Immunoprecipitation Market

Immunoprecipitation Market Outlook (2022-2027)

The global demand for immunoprecipitation is anticipated to accelerate at a CAGR of 6% from 2022 to 2027. At present, the global immunoprecipitation market is valued at US$ 620 million and is projected to reach a market size of US$ 830 million by the end of 2027.

Demand for reagents is forecasted to rise at a CAGR of 6.2% through 2027 due to the extensive use of antibodies, buffers, and beads for various immunoprecipitation techniques.

“Surging Need to Identify Antigens Associated with Autoimmune Illnesses”

One of the most popular techniques used for identifying and purifying antigens is immunoprecipitation. A specific antibody attached to a solid substrate, such as magnetic particles or agarose glue, is used in this approach to separate a particular antigen from a mixture. The procedure is widely used to separate proteins and other macromolecules from cell or tissue lysates for later detection by western blotting and other test methods.

The rise in research activities and the surging need to identify antigens that are associated with autoimmune illnesses are key factors that are anticipated to boost market expansion over the coming years. Increased knowledge of tailored therapies and the global uptick in biotechnology research are also aiding market growth. Growing focus on biomarker detection systems is projected to present lucrative opportunities in the immunoprecipitation market over the coming years.

Market progress is also attributed to the expanding opportunities for government and non-government entities to support and invest in research on next-generation DNA sequencing and genomics. Last but not the least, the market for immunoprecipitation testing is evolving as a result of expanding use of immunoprecipitation solutions in the diagnosis of malignancies, cardiovascular illnesses, and central nervous system problems.

At present, immunoprecipitation accounts for around 10% share of the global protein purification market.

“New Market Players Focused on Introducing Modern Genetic Techniques”

Innovative activities to enhance genomic research and improve the healthcare system are the primary focus of new businesses that are entering this market space. New market entrants are highly focused on introducing modern genetic techniques, investing in genomic-based research activities, and entering into collaborations with researchers to make a space for themselves in this market.

• The whole human genome assembly's preliminary results were published by the T2T Consortium. Researchers described the 'telomere-to-telomere' (T2T) version of the whole human reference genome, including the genome sequence, genetic variants, epigenetics, expression, and other findings.

Report Attributes	Details
Immunoprecipitation Market Size (2022)	US$ 620 Million
Projected Market Value (2027)	US$ 830 Million
Global Market Growth Rate (2022-2027)	6% CAGR
Market Share of Reagents	45%
Share in Protein Purification Market (2022)	10%
Key Companies Profiled	Merck KGaA Takara Bio Inc. Abbkine Scientific Co. Ltd. Abcam PLC BioLegend Bio-Rad Laboratories Cell Signaling Technology Inc. Thermo Fisher Scientific Geno Technology Inc. GenScript Biotech Corporation Rockland Immunochemicals Inc.

Which are the Prominent Drivers for the Immunoprecipitation Market?

“Recent Developments in Immunoprecipitation Boosting Market Value”

The market is driven by an increase in research activities in the life sciences sector. Market expansion is supported by technological advancements in immunoprecipitation methods. Collaborations between organizations and researchers have made a substantial contribution to the expansion of the life sciences industry.

New methods for prospective biological remedies have been developed as a result of academic scientific advances in the fields of cellular and genetic therapies. The range of new findings is expanding as more study is being done in the fields of genetics, cancer immunotherapy, and microbiome.

Modern genetic approaches have led to ongoing research and development (R&D) for illnesses investigation, drug development, and planning of individualized treatment. Numerous government and regulatory agencies are launching strategic initiatives to support genetic research and improve the healthcare system.

The Chromatrap Immunoprecipitation (ChIP) technology is a bead-free way of carrying out chromatin immunoprecipitation as a result of advancements in the chromatin immunoprecipitation process. The industry is estimated to have considerable growth due to epigenetic advances made possible by ChIP-seq.

“Growing Significance of Stem Cell Therapy in Development of Cell-based Treatments”

The global immunoprecipitation market is projected to be driven by the increasing number of cancer cases and the demand for precision medications. There is a surging need for immunoprecipitation to investigate the disease mechanism and develop disease-focused drugs due to the rise in autoimmune disorders.

Immunoprecipitation testing help researchers understand interactions in cancer patients because tumor cells that resist treatment exhibit dynamic protein-protein interactions. As a result, market expansion is anticipated to be fueled by the rising cancer burden.

Age-related disorders and the increasing elderly population are likely to fuel market value. The necessity for precision medications to treat orthopedic and cardiovascular disorders is also forecasted to drive growth in the worldwide immunoprecipitation industry.

A further aspect that is predicted to propel the global immunoprecipitation market is the growing significance of stem cell therapy in the development of cell-based treatments. New studies and procedures have been developed as a result of advances in genomics, such as the change of the genome by transforming cells.

What Can Limit the Demand for Immunoprecipitation Methods?

