Bioactive Materials Market

Bioactive Materials Market Growth Outlook

The global revenue from bioactive materials in 2020 was US$ 2 Billion. The industry is likely to expand at a projected CAGR of 11.3% during 2021 – 2031.

Bioactive composite materials are expected to be the highest revenue generating segment, accounting for an absolute dollar opportunity of nearly US$ 1.7 Billion over the next ten years. 

Consumption Analysis of Bioactive Materials from 2016 to 2020 Compared to Demand Outlook for 2021 to 2031

As per the bioactive materials industry research by Fact.MR - a market research and competitive intelligence provider, historically, from 2016 to 2020, market value of the bioactive materials industry increased at around 9.9% CAGR, where revenue was largely dominated by countries such as the U.S., Germany, U.K., China, and Japan.

In the recent past, age-related pathologies have mushroomed along with the aging population. This has created significant increase in demand for bioactive materials to repair age-borne damaged tissues.

Bioactive scaffolds display high efficiency in tissue repair, and their high mechanical efficiency, biocompatibility, and load-bearing capabilities makes them suitable for regenerative medicine applications. Besides these characteristics, they are also promising for soft tissue engineering.

With these dynamics, demand for bioactive materials is projected to increase at a CAGR of 11.3% over the coming 10 years.

• The bioactive materials market reached a valuation of US$ 2 Billion in 2020, while demand witnessed low, though positive growth amid the COVID-19 pandemic.
• Fact.MR estimates that bioactive materials revenue will grow 2.9X from 2021 to 2031, reaching nearly US$ 6.2 Billion in 2031.
• Revenue from bioactive composite materials will account for over 40% share, owing to their suitability for skin tissue engineering and cardiovascular tissue repair.
• Revenue from moldable bioactive materials is expected to grow 190 BPS during the forecast period.
• Bioactive material demand in bioengineering applications is projected to grow 3X by 2031.
• Top 5 providers of bioactive materials held around 23% market share in 2020.

Bioactive Material: Prospective Candidate for In-situ Drug Delivery Models – What is the Reality?

Bioactive materials have been studied for a considerable time for in-situ drug delivery. Through the usage of bioactive materials, alongside favouring tissue regrowth, peri-implant traumas can also be avoided.

Recent researches on nano-science impart strong indication about the applicability of bioceramics in drug delivery of antibiotic, anti-osteoporotic, and anticancer compounds, owing to their carrier suitability.

Considering these implications, bioactive material sales are expected to cross the US$ 6 Bn mark by 2031.

From Medical Applications to Food Preservation, How are Bioactive Materials Suited for New Applications?

Owing to their characteristics, biomaterials have started to find use across new applications. Quebec, in Canada, produces significant volumes of strawberries, though considering the vulnerability of the fruit, they need proper packaging.

In 2021, Monique Lacroix, a professor at the Institut national de la recherche scientifique, along with her team, developed a bioactive packaging film that keeps strawberries fresh for nearly 12 days. This packaging also hasantimicrobial properties, which makes it further suited for this application.

In another instance, the BioActive Materials project conducted by researchers at Fraunhofer-Gesellschaft, led to the development of an eco-friendly coating for paper packaging. When put into application, not only is plastic saved, but the coating of plant-based proteins and waxes also extends the shelf life of the food.

While it will be too early to comment on the commercial scale viability of bioactive materials for food, it is indicative of their open prospects in newer applications.    

Which Region Accounts for the Largest Demand for Bioactive Materials?

With an absolute dollar opportunity of US$ 1.2 Bn, North America would remain the most lucrative region for bioactive material manufacturers. The key reason for the highest market share is it highly developed healthcare sector.

The dentistry industry in both, the U.S. and Canada is advanced, and uses advanced technologies. The North American dental consumables market stood at US$ 7 Bn in in 2020. Besides, population to dentist ratio in the region has also been on the rise. Dentistry, being one of the core application areas of bioactive materials, is expected to offer significant opportunities over the coming years. 

