Mixed Mode Chromatography Resin Market

Global Mixed Mode Chromatography Resin Market Outlook

The mixed mode chromatography resin market is predicted to grow at an impressive CAGR of 15.7% during the forecast period covering 2022 to 2032. The mixed mode chromatography resin market share is estimated to reach a value of nearly US$ 428 Million by 2032 growing from US$ 91 Million recorded in 2021.

Attributes	Details
Mixed Mode Chromatography Resin Market Share (2021)	US$ 91 Million
Mixed Mode Chromatography Resin Market Size Value (2022)	US$ 99.6 Million
Mixed Mode Chromatography Resin Market Size Value (2032)	US$ 428 Million
Mixed Mode Chromatography Resin Market Growth Rate (2022-2032)	15.7%
Mixed Mode Chromatography Resin Market Key Players	Bio-Rad Laboratories, Inc. GE Healthcare Purolite Corporation Danaher Corporation Avantor JSR Micro Inc. Kaneka Corporation Thermo Fisher Scientific Sepragen Corporation Merck among others.

An interface base or mixed-mode media employed in the chromatographic process is defined as mixed mode chromatography resin that uses ligands with multimodal functionality to enable protein adsorption through a mix of ionic, hydrogen, and hydrophobic interactions.

The need for separating the solution from the constituent of both organic compounds and inorganic compounds is what makes the demand for mixed mode chromatography resin higher in several end-use industries.

Global Mixed Mode Chromatography Resin Market Historical Analysis (2015-2021) Vs. Forecast Outlook (2022-2032)

As per the mixed mode chromatography resin market demand analysis conducted by the Fact.MR, the year-on-year growth rate of the average global market has leaped through several points in comparison to the previous analysis period. As stated by the mixed mode chromatography resin market report, the CAGR for the global market was registered to be around 9.5% during the time period covering 2015 to 2021.

Numerous sectors of the economy incurred losses as a result of the COVID-19 Pandemic as a result of imposed lockdowns and supply chain disruptions. Contrastingly, the global mixed mode chromatography resin market has witnessed a rise in demand as a result of the pandemic emergencies.

As antibody manufacturing is one of the key applications of this substance, so there was a surge in demand across the regions, as reported by the global market study on mixed mode chromatography resin consumption levels.

Pharmaceutical firms responded swiftly to this opportunity of developing medications to battle and ease the symptoms of COVID-19 and other disorders in general mass, which boosted the demand for mixed mode chromatography resin in those days.

What is the Future of Global Mixed Mode Chromatography Resin Market?

“Extensive use of mixed mode chromatography resin in chemical, pharmaceutical, environmental research, and biochemistry laboratories and several other industries have strengthened its market in all major economies of the world.”

Until now, the chromatography process has been used in chemical, pharmaceutical, environmental science, and biochemistry laboratories as a suitable process for cleaning, separating, and testing mixtures included in sophisticated blends.

These sectors of the economy have been the forerunners in determining the mixed mode chromatography resin market key trends and opportunities. However, the advancements in science and technology it has introduced this method to several other industrial processes, further boosting the sales of mixed mode chromatography resin in the global market.

What are the Favourable Opportunities for the Global Mixed Mode Chromatography Resin Market Outlook?

 For the purification of monoclonal antibodies, used in cancer and other therapeutic treatments like Alzheimer's disease and autoimmune and inflammatory illnesses, the deployment of chromatography as a crucial step has skyrocketed in the last couple of years. Because of the increased number of patients, there has been an increase in demand for therapeutic treatments promising ample mixed mode chromatography resin market opportunities in the coming days.

Also, as a result of this development, practically all of the major pharmaceutical corporations have invested in therapeutic antibody research and development. Anionic contaminants, viz nucleic acids and endotoxins, are removed from monoclonal antibodies using anion exchange chromatography, which is further likely to boost the mixed mode chromatography resin market growth.

On the other hand, biosimilars are one of the fastest-growing biologics market in the world. During the forecasted period, a number of firms operating in this sector are expected to be encouraged to engage in the development of biosimilars due to the expiration of previous patents in this field. Escalation in the use of chromatography for bio-separation techniques utilized in the production of a biosimilar is expected to enhance the mixed mode chromatographic resin market future trends as well.

Other significant reasons driving the expansion of the mixed mode chromatographic resin business include the exhilarated availability of government and corporate financing for biotechnology and pharmaceutical research. The rise of the pharmaceutical sector in several non-traditional areas, and the implementation of tight regulatory rules for drug development and release have mandated higher sales of mixed mode chromatographic resin in the emerging economies.

What are the Several Constraints Experienced for the Mixed Mode Chromatography Resin Market Growth?

With the cost of crude material rising, it has resulted in an increase in the overall cost of chromatography process that is anticipated to be a restraining factor for the mixed mode chromatography resin market future trends. . In the upcoming years, the increasing cost of mixed mode chromatography resin compared to alternative bases for separation processes is expected to pose as a major challenge for the mixed mode chromatography resin market players.

Several local and global market for mixed mode chromatography resin is being challenged by rising raw material costs owing to the ongoing trade war among larger economies. During the forecast period of 2022 to 2032, however, the requirement for highly skilled workers to implement these chromatography procedures is predicted to be a major limitation for the mixed mode chromatography resin market growth.

Regional Outlook

What is the Performance of Mixed Mode Chromatography Resin Market in Different Geographical Regions?