“Availability of Alternative Protein Isolation Technologies and Antibody Contamination”

A frequent problem with co-immunoprecipitation is antibody contamination. Several subsequent processes, such as the western blot, add new bands to the gel. The light-chain and heavy-chain antibodies that co-eluted with the protein complex as a result of contamination frequently obstruct the process of protein identification. Therefore, such factors are hampering the demand for immunoprecipitation solutions.

The availability of alternative protein isolation technologies is restraining the growth of the immunoprecipitation market. Market expansion may be further hampered by worries about the caliber of research antibodies.

The general applicability of this test may be restricted by sample size restrictions and variations in lipid content, which is impeding market revenue.

What Makes North America a Leading Regional Market for Immunoprecipitation?

“High Emphasis on Customized Medicines in North America”

North America accounts for the highest share of the immunoprecipitation market due to a rise in R&D investments by pharmaceutical and biotechnology firms, a high emphasis on customized medicines, and growing partnerships between pharmaceutical firms and premier academic institutions.

Other key reasons supporting market expansion in the region include the extensive usage of advanced immunoprecipitation techniques in genome analysis and DNA-protein interactions.

Country-wise Insights

Why is the U.S. Immunoprecipitation Market Exhibiting High Growth Opportunities?

“High Demand for DNA Immunoprecipitation Techniques in the United States”

The expanding life sciences industry is encouraging the widespread use of immunoprecipitation technologies, improving protein purification processes. Technological innovations in immunoprecipitation systems are another factor boosting market revenue.

Huge demand for DNA immunoprecipitation solutions, the presence of key market players, and the rapid adoption of protein complex immunoprecipitation techniques are driving market growth in the U.S.

How is the Market for Immunoprecipitation Evolving in China?

“Greater Government Support and Investments in Healthcare Industry”

The immunoprecipitation market in China is expected to evolve at a CAGR of 9% from 2022 to 2027 because of the growing disposable income, infrastructure development, and high demand for immunoprecipitation crosslinking solutions.

Market expansion in China is being driven by a strong awareness of precision pharmaceuticals or genetic disorder therapies, a surge in biotechnology research activities, and greater government support and investments in the healthcare industry.

Category-wise Insights

Which Immunoprecipitation Type is Most Widely Used across the World?

“Growing Usage of Chromatin Immunoprecipitation in Numerous Genomic Studies”

Based on type, the immunoprecipitation market is classified into RNA immunoprecipitation, co-immunoprecipitation, chromatin immunoprecipitation, and individual protein immunoprecipitation.

The chromatin immunoprecipitation segment is expected to rise at a significant CAGR over the forecast period. Chromatrap technology enables data accuracy and offers quick analysis without pipetting concerns. This makes it possible for researchers to simultaneously evaluate several antibodies and gene targets.

Chromatin immunoprecipitation is a specific aspect of immunoprecipitation techniques that is used to look into the areas of the genome that are related to a target DNA-binding protein or to pinpoint the precise proteins linked to a given region of the genome. In epigenetics research, chromatin immunoprecipitation is frequently employed. Top market players also participate in research projects to provide better chromatin immunoprecipitation procedures, which promote segment growth.

One of the key factors influencing the investigated segment over the forecast period is the widespread use of chromatin immunoprecipitation in numerous genomic studies.

Whereas the use of individual IP in various research projects is expected to increase over the coming years due to its growing applications in the investigation of protein-protein interactions, antigen detection, and antigen quantity estimation.

Why Do Reagents Account for a Major Market Share?

“Rising Popularity of Reagents for Separation and Purification of Antigens”

The immunoprecipitation market is categorized into accessories, kits, and reagents based on components. Reagents account for 45% share of the global market.

One of the main drivers for segment growth is the rising popularity of reagents for the separation and purification of antigens. The segment expansion is attributed to the surging demand for agarose and magnetic beads among research laboratories for protein purification.

Why is Demand for Immunoprecipitation Techniques Surging in Academic & Research Institutes?

“Extensive Research in Molecular Biology & Genetics Driving Demand for Immunoprecipitation Systems in Academic & Research Institutes”

By end user, the immunoprecipitation market is divided into pharma & biopharma companies, academic & research institutes, and contract research organizations.

Extensive research in molecular biology & genetics and increasing government funding for R&D initiatives are driving the demand for immunoprecipitation techniques in academic & research institutes. The expansion of this segment is being supported by expanding international research collaborations between academic institutions.

Competitive Landscape

Key manufacturers are involved in a range of strategic efforts, including the introduction of new products, research activities, and geographic expansion.

For instance :

• GenScript Biotech Corporation and REMD Biotherapeutics Inc. entered into a strong partnership to develop bispecific antibody-based novel immunotherapy medications.
• Thermo Fisher Scientific established a new bioprocess design center in Shanghai to work with biologic researchers and provide the best bioprocessing technologies.

Segments of Immunoprecipitation Industry Research

• By Type :

  • Individual Protein 
  • Chromatin 
  • Co-immunoprecipitation
  • RNA 

• By Component :

  • Reagents
  • Kits
  • Accessories

• By End User :

  • Academic & Research Institutes
  • Pharma & Biopharma Companies
  • Contract Research Organizations

• By Region :

  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East & Africa