Carbon Dioxide Incubators Market

Carbon Dioxide Incubators Market Outlook (2025 to 2035)

The global carbon dioxide incubators market is expected to reach USD 983.3 million by 2035, up from USD 384.9 million in 2024. During the forecast period (2025–2035), the industry is projected to expand at a CAGR of 8.9%

Carbon dioxide incubators are basic equipment used in cell culture studies and are designed to provide temperature, humidity, and carbon dioxide during cell development. Incubators are of vital importance in biomedical, pharmaceutical, and clinical science, including tissue engineering, drug discovery, and microbial research.

Quick Stats for Carbon Dioxide Incubators Market

• Industry Value (2025): USD 384.9 Million
• Projected Value (2035): USD 983.3 Million
• Forecast CAGR (2025 to 2035): 8.9%
• Leading Segment (2025): Water Jacketed CO2 Incubators (35% Market Share)
• Growing Country (2025-2035): China (9.6% CAGR)
• Key Players: 3 PHC Holdings Corporation, Thermo Fisher Scientific, Eppendorf AG, Sheldon Manufacturing Inc., and BINDER GmbH

What are the drivers of the carbon dioxide incubators market?

Demand for CO₂ incubators is mainly because of the increasing need for a controlled environment in cell culture-based applications, especially drug discovery and biotechnology. The increase in chronic diseases like cancer has triggered the demand for cell-based therapies, and thus CO₂ incubators are used in research and clinical applications.

Another driver is the expansion of research on stem cells and regeneration. The market is seeing increased demand for incubation systems that deliver optimal temperature, humidity, and CO₂ levels, as researchers continue to explore cell-based therapies for repairing organs and treating degenerative diseases. This has led to technological enhancements in incubators, including infrared CO₂ sensing, antimicrobial surfaces, and improved contamination control features to support reliable and efficient performance.

The broader use of laboratory automation and artificial intelligence-monitoring systems is making CO₂ incubator operation more streamlined, efficient, and accurate. Modern incubators offer real-time monitoring, remote access, and increased security that enables consistency of conditions for fragile cell cultures. The technology is also well suited for high-throughput research and massive bio-manufacturing.

Apart from this, the increasing focus on targeted therapy and genomic research is fueling the demand for CO₂ incubators in pharmaceutical research facilities. Controlled environment development for cell culture specific to patients is of utmost significance while testing and developing drugs, and is hence creating market demand.

What are the regional trends of the carbon dioxide incubators market?

North America is a leading market for CO₂ incubators because of the strong pharma and biotech industry. With the top-quality research facilities, high healthcare spending, and substantial investment in cell therapy and regenerative medicine, the majority of growth drivers are constrained.

The U.S. market leads with ongoing bioprocessing and cell culture technology expansion. In addition to this, the stringent government regulations by the FDA and other organizations fuel demand for quality incubation solutions.

Europe is another key market, and biopharmaceuticals and research institutions have a greater need for the same. U.K., France, and Germany are leading the advancements in biotechnology, which sustains demand for high-performance incubation systems.

Government grants and joint initiatives from academic research facilities and industry companies also sustain the market drive. Investment in regenerative medicine and cancer research is also on the rise, and it's leading to broader adoption of CO₂ incubators.

Asia-Pacific is experiencing notable growth with additional biopharmaceutical units being set up in India, China, and Japan. State-funded biotech R&D of healthcare infrastructure is driving market growth. Higher investment in stem cell research and growing contract research organizations (CROs) are augmenting the demand for CO₂ incubators in the Asia-Pacific region. Greater awareness and acceptance among developing economies of cell-based therapy are also further driving the market.

What are the challenges and restraining factors of the carbon dioxide incubators market?

Market growth still dominates despite having some setbacks. The main restraint to advanced CO₂ incubators is the high price, and which prevents small research centers and labs with limited financial resources. Low maintenance requirements, such as regular surface cleaning, inner device cleaning, and keeping them clean when handling, are some expenditure requirements that prevent slowing down the growth of markets.

Another significant constraint is the risk of contamination under cell culture conditions. Even with advanced contamination control technology, maintaining a sterile environment is challenging. Equipment failure, power outages, or operational errors can result in loss of cell cultures, which affects research outcomes and increases the cost for end users.

Regulatory compliance is also a constraint in the market. The companies must undergo intense quality and safety inspections as mandated by institutions like the FDA, European Medicines Agency (EMA), and others. Good Manufacturing Practices (GMP) and Good Laboratory Practices (GLP) compliance rules often extend the process of developing products and delay market entry.

