Lyophilization Market Analysis By Product Type (Freeze Dryers & Accessories) By Scale of Operation (Pilot-scale, Laboratory-scale & Industrial-scale) By End-User and By Region – Global Market Insights 2022 to 2032
Lyophilization Market Outlook (2022-2032)
In 2021, the global lyophilization market was valued at US$ 926.1 million and is anticipated to reach US$ 2.3 billion by 2032, expanding at a high 8.8% CAGR over the 2022-2032 time frame.
Worldwide revenue from lyophilization accounts for around 16% share of the global cryopreservation market.
Lyophilization Market Size (2021)
US$ 926.1 Million
Estimated Market Value (2022)
US$ 988.8 Million
Forecasted Market Value (2032)
US$ 2.3 Billion
Global Market Growth Rate (2022-2032)
Share of Top 5 Countries
Key Market Players
As per detailed industry analysis by Fact.MR, a market research and competitive intelligence provider, the freeze dryers product segment dominated the market accounting for 67.7% market share, and the segment is expected to surge ahead at a CAGR of 9.6% through 2032.
Industrial-scale operations accounted for 40.6% market share and held a market value of US$ 375.6 million at the end of 2021.
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Lyophilization Demand Analysis (2012-2021) Vs. Market Outlook (2022-2032)
The global lyophilization market expanded at a CAGR of 4.9% over the last nine years (2012-2021) owing to rising demand for the lyophilization process for use in biopharmaceutical as well as pharmaceutical products.
Several benefits associated with the lyophilization process and technical advancements in freeze-drying equipment are major factors driving the demand for lyophilization, globally.
The lyophilization process is beneficial for extending the shelf life of pharmaceutical drugs and biopharmaceutical products such as antibodies, vaccines, peptides, and others. The lyophilization process helps in the removal of moisture by putting the product under three interconnected steps - freezing, primary drying, and secondary drying.
This not only helps in stabilizing pharmaceutical formulations but also broadens the capability of temperature tolerance in these products.
Technical advancements have boosted the lyophilization market. Since temperature is a crucial parameter for various pharmaceuticals and biopharmaceuticals, freeze dryers have been developed that can easily optimize the shelf temperature and chamber pressure so that the quality of the product is not hampered while it is below its critical point. These freeze dryers maximize the sublimation rate as well, thereby enhancing the stability of compounds.
Fact.MR predicts the global lyophilization market to expand at a high CAGR of 8.8% over the forecast period (2022-2032).
What is Mainly Driving Demand for Lyophilization?
“Rising Investments in Research and Development Related to Lyophilization”
Since there are biopharmaceutical products that cannot be marketed without undergoing the lyophilization process, the need for investments in the research and development of lyophilization is rising day by day.
- LyoHUB is an advanced lyophilization technology hub that aims at advancing science and technology focusing on freeze-drying or lyophilization.
Manufacturers are even partnering with this hub to focus on advancements in lyophilization techniques.
- For instance, in 2015, Millrock Technology partnered with LyoHUB to carry out advancements related to the lyophilization process.
The attention put towards advancements in lyophilization products and processes is boosting the growth of the overall lyophilization market.
“Rise in Number of Lyophilization Service Providers”
Increasing demand for lyophilization services is creating greater opportunities for the manufacturers of freeze dryers and their accessories. Different organizations offer services for successful pharmaceutical drug development and manufacturing processes. These include contract development and manufacturing organizations (CDMOs) and contract manufacturing organizations (CMOs).
- For instance, LSNE Contract Manufacturing is a CMO that helps various pharmaceutical companies produce commercial products. It offers manufacturing services that comprise aseptic fill-finish manufacturing and lyophilization, bulk lyophilization, non-aseptic fill-finish & lyophilization, and others.
What’s Restraining the Lyophilization Market from Reaching its Full Potential?
“High Costs Associated with Lyophilization Setup”
The cost of freeze-drying equipment is quite high, and this restricts small- and medium-scale companies from acquiring such equipment to carry out the lyophilization process.
These higher costs associated with lyophilization setups are a major factor that restricts the growth of the market to some extent.
What is the U.S. Market Stance for Lyophilization?
“Ever-increasing Consumption of Freeze-dried Food Products”
The U.S. accounted for around 91.6% of the North American lyophilization market share in 2021 owing to the trend of the general population preferring freeze-dried food products and an increase in the number of organizations offering lyophilization services, as enlisted by the FDA.
Due to the increasing consumption of freeze-dried vegetables, fruits, and food, demand for lyophilizers in the food processing industry is rising. It provides stability to food products, thereby increasing their shelf life.
