Biomarkers play a vital role in disease detection and subsequent treatments. Biomarkers are often measured and evaluated to examine normal biological processes, pathogenic processes, or pharmacologic responses following a therapeutic intervention. Biomarkers are used in many scientific fields such as medicine, geology and astrobiology, cell biology, ecotoxicology, and others. These substances are mainly utilized with the help of specific methodologies, which together constitute the biomarker detection systems. As each of the fields described here are undergoing rampant advancement, the use of biomarker systems has shot up splendidly in recent times.
Of all these sectors, the field of medicine has witnessed maximum use of biomarker detection systems. Widespread research is going on in this context mainly with respect to enhancing technologies, by which identification of particular diseases, genes, cells, and other organic components can be easily undertaken. Evaluation of cardiovascular health, monitoring electric currents, and testing of natural metabolites are few important applications of using biomarker detection systems.
However, due to various technical difficulties, the potential of the relevant systems is not explored completely. Nonetheless, this picture is soon anticipated to change as there are several players operating in the global biomarker detection system, who are expected to introduce highly advanced biomarker detection systems during in the upcoming years.
Biological marker or commonly known as a biomarker is a characteristic which is found in tissues, bodily fluids or body. A biomarker is a biological characteristic that can be measured as an indicator of normal, abnormal pathological process or a response to therapeutic intervention. The quantitative measurement of the biomarkers is done by Biomarker Detection Devices. Biomarker helps in prediction, cause, diagnosis, regression, progression, and outcome of the disease. Biomarkers can be specific cells, gene, gene products, hormones, enzymes, proteins and particular characteristics change the biological structure. Biomarker detection used in broad therapeutic areas such as neurological disease, metabolic disorders, and Immune deregulation predominantly the field of Oncology.
The Biomarker detection systems use a special type of plates called as microtitre plate or microwell plate or microtitre plate or PCR plate. The plates are used as small test tube well which is arranged in a rectangular matrix (2:3) and available in three sizes 96, 384 and 1536. These plates may or may not be pretreated. The assay based biological, chemical or physical reactions in the microwell plates which are analyzed by a detector system usually called Microplate readers. Technological advancement in the field of biomarker detection systems led to the development of more compact and user interactive Microplate readers. They can be either automatic or semi-automatic Microplates readers. Some modern ultrasensitive biomarker detection systems allow a user to run prepackaged reagent kits, multiplex detection up to six analytes and flexibility to design to detect protein, nucleic acid biomarkers with no need of analytical extraction, amplification, and PCR. The modern biomarker detection system is time-saving and can reliably and accurately quantify low abundance biomarkers (in femtogram/ml) devices as compared to the older immunoassay detection systems. It functions on the principle of absorbance, luminescence, fluorescence and other spectrophotometric technique. Biomarker detection system measures absorbed light by the biomarkers (different biomarkers have different absorbance based on the structure and molecular weight).
Biomarker Detection Systems Market: Drivers and Restrains
The paradigm shift of research institutes and biotechnological companies is leading to the growth of the biomarker detection systems market. The new research and developments in the area of biomarker detection systems led to addition of a bunch of new interesting features to the existing devices making it more reliable and accurate than the existing devices available in the market. Automation in biomarker detection systems overcame the hurdles which were faced by the traditional devices thus making it more flexible. New biomarker detection systems are multimodal which allows the user to perform many assays at the same time in a single instrument. The multimodal biomarker detection systems can use different modes to recognize, identify and quantify the different type of biomarker. All the above factors ultimately drive the growth of the biomarkers detections systems.
Due to the new cheap alternatives of the biomarker detection system available in the market will act as an impediment to the growth of the market.
Biomarker Detection Systems Market: Segmentation
The global Biomarker Detection Systems market has been classified on the basis of product type, end user and geography.
Based on product type, the biomarker detection systems market divided into following:
- Multimode microplate reader
- Single mode microplate reader
- Absorbance microplate reader
- Fluorescence microplate reader
- Luminescence microplate reader
Based on end user, the biomarker detection systems market divided into following:
- Diagnostic centers
- Biotechnology companies
- Academic Research Institutions
Biomarker Detection Systems Market: Overview
The biomarker detection systems market is segmented based on the product type and end user. Based on product type, the biomarker detection systems market is segmented into single mode microplate readers and multimode microplate readers. The single mode microplate readers are further divided into absorbance microplate reader, fluorescence microplate reader and luminescence microplate reader. The multimode microplate readers segment is expected to see a surge due to its multiple uses. Based on the end user veterinary procedure lights market is segmented into, hospitals, clinics, diagnostic centers, biotechnology companies and academic research institutions. Microplate readers are gaining popularity due to its flexibility, functionality and speed. They form very important part of the diagnostic centers.
Biomarker Detection Systems: Regional Overview
Region wise, the global veterinary procedure lights market is classified into regions namely, North America, Latin America, Western Europe, Eastern Europe, Asia-Pacific, Japan, Middle East and Africa. Due to the strong presence of key players in these regions North America is dominating in the global microplate reader market. Mainly the US occupies the significant share in North America due to the high acceptance of microplate readers. It followed by the Europe and Asia-pacific regions. The Latin America will also see a steady growth of biomarker detection systems. A major shift towards automation of the key laboratory instruments is driving the growth in these regions. The growth in the Middle East and Africa is quite low as compared to the other regions.
Biomarker Detection Systems Market: Key Players
Some of the key players in global biomarker detection systems market are Quanterix, Merck, BioTek Instruments Inc., Biocompare, Thermo Fischer Scientific Inc., Tecan Trading AG, BMG Labtech, Bio-Rad Laboratories, Corning Incorporated, PerkinElmer Inc., Molecular Devices LLC, Awareness Technology Inc., Hidex Oy, Agilent Technologies and others.
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