In accordance with this new market research report on mixed mode chromatography resin, North America is expected to continue to lead the global market, powered primarily by the United States (US). With the aid of higher government investments in new research activities, the U.S. mixed mode chromatography resin market has reached a total valuation of US$ 36.2 Million by 2022.

This new market research report on mixed mode chromatography resin also sheds light on the performance of the overall pharmaceutical industry in North America, which grew by 3.3 percent in the year 2020, having a major influence on the target market.

With respect to such developments, the US mixed mode chromatography resin market is projected to grow at a rate of 15.5% and reach a total valuation of US$ 152.4 Million by the end of this forecast period in 2032.

Although the Europe pharmaceutical industry grew by 3.9 percent, as reported by the European Federation of Pharmaceutical Industries and Associations EFPIA, this substantial growth was found to be not encouraging for the mixed mode chromatography resin market to that proportion in that region. Interestingly, while other markets were in decline for the pharmaceutical industry and its extension, the mixed mode chromatography resin survey reported a surge in demand during the previous decade.

What is the Mixed Mode Chromatography Resin Market Outlook for the Asia Pacific Region?

As evident from the global mixed mode chromatography resin market statistics, in the future years, Asia Pacific is expected to be the fastest-growing regional market, with many local players scaling up their contribution with each passing year.

China is the leading market in this geographical part, with a current valuation of US$ 7.6 Million for the year 2022. The China mixed mode chromatography resin market is also figured out to be the second-fastest-growing market, with an overall CAGR of 15% over the forecast period of 2022 to 2032.

Japan and South Korea are also the two leading economies contributing significantly to the emerging trends in mixed mode chromatography resin market of the Asia Pacific region, standing at a net valuation of US$ 6.7 Million and US$ 4.4 Million, respectively. Higher healthcare infrastructure, increased disposable income in developing nations, and easy access to a modest but talented workforce are all expected to promote the biotechnology industry in the growing Asia Pacific economy, hence fuelling the mixed mode chromatography resin market growth.

Furthermore, the economic boom in the Asia Pacific is expected to accelerate all establishments, including mixed mode chromatography resin industry, significantly. Such progress in the regional mixed mode chromatography resin market might be ascribed to the Indian and Chinese governments' efforts to promote their pharmaceutical and biotechnology industries.

Segmentation Outlook

What is the Growth Outlook for the Mixed Mode Chromatography Resin Market According to Different Segments?

“One of the key drivers for the mixed mode chromatography resin market is the increase in the number of manufacturing and research companies in the several backward economies.”

In the wake of the robust expansion in drug discovery efforts in both developed and developing countries, the ion exchange - hydrophobic resin has emerged as the prominent segment of the global mixed-mode chromatography resin market on the basis of the technique. In terms of revenue and volume, this particular segment is also predicted to grow at the highest CAGR of 15.5% during the forecast period of 2022 to 2032.

The hydroxyapatite type segment is also poised to gain some higher demand by mixed mode chromatography resin manufacturers during the forecast period owing to some recent discoveries in its uses in the pharmaceutical and other industries.

What are the Major Applications of the Mixed Mode Chromatography Resin by Different Market Segments?

By the year 2021-22, antibody production has the highest share in the application category of the mixed mode chromatography resin market accounting for up to 50% of the total. This has grown increasingly important in recent years since demand for COVID-19 vaccinations has increased dramatically and has rendered the growth rate of antibodies production segment at an astounding 15.2% for the upcoming forecast period.

As stated in FDA rules, the usage of chromatography in the pharmaceutical end-use industry is also increasing, which is positively affecting the mixed mode chromatography resin market trends. The European Medical Agency has also formulated a strategy to assure medication safety to its citizens that is expected to stimulate the regional mixed mode chromatography resin market adoption trends in the pharmaceutical segment.

How Strong is the Competitive Landscape for the Mixed Mode Chromatography Resin Market?

Some of the prominent mixed mode chromatography resin market players are Bio-Rad Laboratories, Inc., GE Healthcare, Purolite Corporation, Danaher Corporation, Avantor, JSR Micro Inc., Kaneka Corporation, Thermo Fisher Scientific, Sepragen Corporation, and Merck among others.

Recent Developments in the Global Mixed Mode Chromatography Resin Market

• Kaneka Corporation released a new version of "KANEKA KanCapA 3G," that is a novel protein resin chromatography for immune response therapy, in January 2017. KanCapA 3G from KANEKA has a 50 percent greater binding rate than a regular product and is designed to lower antibody treatment process expenses and increase productivity. As a consequence, the KANEKA KanCapA 3G is projected to improve processing time, reduce pollution, and increase operational efficiencies.
• Celsee, Inc. is a firm that provides tools and consumables for the separation, identification, and characterization of single cells, which was acquired by Bio-Rad Laboratories, Inc. in April 2020. Celsee's cutting-edge products and technology are intended to broaden Bio-reach Rad's into the fast-growing fields of precision medicine and single-cell analysis, which both provide better understanding of illness, diagnosis, and therapy.

Key Segments

• By Type :

  • Ion Exchange Hydrophobic Type
  • Hydroxyapatite Type
  • Others

• By Application :

  • Antibodies Production
  • Vaccine Production
  • Non-antibody Proteins
  • Antibody-drug Conjugate
  • Separation of Low Molecular Weight Impurities
  • Others

• By Region :

  • North America
  • Latin America
  • Europe
  • Asia Pacific
  • Middle East and Africa (MEA)