- Jubilant HollisterStier is a contract manufacturing organization in the U.S. that offers specialized facilities for lyophilization. It focuses on investing in new lyophilizers to broaden its portfolio.
Will Germany Be a Lucrative Market for Lyophilization Providers?
“Market to Be Driven by Fast-paced Growth of the F&B Industry”
Germany accounted for 22.9% share of the European lyophilization market in 2021.
- As per the Germany Trade and Invest (the economic development agency of the Federal Republic of Germany), the industry of food and beverages in Germany is the largest in the European region.
Dramatic growth of the food industry demands lyophilization techniques so that companies can provide high-quality freeze-dried products.
Lyophilization not only increases the shelf life of food products but also facilitates easier and more convenient storage. This leverages the logistics of these food industries, thereby making Germany’s food and beverage industry a top contender in the European region.
The presence of various manufacturers increases the availability of freeze dryers and their accessories in Germany. Manufacturers such as Zirbus Technology GmbH, HOF Sonderanlagenbau GmbH, Martin Christ Gefriertrocknungsanlagen GmbH and GEA Group have their head offices in country.
Which Factors are Fueling Demand for Lyophilization Solutions in China?
“Rapid Growth of Pharmaceutical Industry”
China accounted for 43.6% of the East Asia lyophilization market share in 2021.
Increasing awareness about the advantages of lyophilized products has helped in driving the demand for lyophilizers and freeze dryers in China.
The growing number of domestic pharmaceutical companies is boosting the lyophilization market within the country because lyophilization acts as a stability tool for the pharmaceutical and food processing industries.
How is the Lyophilization Market Evolving in India?
“Steady Growth of the Food Processing Industry”
India accounted for 48.6% of the South Asia lyophilization market at the end of 2021.
When it comes to the food processing industry, India is one of the known industries which is looked upon for high-quality food processing products.
- For instance, as per findings by the National Investment Promotion and Facilitation Agency, the food processing sector was reported to grow at an average annual growth rate of approximately 11.18% from 2015-2020 in India.
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Why is Demand for Freeze Dryers Gaining Huge Traction?
“Rise in Sales of Lyophilized Products”
The freeze dryers segment held the highest market share of 67.7% in 2021. This segment is expected to expand at 9.6% CAGR over the forecast period.
This high traction is being influenced by increasing research & development activities on lyophilization techniques.
Furthermore, the advantages offered by lyophilizers and freeze dryers are profitable for researchers in pharmaceutical, biopharmaceutical, and food processing industries. This makes the freeze dryers segment the most lucrative for the years ahead.
Which Scale of Operation is Driving Demand Growth for Lyophilization?
“Surge in Demand for Pharmaceutical & Food Processing Products”
Industrial-scale operations accounted for 40.6% market share in 2021.
Industrial-scale operations are the biggest platform where freeze-drying equipment is utilized for lyophilization purposes. Manufacturing is done at the industrial level; therefore, demand for freeze dryers is more at the industrial scale of operations.
Key manufacturers of lyophilizers and their accessories are actively focusing on the expansion of their businesses across various locations in the world. Market players are also focusing on innovation by launching new products as a strategy to maintain their position in the global lyophilization market.
Apart from this, collaborations and partnerships are a major promotional strategy carried out by different industry players.
- In 2020, Martin Christ Gefriertrocknungsanlagen GmbH, and Elementar Americas, a technology leader in elemental analysis, collaborated to support their sales and services in the Americas.
- In June 2021, SP Industries Inc. launched the SP Hull LyoStar® 4.0 R&D freeze dryer to support freeze-dry cycle development, optimization, and process scale-up.
- In April 2022, Azbil expanded its operations by opening a new factory in China, through its production base in China called Azbil Control Instruments (Dalian) Co., Ltd.
Similarly, recent developments related to companies operating in the lyophilization market have been tracked by the team at Fact.MR, which are available in the full report.
Key Segments Covered in Lyophilization Industry Research
By Product Type :
- Freeze Dryers
- Tray-style Dryers
- Rotary Freeze Dryers
- Manifold Freeze Dryers
- Drying Chambers
- Vacuum Systems
- CIP (Clean-in-place) Systems
- Other Accessories
- Freeze Dryers
By Scale of Operation :
By End User :
- Biopharmaceutical Companies
- Food and Beverage Companies
- Academic and Research Institutes
- CROs & CMOs
- Research Laboratories
By Region :
- North America
- Latin America
- East Asia
- South Asia
- Middle East and Africa (MEA)
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