Global CRISPR and Cas Genes Market Size and Growth Outlook
The global CRISPR and Cas genes market shows stellar future growth prospects, expanding at a CAGR of 21.2% during the forecast period (2020-2026). Advancements in the field of genome editing have facilitated increased adoption of CRISPR-Cas systems in diagnostics and in the assessment of evolutionary analysis in prokaryotes. The technique is specifically used to understand the evolution of bacteria. Governments worldwide have encouraged investments in genome editing advancements, paving the way for the CRISPR and Cas genes market growth.
The most important development in this field is the introduction of the Cas-9 technique. This is a revolutionary step in the field of biomedical research. The application of CRISPR/Cas 9 focuses on somatic cell genome editing and aims to accelerate treatment for various genetic disorders. Moreover, it is projected that the COVID-19 pandemic shall find credible applications of this technique to understand the mutation of the novel coronavirus. Studies have proven that CRISPR-based tests provide more accurate test results compared to other techniques such as RT-PCR tests.
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Global CRISPR and Cas Genes Market: Technological Insights
Genome editing is broadening the ability to elucidate the contribution of genetics to diagnostics by facilitating more accurate cellular and animal models of pathological processes. Genome editing techniques such as Zinc Finger Nucleases (ZFNs), Transcription Activator-like Effector Nucleases (TALENs), mega nucleases and Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) are being investigated as promising approaches to human gene therapy. The CRISPR technology is being increasingly used for researching on genetic diseases.
The discovery and characterization of CRISPR and Cas genes have fueled the recent development of a flexible, democratized genome-engineering toolbox based on programmable targeting of CRISPR and Cas systems. The technology is being widely used in research to find treatment options for neurodegenerative diseases. For instance, the technique is being applied to investigate possible treatment approaches for Huntington’s disease. The use of Cas9 nuclease provides safe and efficient means of targeting the Huntington gene by deletion of abnormal repetition along with inhibiting toxic protein synthesis.
Global CRISPR and Cas Genes Market: Product Insights
Vector-based-Cas systems dominated the global CRISPR and Cas genes market during the historical period, capturing over 3/5th of the market value share. This trend is poised to continue over the forecast period, capturing a similar market share and expanding at a CAGR of 20.9%. However, DNA-free-Cas systems are anticipated to catch up, growing at a CAGR of 21.7% through 2026 and accounting for 2/5th of the global CRISPR and Cas genes market value.
Production of high level expression of protein and RNA over several days, reduction in potential off-targets, and the possibility of finding correlations with human diseases in model systems will continue to push the demand for vector-based Cas systems. Growth in demand for DNA-free systems is attributed to rising awareness about multiple CRISPR-Cas applications across various fields such as drug discovery, biomedical research, non-transgenic bleeding and clinical therapies.
Global CRISPR and Cas Genes Market: Application Insights
Genome engineering is anticipated to find maximum application of CRISPR-Cas based techniques over the forecast period, capturing more than half of the total market share. The disease models segment is catching up, expanding 3.3x and capturing nearly one-fifth of the market value.
Enabling of programmable genetic, epigenetic and transcriptomic engineering is anticipated to push the scope of application in genome engineering. Widespread usage in research projects is also poised to influence market prospects for genome engineering. Application of CRISPR-Cas systems in disease models is anticipated to surge on the back of immunology-focused applications such as the targeting of C-C chemokine receptor type 5 and programmed death-1 gene.
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Global CRISPR and Cas Genes Market: Regional Insights:
North America is poised to be at the vanguard of the global CRISPR and Cas genes market over the forecast period. The region will capture almost half of the total market value, expanding at a CAGR of 21.6%. However, Asia-Pacific is set to expand the fastest at a CAGR of 23.2% through 2026 and capture more than 1/5th of the market share.
Increased funding for research activities to provide modified products for preventing chronic diseases is anticipated to drive the North America’s CRISPR and Cas genes market growth. A clinical trial was initiated in 2016 in the United States to use CRISPR for disease treatment. The need for genetically engineered treatment options for chronic diseases such as cancer is anticipated to improve growth prospects of the market in Asia Pacific.
