High Performance Liquid Chromatography (HPLC) Market

High Performance Liquid Chromatography (HPLC) Market Study by Instruments, Consumables, and Accessories for Diagnostic Laboratories, Food & Beverage Industry, and Others from 2023 to 2033

Analysis of High Performance Liquid Chromatography (HPLC) Market Covering 30+ Countries Including Analysis of US, Canada, UK, Germany, France, Nordics, GCC countries, Japan, Korea and many more

High Performance Liquid Chromatography (HPLC) Market Outlook (2023 to 2033)

Expanding at a CAGR of 6%, the global high performance liquid chromatography (HPLC) market is projected to increase from a valuation of US$ 5 billion in 2023 to US$ 9 billion by the end of 2033. Government initiatives to develop small-scale industries, as well as the entry of existing key players in emerging countries, is anticipated to influence the growth of pharmaceutical & biotechnology industries.

The chromatographic method used to separate various substances from a mixture is known as high-performance liquid chromatography. The method makes use of a column filled with a solid adsorbent material, a glass reservoir to hold the solution, multiple pumps to move the pressurized liquid solvent containing the sample mixture, fluorescence, mass spectrometric, ultraviolet-spectroscopic, and electrochemical detectors, as well as data collection systems.

Individual component identification, quantification, and purification are widely done in analytical chemistry and biochemistry. As a result, the technique has several uses in the creation of pharmaceutical drugs, clinical disease diagnosis, trace analysis, and quality control of food products.

High-performance liquid chromatography is a method used for analyzing and separating proteins, amino acids, vitamins, and additives in the food industry. Additionally, it can be utilized to identify and isolate contaminants from food. Future market growth is anticipated to be fueled by increasing government initiatives to reduce environmental impact and food safety, as well as a growing emphasis on precise diagnostics and acceptance of chromatographic techniques as a standard method for confirming the validity and specificity of medication components.

High performance liquid chromatography techniques have forayed into forensic sciences, wherein they are used to identify the presence of therapeutic drugs in body fluids or tissue samples. They are used for drug analysis, separation of molecules, and environmental control in the pharmaceutical industry.

High performance liquid chromatography is used in the pharmaceutical sector at all stages of drug research and development. During the production process, it is used to qualitatively and quantitatively assess the components of medications.

Increasing interest in liquid chromatography-mass spectrometry, rapid adoption of high performance liquid chromatography in pharmaceutical manufacturing for quality control testing, faster results, and separation are the elements driving market value. The growing usage of pharmaceuticals in both developed and developing countries is another factor boosting the global demand for high performance liquid chromatography.

The high frequency of acute and chronic illnesses, as well as the rising demand for preclinical and clinical studies in the drug development process, are propelling market revenue growth. High speed, selective analysis, and the use of the sample as preparation are further major factors propelling market growth.

Report Attributes


High Performance Liquid Chromatography Market Size (2023)

US$ 5 Billion

Projected Market Value (2033)

US$ 9 Billion

Global Market Growth Rate (2023 to 2033)


Market Share of Consumables


Key Companies Profiled

  • Shimadzu Corporation
  • PerkinElmer, Inc.
  • Gilson, Inc.
  • Tosoh Corporation
  • Waters Corporation
  • Bio-Rad Laboratories, Inc.
  • Thermo Fisher Scientific Inc.
  • Agilent Technologies, Inc.
  • GE HealthCare Technologies Inc.

What Key Aspects are Influencing the High Performance Liquid Chromatography Market?

“Rapid Innovations in High Performance Liquid Chromatography Techniques”

The market is predicted to expand due to new developments in high performance liquid chromatography techniques that have improved the dependability and robustness of liquid chromatography processes. The effectiveness of high performance liquid chromatography in disease monitoring and drug identification is fueling market growth.

Recent advancements have made it easier to conduct high-quality analysis that produces more precise results faster and increases user convenience in general. The significant factor driving market expansion is the creation of novel column designs by high performance liquid chromatography equipment manufacturers that can withstand high pressure from minute, superficially porous particles.

Furthermore, high performance liquid chromatography is preferred over other chromatography methods such as gas chromatography because of its dependability and precision. Key players in the industry are creating unique, high-pressure-capable columns and advancing technology to enhance the result. This is probably going to fuel market expansion during the forecast period.

