1.3. Sales Footprint

            17.3.1.4. Strategy Overview

        17.3.2. Thermo Fisher Scientific 

            17.3.2.1. Overview

            17.3.2.2. Product Portfolio

            17.3.2.3. Sales Footprint

            17.3.2.4. Strategy Overview

        17.3.3. Agilent Technologies, Inc

            17.3.3.1. Overview

            17.3.3.2. Product Portfolio

            17.3.3.3. Sales Footprint

            17.3.3.4. Strategy Overview

        17.3.4. Merck KGaA 

            17.3.4.1. Overview

            17.3.4.2. Product Portfolio

            17.3.4.3. Sales Footprint

            17.3.4.4. Strategy Overview

        17.3.5. Integrated DNA Technologies, Inc

            17.3.5.1. Overview

            17.3.5.2. Product Portfolio

            17.3.5.3. Sales Footprint

            17.3.5.4. Strategy Overview

        17.3.6. Kaneka Eurogentec S.A. (Kaneka Corporation) 

            17.3.6.1. Overview

            17.3.6.2. Product Portfolio

            17.3.6.3. Sales Footprint

            17.3.6.4. Strategy Overview

        17.3.7. TriLink BioTechnologies,LLC  (Maravai Life Sciences) 

            17.3.7.1. Overview

            17.3.7.2. Product Portfolio

            17.3.7.3. Sales Footprint

            17.3.7.4. Strategy Overview

        17.3.8. BioAutomation

            17.3.8.1. Overview

            17.3.8.2. Product Portfolio

            17.3.8.3. Sales Footprint

            17.3.8.4. Strategy Overview

        17.3.9. ATDBio Ltd

            17.3.9.1. Overview

            17.3.9.2. Product Portfolio

            17.3.9.3. Sales Footprint

            17.3.9.4. Strategy Overview

        17.3.10. Gene Design, Inc

            17.3.10.1. Overview

            17.3.10.2. Product Portfolio

            17.3.10.3. Sales Footprint

            17.3.10.4. Strategy Overview

        17.3.11. Eurofins Genomics

            17.3.11.1. Overview

            17.3.11.2. Product Portfolio

            17.3.11.3. Sales Footprint

            17.3.11.4. Strategy Overview

        17.3.12. Other Prominent Players 

18. Assumptions and Acronyms Used

19. Research Methodology

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Oligonucleotide Synthesis Market Forecast, Trend, Analysis & Competition Tracking - Global Market Insights 2020 to 2025