Global CRISPR and Cas Genes Market: Competition Structure
The global CRISPR and Cas genes market is highly fragmented, comprising of numerous small players. It is estimated that 50% of the total market share is collectively held by companies which individually do not account for more than 8% of the global market. Prominent market players in the industry are Addgene, Integrated DNA Technologies (IDT) and Thermo Fisher Scientific. A strong distribution network across the globe, wide product portfolio of CRISPR plasmids, and collaboration with research institutes are major factors augmenting the revenue share of these companies.
Thermo Fisher Scientific has a broad range of CRISPR-Cas products such as the CRISPR-Cas9 101, CRISPR Protein, CRISPR gRNA, Cas9 Lentivirus and CRISPR Plasmids among others. The company also partnered with Synthego to distribute synthetic Guide RNA products for CRISPR in 2017. Likewise, Addgene offers products such as SapTrap CRISPR, CRISPi-Kit Gasser and CRISPaint Kit- Hornung.
COVID-19’s Impact on the Market
The outbreak of the COVID-19 pandemic has generated shockwaves across the world, with infection rates rising on a daily basis. Presently, over 3 million active cases have been reported, out of which more than two hundred thousand people have succumbed to the disease. Despite the massive number, healthcare providers have unnervingly cared for the sick, trying to minimize the casualty rates.
The global CRISPR and Cas genes market is anticipated to burgeon amid the pandemic. Until now, hospitals have been relying on the RT-PCR based testing systems to diagnose COVID-19 patients. However, fluctuations in the reading of swabs often provide unreliable results. Therefore, healthcare organizations are exploring the possibilities of CRISPR-Cas9 based testing which are proven to guarantee a nearly 100% accuracy rate. With the pandemic in full swing, the adoption of CRISPR-based diagnostics is only expected to burgeon in the future. Moreover, the pandemic is anticipated to break through the commercialization barriers faced by the CRISPR-based diagnostics industry. Analysts are also hopeful that the diagnosis might eventually pave way for possible treatment and eradication of the virus altogether.
“The global CRISPR and Cas genes market is anticipated to ride on the back of rapid advancements in genomic testing. The ongoing coronavirus pandemic only serves to provide further impetus to the market, as researchers are hopeful of finding a way to inhibit the mutation of the virus. North America and Asia-Pacific promise to generate immense growth opportunities, owing to rising investments in advanced testing mechanisms.”
Global CRISPR-Cas Genes Market: Report Scope
The recent study by Fact.MR on the Global CRISPR and Cas genes market incorporates a six-year forecast period, 2020-2026. The report explicates on vital dynamics such as the key drivers, opportunities and restraints impacting the market in the future. The study has been conducted on the following segments: product, application, and end user. Each segment contains a detailed analysis based on market share, revenue and growth rate across the forecast period. The study also covers an exclusive chapter on the COVID-19 impact analysis to help stakeholders in better decision-making.
A detailed regional landscape across five geographies (North America, Europe, Asia-Pacific, Latin America and Middle East & Africa) has also been incorporated within the scope of this report. Each region includes an in-depth study of the segments enumerated above. In addition, a competition landscape has been provided towards the conclusion of the report. This section provides information on the prominent market players engaged in providing CRISPR-based products, their revenue shares, key collaborations and a SWOT analysis to predict a realistic outlook for each company’s future growth.
Global CRISPR and Cas Genes Market- Scope of the Report
The recent study by Fact.MR on the global CRISPR and cas genes market offers a 6-year forecast for the period 2020-2026. The study analyzes crucial trends that are currently determining the growth of the global CRISPR and cas genes market. This report explicates on vital dynamics such as the drivers, restraints and opportunities for key market players and emerging players associated with the production and supply of CRISPR and cas genes. The study also provides dynamics responsible for influencing the future status of the CRISPR and cas genes market over the forecast period.
A detailed assessment of the global CRISPR and cas genes market value chain analysis, business execution, and supply chain analysis across the regional markets has been covered in the report. A list of prominent companies operating in the global CRISPR and cas genes market along with their product portfolio enhances the reliability of this comprehensive research study.
Global CRISPR and Cas Genes Market: Report Summary
The study offers a comprehensive analysis on diverse features including production capacities, demand, product developments, revenue generation and sales in the CRISPR and cas genes market across the globe.