“Significant Research & Development Efforts in Life Sciences”

The global high performance liquid chromatography market is primarily driven by escalating investments in the healthcare sector. Many private and governmental entities are making significant investments in healthcare R&D. This will introduce high performance liquid chromatography products with advanced new technology and increase the possibilities of the healthcare sector. Additional aspects that are anticipated to drive the market further include the expanding biobanking trend and significant research and development efforts in life sciences.

One of the main elements fostering market growth is the rapid expansion of the pharmaceutical industry. The analysis of medication samples, quality assurance, the production of complicated pharmaceuticals, and the generation of quicker and more precise compound separation results are all common uses of high performance liquid chromatography.

The market is expanding as a result of rising demand for high performance liquid chromatography systems for the purification of monoclonal antibodies. Other growth-promoting elements include various developments in column and pump technology, as well as the creation of smaller, automated, and computerized high performance liquid chromatography equipment.

Pharmaceutical companies are subject to stringent regulations put forth by governmental bodies. As a result, they are using high performance liquid chromatography more extensively to ensure that items are of exceptional quality before they are released for sale. To meet the growing demand from end users in the healthcare industry, such as pharmaceutical and biotechnology industries, several businesses are investing in high performance liquid chromatography products.

Don't Need a Global Report?

save 40%! on Country & Region specific reports

How is Industry Growth Being Restrained to Some Extent?

Lack of Skilled Professionals and High Cost of HPLC Systems”

The high cost of high performance liquid chromatography systems is restraining market growth, as per pricing trends. Market expansion is hampered by a lack of skilled professionals and the customer and supplier's respective negotiating positions. Government restrictions are yet another significant factor that limits the market.

High Performance Liquid Chromatography (hplc) Growth Forecast by Fact.MR

How are New Companies Penetrating this Industry?

“New Market Players Introducing Innovative HPLC Systems”

New entrants are employing tactics, including creating user-friendly and innovative high performance liquid chromatography systems, mergers and acquisitions, strong research and development, and geographical expansion to maintain a substantial position in the global market.

  • A start-up based in the U.S., Axcend®, offers advanced and small capillary high performance liquid chromatography systems that significantly enhance portability, use, quick and easy deployment, and connectivity to other analytical systems.

More Insights, Lesser Cost (-50% off)

Insights on import/export production,
pricing analysis, and more – Only @ Fact.MR

Why is Europe Dominating the Global Market for High Performance Liquid Chromatography?

“Increase in Pharmaceutical Firms Driving Market Growth in Europe”

Europe is an attractive high performance liquid chromatography market with 50% share attributed to a growing emphasis on drug discovery and an increase in pharmaceutical firms. A rise in the geriatric population with chronic illnesses who need effective drug treatment regimens and a supportive regulatory environment for high performance liquid chromatography are supporting market expansion in Europe.

Country-wise Insights

What is the Market Outlook for HPLC in the United States?

“Presence of Highly Advanced Government-funded Research Centers

Strict regulatory standards by the United States Food and Drug Administration for ensuring the quality of food and drugs, the existence of highly advanced government-funded research centers pioneering drug discovery and development, and the presence of major market players are the key factors fueling market growth. Major drivers influencing market revenue growth include an increase in preclinical activities by pharmaceutical companies and the advanced healthcare system.

Why is Germany a Prominent Market for High Performance Liquid Chromatography?

“Growing Demand for Clinical Diagnostic Applications”

Market expansion in Germany is accelerated by the rapidly expanding pharmaceutical industry, growing demand for clinical diagnostic applications, a high level of scientific awareness, and the accessibility of experts with the necessary skills. The prominent presence of diagnostic laboratories is also contributing to market growth.

How is Japan Aiding Market Growth in Asia Pacific?

“Increase in Research Activities to Introduce Novel Drug Formulations”

The market in Japan is expected to rise at a CAGR of 4% over the forecast period. Market growth in Japan is attributed to an increase in research activities to introduce novel drug formulations, a rise in the local supply of HPLC products, growing public awareness of health issues, a huge patient pool, and the widespread production of generic drugs.