Country-wise Analysis

Which Country is Projected to Offer the Largest Opportunity for Bioactive Material Manufacturers?

There has been significant rise in oral cancer cases in China in the recent past, which has led to demand explosion of advanced dentistry and oral care products, including bioactive materials.

According to BMC Oral Health, between 1990 and 2017, total number of oral cancer cases in China increased 280% and 79.7% for new cases and age-based incidence, respectively. This took the number of deaths and age-based mortality at 196.8% and 29%, respectively, in the country.

According to The Cancer Registry Report, published by the National Central Cancer Registry of China, in 2015, there were about 4.3 Mn new cancer cases and 2.8 Mn cancer deaths in China. Out of this, nearly 48,100 new cases and 22,100 deaths were caused due to oral and oropharyngeal cancer, which accounted for 1.1% and 0.8% of all new cancer cases and deaths, respectively.

Owing to these alarming numbers, the country has been gearing up for advanced technologies in dentistry, and consequently, demand growth for bioactive materials of over 13% can be expected in China over the next ten years.              

Category-wise Insights

Which Bioactive Material Accounts for the Largest Revenue Share?

Bioactive composite materials accounted for over 40% revenue of the market in 2020. The capability of bioactive composite materials to regenerate dental hard tissues makes them a preferred choice.        

Why are Powdered Bioactive Materials Preferred for Biomedical Applications?

Powdered bioactive materials accounted for over 40% bioactive material revenue in 2020.

Biomedical applications, including tissues, scaffolds, and fixation devices need specific fabrication. Thus, the process, without rigid support structures is recommended, which involves the use of imprinted powders that support complex parts during the printing process.  

How Has COVID-19 Impacted Revenue Generation from Bioactive Materials?

Revenue from bioactive materials witnessed slow growth with the onset of the COVID-19 pandemic, though growth remained positive.

As compared to nearly 12% year-on year market growth in 2019, demand grew by around 5% in 2020. Since, most of the applications of bioactive materials fall under the healthcare category, their manufacturing was less impacted with lesser restrictions being imposed on this sector.

Competitive Landscape

According to market research analysis, partnerships and product developments featured among the key developments in the global bioactive materials market.

Recent developments by key bioactive material providers are as follows:

• In July 2021, Arthrex announced distribution agreement with Celularity under which the former will receive rights for distribution and commercialization of Celularity’s biomaterial products for orthopaedics and sports medicine that are placental-derived.
• In June 2021, Lineage Cell Therapeutics, Inc. announced it granted an option to Amasa Therapeutics, Inc., a biopharmaceutical company, to acquire a royalty-bearing license to utilize HyStem technology of Lineage Cell Therapeutics for the development and marketing of therapies for treatment of solid tumors under pre-negotiated terms.

Similarly, recent developments related to companies offering bioactive materials have been tracked by the team at Fact.MR, which are available in the full report.

Bioactive Materials Market Report Scope

Report Attributes	Details
Forecast Period	2021-2031
Historical Data Available for	2016-2020
Key Regions Covered	North America Latin America Europe East Asia South Asia Oceania MEA
Key Market Segments Covered	Material Type Application Region
Key Companies Profiled	Zimmer Holding Inc. Medtronic Inc. Stryker Corporation DePuy Synthes Biomatlante Arthrex, Inc. Pulpdent Corporation Bioactive Bone Substitutes Oy Lasak s.r.o Bioretec Ltd. Noraker Septodont Holding C.I. TAKIRON Corporation Lineage Cell Therapeutics

Market Segments Covered in Bioactive Materials Industry Analysis

• By Material

  • Bioactive Glass
  • Bioactive Glass Ceramic
  • Bioactive Composite Material
  • Other Bioactive Materials

• By Type

  • Powdered
  • Moldable
  • Granulated
  • Injectable

• By Application

  • Dentistry
  • Surgery
  • Bioengineering
  • Other Applications