A comprehensive estimate of the market has been provided through an optimistic as well as a conservative scenario, taking into account the sales in the global CRISPR and cas genes market during the forecast period. Price point comparison by region with global average price is also considered in the study.
Global CRISPR and Cas Genes: Market Segmentation
Fact.MR has studied the global CRISPR and cas genes market with detailed segmentation on the basis of product, application, end user and region.
Biotechnology & Pharmaceutical Companies
Academic & Government Research Institutes
Contract Research Organizations
Middle East & Africa (MEA)
“This taxonomy prepared is confidential and intended exclusively for the individual or entity with whom it is being shared. Reading, disseminating, distributing, or copying this to any party other than addressee(s) is unauthorized and prohibited.”
Global CRISPR and Cas Genes Market: Market Size Evaluation
The global CRISPR and cas genes market has been analyzed for each market segment, in terms of value (US$ Mn).
Market estimates at global and regional levels for CRISPR and cas genes is available in terms of “US$ Mn” for value. A Y-o-Y growth contrast on prominent global CRISPR and cas genes market segments along with market attractiveness evaluation has been incorporated in the report.
Global CRISPR and Cas Genes Market: Inspected Assessment on Regional Segments
Key sections have been elaborated in the global CRISPR and cas genes report, which have helped deliver projection on the regional markets. These chapters include the regional macros (economic, and business environment outlook), which are expected to have a momentous influence on the growth of the global CRISPR and cas genes market during the forecast period.
Country-specific valuation on demand for global CRISPR and cas genes has been offered for each regional market along with the market scope estimate and forecast, price index, and impact analysis of dynamics of prominence in regions and countries. For all regional markets, Y-o-Y growth estimates have also been incorporated in the report.
Detailed breakup in terms of value for emerging countries has also been included in the report.
Global CRISPR and Cas Genes Market: In-Depth Analysis on Competitive Landscape
The report sheds light on the leading manufacturers of CRISPR and cas genes along with their detailed profiles. Essential and up-to-date data information related to market performers, who are principally engaged in the production of CRISPR and cas genes, has been brought with the help of a detailed dashboard view. Market share analysis and comparison of prominent players provided in the report permits the report readers to take preemptive steps in advancing their businesses.
Company profiles have been included in the report, which includes essentials such as product portfolio, key strategies along with all-inclusive SWOT analysis of each player. Company presence is mapped and presented through the matrix for all the prominent players thus providing the readers with actionable insights, which helps in thoughtfully presenting market status, and predicting the competition level in the global CRISPR and cas genes market. Prominent manufacturers with established market presence in the global CRISPR and cas genes market areAddgene, Thermo Fisher Scientific Inc., Integrated DNA Technologies, Inc. and Synthego among others.
1.1. Market Definition and Scope
1.2. Market Segmentation
1.3. Key Research Objectives
1.4. Research Highlights
2. Assumptions and Research Methodology
3. Executive Summary: Global CRISPR and Cas Genes Market
4. Market Overview
4.1.1. Product Definition
4.1.2. Industry Evolution / Developments
4.2.1. Global CRISPR and Cas Genes Market Size (US$ Mn) Forecast, 2020–2026
