Immunoprecipitation Market

Immunoprecipitation Market Outlook (2023 to 2033)

Expanding steadily at 5.8% CAGR over the next ten years, the global immunoprecipitation market size is projected to increase from a size of US$ 656 million in 2023 to US$ 1.16 billion by the end of 2033.

One of the most popular techniques used for identifying and purifying antigens is immunoprecipitation. A specific antibody attached to a solid substrate, such as magnetic particles or agarose glue, is used in this approach to separate a particular antigen from a mixture. The procedure is widely used to separate proteins and other macromolecules from cell or tissue lysates for later detection by western blotting and other test methods.

The expanding opportunities for government and non-government entities to support and invest in research on next-generation DNA sequencing and genomics are estimated to supplement the demand for immunoprecipitation over the coming years. Sales of immunoprecipitation kits are also projected to rise as a result of expanding use of immunoprecipitation solutions in the diagnosis of malignancies, cardiovascular illnesses, and central nervous system disorders.

• Immunoprecipitation accounts for 10% share of the global protein purification market in 2023.

Surging investments in life science R&D, advancements in immunoprecipitation protocols, growing demand for cancer immunotherapy research, and significant advances in genetic research are other key factors that could widen the scope of immunoprecipitation applications over the next ten years. High adoption of personalized medicine and stem cell therapies is also set to favour market development through 2033.

Report Attributes	Details
Immunoprecipitation Market Size (2023)	US$ 656 Million
Projected Market Value (2033F)	US$ 1.16 Billion
Global Market Growth Rate (2023 to 2033)	5.8% CAGR
Reagents Market Share (2023)	45%
China Market Growth Rate (2023 to 2033)	>8% CAGR
Key Companies Profiled	Merck KGaA Takara Bio Inc. Abbkine Scientific Co. Ltd. Abcam PLC BioLegend Bio-Rad Laboratories Cell Signaling Technology Inc. Thermo Fisher Scientific Geno Technology Inc. GenScript Biotech Corporation Rockland Immunochemicals Inc.

How Can Start-ups Successfully Penetrate the Immunoprecipitation Market?

“Introducing Modern Genetic Techniques Essential to Stand Out in the Global Landscape”

Innovative activities to enhance genomic research and improve the healthcare system are the primary focus of new businesses that are entering the immunoprecipitation space. Upcoming immunoprecipitation providers are highly focused on introducing modern genetic techniques, investing in genomic-based research activities, and entering into collaborations with researchers to make a space for themselves in this market.

• The whole human genome assembly's preliminary results were published by the T2T Consortium. Researchers described the 'telomere-to-telomere' (T2T) version of the whole human reference genome, including the genome sequence, genetic variants, epigenetics, expression, and other findings.

Start-ups can benefit by learning more about various aspects such as local supply, pricing trends, product standards, safety regulations, and new developments that have been discussed extensively in this immunoprecipitation industry study by skilled analysts at Fact.MR, a market research and competitive intelligence provider.

What Could Hurt the Profitability of Immunoprecipitation Providers?

“Availability of Alternative Protein Isolation Technologies and Antibody Contamination”

A frequent problem with co-immunoprecipitation is antibody contamination. Several subsequent processes, such as the western blot, add new bands to the gel. The light-chain and heavy-chain antibodies that co-eluted with the protein complex as a result of contamination frequently obstruct the process of protein identification. Therefore, such factors are hampering the demand for immunoprecipitation solutions.

Availability of alternative protein isolation technologies is restraining the growth of the immunoprecipitation market. Market expansion may be further hampered by worries about the caliber of research antibodies. The general applicability of this test may be restricted by sample size restrictions and variations in lipid content, which is impeding market revenue.

Country-wise Insights

Why Do Immunoprecipitation Companies See the United States as a Key Market?

“High Demand for DNA Immunoprecipitation Techniques”

High investments in the R&D of novel genetic technologies and treatments by public and private companies in the United States are projected to bolster market growth going forward. The expanding life sciences industry is encouraging the widespread use of immunoprecipitation technologies, improving protein purification processes. Technological innovations in immunoprecipitation systems are also projected to favour demand for immunoprecipitation software and immunoprecipitation data analysis over the coming years.

Huge demand for DNA immunoprecipitation solutions, the presence of key market players, the rapid adoption of protein complex immunoprecipitation techniques, and the surging use of immunoprecipitation in cancer research applications are other prospects that attract immunoprecipitation companies to the United States.

