Calprotectin Serum Immunoassay Market Outlook 2025 to 2035
The Calprotectin Serum Immunoassay Market is projected to rise from USD 148.9 Million in 2025 to USD 315.6 Million by 2035, growing at a CAGR of 7.8%. These tests are used to detect intestinal inflammation and inflammatory bowel diseases (IBD) with high accuracy, supporting early diagnosis.

| Metric | Value |
|---|---|
| Calprotectin Serum Immunoassay Market Estimated Value in (2025 E) | USD 148.9 million |
| Calprotectin Serum Immunoassay Market Forecast Value in (2035 F) | USD 315.6 million |
| Forecast CAGR (2025 to 2035) | 7.8% |
According to the latest research by Fact.MR, calprotectin serum immunoassay market is set to experience a steady growth during the year 2021-2031. Calprotectin is serum which is secreted by neutrophil which is a type of White Blood Cell or WBC. With various researches finding applications in management of various diseases, this market will see a steady growth over the forecast period of 2021-2031.
| Countries | CAGR |
|---|---|
| Germany | 8.3% |
| United States | 7.9% |
| France | 7.5% |
| Japan | 7.1% |
What is driving the demand for Calprotectin Serum Immunoassay Market?
The most common driver for this market is its application in inflammatory bowel syndromes like crohn disease ad ulcerative colitis. It can be called as an inflammatory marker and hence is seen as a biomarker in detection of various diseases like CVD, pulmonary fibrosis, rheumatoid arthritis, etc. as this serum is secreted at the site of any inflammation in the body.
This diversified presence makes calprotectin a very formidable driver in this market as immunoassays can be developed and swift detection of various diseases can be done giving the whole market a drastic boost. Furthermore, the rising cases of inflammatory bowel syndrome are likely to boost the global market demand.
According to studies published in journals like BMJ, BMC and Bentham Science Publishers, an increase in calprotectin serum was noticed in subjects with aortic aneurysm, pulmonary fibrosis, rheumatoid arthritis. This suggests that developing immunoassays for detection of the serum for these specific diseases will drive the market upwards.
A study exploring the use of this serum’s potential use in finding out metabolic complication was published in 2018 in Journal – Annals of Nutrition and Metabolism. Researchers here looked at Calprotectin as a potential biomarker of obesity and its metabolic complications.
Calprotectin serum as COVID19 severity biomarker –
A very recent study published in Expert Review of Clinical Immunology, studied correlation between calprotectin serum and COVID19. Samples from COVID19 positive patients were taken and after blood analysis, the levels of calprotectin were directly compared with levels neutrophils (type of WBC), fibrinogen and D-dimer.
These parameters were helpful in determining the severity of the viral infection in that individual. This novel application of calprotrectin serum as biomarket for COVID19 severity will help in better understanding this constant mutating virus and better management can be done. With pandemic far from over, the calprotectin serum immunoassay market is sure to experience a boost in this regards.
U.S and Canada Calprotectin Serum Immunoassay Market
Advanced infrastructure with suitable spending on the research and development as well as constant technological improvements have made US the most lucrative market in this field. The presence of key companies like Thermo-Fisher Scientific, Agilent Technologies, Inc. will play an important role in bringing novel innovation in this market.
Europe Calprotectin Serum Immunoassay Market
Awareness amongst the Europeans about diagnostic testing can be increasing as according to European Heart Network, 45% of all deaths in Europe occur due to CVD or cardiovascular disease. Also COVID19 cases have surged exponentially during the pandemic. Both of the above mentioned diseases and their potential application in using calprotectin serum as inflammation marker will certainly give boost to the development of immunoassays in this region. This will in turn boost this market during the forecast period.
Who are the key manufacturing supplying companies in Calprotectin Serum Immunoassay Market?
Key manufacturers and suppliers in the market are:
- Eurospital
- Calpro
- Thermo-Fisher Scientific
- Buehlmann
- Biotec
- Abbott Laboratories
- F.Hoffmann-La Roche
- Siemens AG
- Danaher Corporation
- Diasorin SPA
- Sysmex Corporation
- Biomerieux SA
- QIAGEN
- Agilent Technologies, Inc.
Calprotectin Serum Immunoassay Market Report Highlights
- Detailed overview of parent market
- Changing market dynamics in the industry
- In-depth market segmentation
- Historical, current and projected market size in terms of volume and value
- Recent industry trends and developments
- Competitive landscape
- Strategies of key players and products offered
- Potential and niche segments, geographical regions exhibiting promising growth
- A neutral perspective on market performance
- Must-have information for market players to sustain and enhance their market footprint
Key Segments –
-
By Assay Type:
- ELISA (Enzyme linked Immunosorbent Assay)
- Enzyme fluoroimmunoassay
- Quantitative immune-chromatography
-
By Application:
- Crohn Disease
- Ulcerative colitis
-
By End User:
- Hospitals
- Diagnostic Laboratories
- Ambulatory Care Centres
- Research Institutions
-
By Region:
- North America
- Latin America
- Europe
- South Asia
- East Asia
- Oceania
- Middle East & Africa
The report is a compilation of first-hand information, qualitative and quantitative assessment by industry analysts, inputs from industry experts and industry participants across the value chain. The report provides in-depth analysis of parent market trends, macro-economic indicators and governing factors along with market attractiveness as per segments. The report also maps the qualitative impact of various market factors on market segments and geographies.
NOTE: Although care has been taken to maintain the highest levels of accuracy in reports, recent market/vendor-specific changes may take time to reflect in the analysis.
- Frequently Asked Questions -
Which country will spearhead the growth in Calprotectin Serum Immunoassay Market?
The United States is the most profitable market in this industry.
What factors are driving the Calprotectin Serum Immunoassay Market?
The most prevalent driving force for this market is its use in inflammatory bowel disorders such as Crohn's disease and ulcerative colitis.
Which are the top 5 players in Calprotectin Serum Immunoassay Market?
Eurospital, Calpro, Thermo-Fisher Scientific, Buehlmann and Biotec are the top 5 players in Calprotectin Serum Immunoassay Market.