Know thy Competitors

Competitive landscape highlights only certain players
Complete list available upon request

Category-wise Insights

Why is the Demand for Consumables So High?

“Consumables Widely Used for Shielding HPLC Components from Particle Contamination

Based on product, the market is divided into instruments, consumables, and accessories. Consumables account for 50% share of the global market.

Consumables are anticipated to gain popularity as a result of advancements in packing materials and column chemistries, as well as the growing significance of filtering procedures for shielding high performance liquid chromatography columns from any particle contamination. An emphasis has been placed on reducing analyte-metal interactions that can affect the findings due to the rising demand for chromatography operations with high sensitivity.

Consumables have a positive sales outlook as a result of advancements in chiral compound separation technology and the production of columns with uniform porosity than current column packing, which improves the separation of biomolecules. The life of high performance liquid chromatography components is ultimately extended by the employment of in-line filters and guard columns, which shield the particles from system wear and chemical contamination.

Which End User is Dominating in Terms of Revenue Generation?

“Increasing Need for Novel Therapeutics Driving Demand for HPLC Technologies in Pharmaceutical & Biotechnology Industries

Based on end user, the market is classified into pharmaceutical & biotechnology industries, diagnostic laboratories, food & beverage industry, academic & research institutes, and others. Pharmaceutical & biotechnology industries hold 40% share of the global market.

Pharmaceutical and biopharmaceutical companies are anticipated to expand significantly over the coming years as a result of the increased global need for novel therapeutics to combat the epidemic of chronic diseases. Pharmaceutical & biotechnology industries use high performance liquid chromatography technologies for a variety of purposes, such as quality control, determining the purity of drugs, characterizing drug candidates, assessing the stability of pharmaceutically active components, and more.

The food & beverage industry is anticipated to find the maximum application of high performance liquid chromatography principles. Increasing consumer demand for nutritious food with better packaging is anticipated to propel the growth of the food and beverage industry across the forecast period.

Competitive Landscape

Key companies are heavily investing in strengthening their product portfolio by following safety regulations and enhancing quality control. Top high performance liquid chromatography system providers are focusing on improving product standards and supply chain management to gain a competitive edge in the market.

Major high performance liquid chromatography component manufacturers are always working to improve the components' value, such as by making technical changes to the sample injection port, chemical changes to the extraction columns, and sample detector improvements.

For instance,

  • Waters Corporation is a leading life sciences company that designs, develops, and markets liquid chromatography instruments, such as the Alliance HPLC System, which provides advanced solvent delivery capabilities.
  • Agilent Technologies, Inc. specializes in three categories of HPLC systems, including analytical, application-specific, and preparative systems.
  • In 2020, a revolutionary analytical tool called the Vanquish core HPLC Systems was unveiled by Thermo Fisher Scientific Inc. This equipment helps to enhance laboratory practices by automatically detecting, monitoring, and calculating solvent and waste levels.

High Performance Liquid Chromatography Industry Research Segmentation

  • By Product :

    • Instruments
    • Consumables
      • Columns
      • Filters
      • Vials
      • Tubes
    • Accessories
  • By End User :

    • Pharmaceutical & Biotechnology Industries
    • Diagnostic Laboratories
    • Food & Beverage Industry
    • Academic & Research Institutes
    • Others
  • By Region :

    • North America
    • Europe
    • Asia Pacific
    • Latin America
    • Middle East & Africa

- FAQs -

What is the estimated growth rate of the high performance liquid chromatography market?

The use of high performance liquid chromatography systems is anticipated to increase at a CAGR of 6% through 2033.

What is the future size of the market for high performance liquid chromatography?

The global high performance liquid chromatography market is estimated to reach US$ 9 billion by 2033.

Which product accounts for a leading market share?

Consumables hold 50% share of the global HPLC market.

Why is the adoption of high performance liquid chromatography systems surging globally?

High prevalence of acute and chronic disorders is driving market revenue growth.

What is the current high performance liquid chromatography market size?

Global high performance liquid chromatography system demand is valued at US$ 5 billion in 2023.

High Performance Liquid Chromatography (HPLC) Market

Schedule a Call