How is the Market for Immunoprecipitation Evolving in China?

“Greater Government Support and Investments in Healthcare Industry”

Just like most other Asian countries, the focus on healthcare infrastructure development in China is increasing as the patient pool of the country continues to expand. High incidence of chronic disorders, expanding senescent population, and growing use of immunoprecipitation crosslinking solutions are other factors influencing market growth in the country.

• Demand for immunoprecipitation in China is forecasted to rise at an impressive CAGR of more than 8% from 2023 to 2033.

Sales of immunoprecipitation solutions in China are being driven by a strong awareness of precision pharmaceuticals or genetic disorder therapies, a surge in biotechnology research activities, and greater government support and investments in the healthcare industry.

What’s Driving Demand for Immunoprecipitation in European Countries?

“Growing Research Activities Involving Protein Interactions and Proteomics”

Investments in proteomics research in European countries have been increasing over the past few years and immunoprecipitation has been proven to be the best available method to study and analyze proteins. Rising demand for protein characterization, growing use of immunoprecipitation in drug discovery, and supportive government initiatives to promote advancements in immunoprecipitation technologies are other prospects that create opportunities for immunoprecipitation companies in European countries such as Germany, France, Italy, and the United Kingdom.

Category-wise Insights

Why Should Companies Focus on Chromatin Immunoprecipitation?

“Growing Use of Chromatin Immunoprecipitation in Genomic Studies”

Based on type, the immunoprecipitation market is classified into RNA immunoprecipitation, co-immunoprecipitation, chromatin immunoprecipitation, and individual protein immunoprecipitation.

The chromatin immunoprecipitation segment is expected to rise at a significant CAGR over the forecast period. Chromatrap technology enables data accuracy and offers quick analysis without pipetting concerns. This makes it possible for researchers to simultaneously evaluate several antibodies and gene targets.

Chromatin immunoprecipitation is a specific aspect of immunoprecipitation techniques that is used to look into the areas of the genome that are related to a target DNA-binding protein or to pinpoint the precise proteins linked to a given region of the genome. In epigenetics research, chromatin immunoprecipitation is frequently employed. Top market players also participate in research projects to provide better chromatin immunoprecipitation procedures, which promote segment growth.

One of the key factors influencing the investigated segment over the forecast period is the widespread use of chromatin immunoprecipitation in numerous genomic studies. Whereas, use of individual IP in various research projects is expected to increase over the coming years due to its growing applications in the investigation of protein-protein interactions, antigen detection, and antigen quantity estimation.

Which Component Accounts for High Global Revenue Generation?

“Sales of Reagents to Pay Off Bigtime in Future”

The immunoprecipitation market is categorized into accessories, kits, and reagents based on components.

• At present, reagent sales account for around 45% share of the global market.

One of the main factors promoting the demand for reagents is the rising popularity of reagents for the separation and purification of antigens. The surging demand for agarose and magnetic beads among research laboratories for protein purification applications is also slated to benefit shipments of reagents over the next ten years.

Why are Immunoprecipitation Providers Targeting Academic & Research Institutes?

“Extensive Research in Molecular Biology & Genetics”

By end user, the immunoprecipitation market is divided into pharma & biopharma companies, academic & research institutes, and contract research organizations.

Increasing government funding for molecular biology & genetics has pushed academic and research institutes to launch R&D initiatives for these interests thereby driving immunoprecipitation kit sales in academic & research institutes. The trend of penning new international research collaborations between academic institutions and research facilities is also anticipated favour market development in the long run.

Competitive Landscape

Leading immunoprecipitation providers are focusing on mergers, acquisitions, collaborations, and partnerships to expand their business scope and maintain their market share in the global competitive landscape over the study period.

• In September 2020, REMD Biotherapeutics, a biotechnology company headquartered in California, and GenScript ProBio, a leader in molecular cloning, announced the expansion of their collaboration. REMD acquired the global rights for the development and commercialization of a bispecific antibody from GenScript ProBio.

Key Segments of Immunoprecipitation Industry Research

• By Type :

  • Individual Protein
  • Chromatin
  • Co-immunoprecipitation
  • RNA

• By Component :

  • Reagents
  • Kits
  • Accessories

• By End User :

  • Academic & Research Institutes
  • Pharma & Biopharma Companies
  • Contract Research Organizations

• By Region :

  • North America
  • Latin America
  • Europe
  • APAC
  • MEA