4.2.2. Global CRISPR and Cas Genes Market Outlook
4.2.3. Evolution of CRISPRs
4.2.4. Research institutes involved in CRISPR Research
4.2.5. CRISPR: Funding & Investment
4.2.6. Mergers and Acquisitions
4.3. Market Dynamics
5. Global CRISPR and Cas Genes Market Analysis and Forecasts, by Product
5.1. Introduction & Definition
5.2. Market Value Forecast, by Product, 2020–2026
5.2.1. Vector-based Cas
5.2.2. DNA-free Cas
5.3. Market Attractiveness, by Product
6. Global CRISPR and Cas Genes Market Analysis and Forecasts, by Application
6.1. Introduction & Definition
6.2. Market Value Forecast, by Application, 2020–2026
6.2.1. Genome Engineering
6.2.2. Disease Models
6.2.3. Functional Genomics
6.3. Market Attractiveness, by Application
7. Global CRISPR and Cas Genes Market Analysis and Forecasts, by End user
7.1. Introduction & Definition
7.2. Market Value Forecast, by End-user, 2020–2026
7.2.1. Biotechnology & Pharmaceutical Companies
7.2.2. Academic & Government Research Institutes
7.2.3. Contract Research Organizations
7.3. Market Attractiveness, by End-user
8. Global CRISPR and Cas Genes Market Analysis and Forecasts, by Region
8.1. Key Findings
8.2. Market Value Forecast, by Region
8.2.1. North America
8.2.3. Asia Pacific
8.2.4. Latin America
8.2.5. Middle East & Africa
8.3. Market Attractiveness, by Country/Region
9. North America CRISPR and Cas Genes Market Analysis and Forecast
9.2. Market Value Forecast, by Product, 2020–2026
9.2.1. Vector-based Cas
9.2.2. DNA-free Cas
9.3. Market Value Forecast, by Application, 2020–2026
9.3.1. Genome Engineering
9.3.2. Disease Models
9.3.3. Functional Genomics
9.4. Market Value Forecast, by End-user, 2020–2026
9.4.1. Biotechnology & Pharmaceutical Companies
9.4.2. Academic & Government Research Institutes
9.4.3. Contract Research Organizations
9.5. Market Value Forecast, by Country, 2020–2026
9.6. Market Attractiveness Analysis
9.6.1. By Product
9.6.2. By Application
9.6.3. By End-user
9.6.4. By Country
10. Europe CRISPR and Cas Genes Market Analysis and Forecast
10.2. Market Value Forecast, by Product, 2020–2026
10.2.1. Vector-based Cas
10.2.2. DNA-free Cas
10.3. Market Value Forecast, by Application, 2020–2026
10.3.1. Genome Engineering
10.3.2. Disease Models
10.3.3. Functional Genomics
10.4. Market Value Forecast, by End-user, 2020–2026
10.4.1. Biotechnology & Pharmaceutical Companies
10.4.2. Academic & Government Research Institutes
10.4.3. Contract Research Organizations
10.5. Market Value Forecast, by Country/Sub-region, 2020–2026
10.5.6. Rest of Europe
10.6. Market Attractiveness Analysis
10.6.1. By Product
10.6.2. By Application
10.6.3. By End-user
10.6.4. By Country/Sub-region
11. Asia Pacific CRISPR and Cas Genes Market Analysis and Forecast
11.2. Market Value Forecast, by Product, 2020–2026
11.2.1. Vector-based Cas
11.2.2. DNA-free Cas
11.3. Market Value Forecast, by Application, 2020–2026
11.3.1. Genome Engineering
11.3.2. Disease Models
11.3.3. Functional Genomics
11.4. Market Value Forecast, by End-user, 2020–2026
11.4.1. Biotechnology & Pharmaceutical Companies
11.4.2. Academic & Government Research Institutes
11.4.3. Contract Research Organizations
11.5. Market Value Forecast, by Country/Sub-region, 2020–2026
11.5.4. Rest of Asia Pacific
11.6. Market Attractiveness Analysis
11.6.1. By Product
11.6.2. By Application
11.6.3. By End-user
11.6.4. By Country/Sub-region
12. Latin America CRISPR and Cas Genes Market Analysis and Forecast
12.2. Market Value Forecast, by Product, 2020–2026
12.2.1. Vector-based Cas
12.2.2. DNA-free Cas
12.3. Market Value Forecast, by Application, 2020–2026
12.3.1. Genome Engineering
12.3.2. Disease Models
12.3.3. Functional Genomics
12.4. Market Value Forecast, by End-user, 2020–2026
12.4.1. Biotechnology & Pharmaceutical Companies
12.4.2. Academic & Government Research Institutes
12.4.3. Contract Research Organizations
12.5. Market Value Forecast, by Country/Sub-region, 2020–2026
12.5.3. Rest of Latin America
12.6. Market Attractiveness Analysis
12.6.1. By Product
12.6.2. By Application
12.6.3. By End-user
12.6.4. By Country/Sub-region
13. Middle East & Africa CRISPR and Cas Genes Market Analysis and Forecast
13.2. Market Value Forecast, by Product, 2020–2026
13.2.1. Vector-based Cas
13.2.2. DNA-free Cas
13.3. Market Value Forecast, by Application, 2020–2026
13.3.1. Genome Engineering
13.3.2. Disease Models
13.3.3. Functional Genomics
13.4. Market Value Forecast, by End-user, 2020–2026
13.4.1. Biotechnology & Pharmaceutical Companies
13.4.2. Academic & Government Research Institutes
13.4.3. Contract Research Organizations
13.5. Market Value Forecast, by Country/Sub-region, 2020–2026
13.5.1. GCC Countries
13.5.2. South Africa
13.5.3. Rest of Middle East & Africa
13.6. Market Attractiveness Analysis
13.6.1. By Product
13.6.2. By Application
13.6.3. By End-user
13.6.4. By Country/Sub-region
14. Competition Landscape
14.1. Market Player - Competition Matrix (By Tier and Size of companies)
14.2. Market Share Analysis, by Company (2018)
14.3. Company Profiles (Details - Overview, Financials, Recent Developments, Strategy)
188.8.131.52. Company Overview
184.108.40.206. Financial Overview
220.127.116.11. Product Portfolio
18.104.22.168. SWOT Analysis
22.214.171.124. Strategic Overview
14.3.2. Thermo Fisher Scientific, Inc.
126.96.36.199. Company Overview
188.8.131.52. Financial Overview
184.108.40.206. Product Portfolio
220.127.116.11. SWOT Analysis
18.104.22.168. Strategic Overview
22.214.171.124. Company Overview
126.96.36.199. Financial Overview
188.8.131.52. Product Portfolio
184.108.40.206. SWOT Analysis
220.127.116.11. Strategic Overview
18.104.22.168. Company Overview
22.214.171.124. Financial Overview
126.96.36.199. Product Portfolio
188.8.131.52. SWOT Analysis
184.108.40.206. Strategic Overview
14.3.5. Merck KGaA (Sigma-Aldrich)
220.127.116.11. Company Overview
18.104.22.168. Financial Overview
22.214.171.124. Product Portfolio
126.96.36.199. SWOT Analysis
188.8.131.52. Strategic Overview
14.3.6. Integrated DNA Technologies, Inc.
184.108.40.206. Company Overview
220.127.116.11. Financial Overview
18.104.22.168. Product Portfolio
22.214.171.124. SWOT Analysis
126.96.36.199. Strategic Overview
14.3.7. Transposagen Biopharmaceuticals, Inc.
188.8.131.52. Company Overview
184.108.40.206. Financial Overview
220.127.116.11. Product Portfolio
18.104.22.168. SWOT Analysis
22.214.171.124. Strategic Overview
14.3.8. OriGene Technologies, Inc.
126.96.36.199. Company Overview
188.8.131.52. Financial Overview
184.108.40.206. Product Portfolio
220.127.116.11. SWOT Analysis
18.104.22.168. Strategic Overview
14.3.9. New England Biolabs
22.214.171.124. Company Overview
126.96.36.199. Financial Overview
188.8.131.52. Product Portfolio
184.108.40.206. SWOT Analysis
220.127.116.11. Strategic Overview
14.3.10. Dharmacon, a Horizon Discovery Group Co.
18.104.22.168. Company Overview
22.214.171.124. Financial Overview
126.96.36.199. Product Portfolio
188.8.131.52. SWOT Analysis
184.108.40.206. Strategic Overview
14.3.11. Cellecta, Inc.
220.127.116.11. Company Overview
18.104.22.168. Financial Overview
22.214.171.124. Product Portfolio
126.96.36.199. SWOT Analysis
188.8.131.52. Strategic Overview
14.3.12. Agilent Technologies
184.108.40.206. Company Overview
220.127.116.11. Financial Overview
18.104.22.168. Product Portfolio
22.214.171.124. SWOT Analysis
126.96.36.199. Strategic Overview
14.3.13. Applied StemCell, Inc.
188.8.131.52. Company Overview
184.108.40.206. Financial Overview
220.127.116.11. Product Portfolio
18.104.22.168. SWOT Analysis
22.214.171.124. Strategic Overview
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