Also, emerging technologies such as organ-on-chip technologies and microfluidic cell culture systems pose substitution threats to the traditional CO₂ incubators. The technologies have improved control over the microenvironments that are set to reduce the necessity of applying traditional incubation processes.

Despite these limitations, the market is expected to maintain forward momentum, supported by continued technological development and increasing research activity in cell culture. Smart monitoring systems, enhanced contamination control practices, and energy-efficient designs will ensure future growth in the carbon dioxide incubators industry. The demand for reliable cell culture solutions across research and industrial sectors is anticipated to support market expansion through 2035.

Country-Wise Outlook

Technology-driven growth in U.S. CO₂ incubator market fueled by advanced cell culture demand

The U.S. CO₂ incubator market is growing due to the increasing demand for cell culture applications in biotechnology, pharma, and clinical research. Availability of developed life sciences and healthcare infrastructure and high R&D spending are driving the market growth. Higher regulatory requirements and the addition of newer technologies, including real-time monitored, self-adjusting CO₂ incubators with contamination control, are also influencing competitive dynamics.

Demand is being driven by expansion in regenerative medicine, stem cell therapy, and precision medicine for high-performance CO₂ incubators. Environmentally friendly, cost-efficient incubators are also becoming increasingly popular, catering to regulatory and institutional needs for environmentally friendly laboratory equipment.

China’s CO₂ incubator market accelerates with biotech investments and green lab innovations

The Chinese CO₂ incubators industry is experiencing growth due to a high level of investment in the field of biotechnology, state support of scientific research, and growing production of pharmaceuticals. The local production of high-tech laboratory and medical equipment, including CO₂ incubators, has also been boosted by China’s domestic production strategy, Made in China 2025.

Growth in conducting scientific and clinical research studies, propelled by increasing investments and collaborations, is driving market penetration. Its peak market demand also aids China's progress towards intelligent research labs and smart hospitals. Economical and green incubators with low power requirements are also popular, propelled by controlled emission requirements and green necessities.  

Compact and cost-efficient incubators gain momentum in Indian diagnostic labs

Demand for CO₂ incubators in India is increasing with the growth of biotechnology research, drug R&D spending, and the expansion of diagnostic and healthcare laboratories. Government policies like "Make in India" and tax concessions to produce medical devices are persuading local production and decreasing dependence on imports.

Tertiary care center establishment, increased clinical trials, and innovative biotech start-ups also drive the demand for the market. Low-cost and compact CO₂ incubators that small and medium-sized laboratories can use are gaining interest. In addition, the promotion of a clean environment and incubation is driving the use of technologically advanced incubators.

Category-Wise Analysis

Above 200L CO₂ incubators gain demand in high-volume cell culture and regenerative medicine

The CO₂ incubator market is growing with increased demand for the above 200-litre category as it is well-suited for large-scale research and biopharmaceutical applications. Large-capacity incubators are used extensively in cell therapy, tissue engineering, and industrial microbiology where the cell culture is performed at a large scale.   

As there is increasing R&D in vaccine production, biopharmaceuticals, and regenerative medicine, these incubators that have the ability to provide a batch of culture plates under the same environmental conditions are required by the labs. Such incubators provide aseptic conditions for cell culture using state-of-the-art temperature control mechanisms, HEPA filtration, and UV sterilization.

Additional gene therapy trials and stem cell work are also stimulating market demand. Pharma research, biologics, and customized medicine also drive adoption. Facilities are upgrading incubators with cloud data recording, auto-monitoring, and antimicrobial surfaces to address demanding laboratory requirements. With growing life sciences research, the above 200-litre CO₂ incubator segment is expected to expand considerably over the coming years.

Stable, contamination-free environments drive growth in water jacketed CO₂ incubators

Water jacketed CO₂ incubators take the lead with enhanced temperature stability and uniform heating, which is highly critical in applications involving delicate cell cultures. In contrast to direct heat models, the incubators incorporate a water chamber to handle heat fluctuation for offering accurate conditions in stem cell studies, regenerative medicine, and vaccine research.

The pharmaceutical and biotechnology sectors are very keen on advanced cell-based research and therefore the demand for stable CO₂ incubators is greater. Besides that, further investment in cancer research is fueling the demand since cancer cells need to be incubated under stringent conditions in order to conduct research on them.

Water jacket design ensures there are minimal opportunities for overheating and provides the same conditions regardless of the power fluctuations, and is in heavy demand in critical research. Manufacturers are also making it less possible to be contaminated by using antimicrobial copper touch surfaces, HEPA filters, and auto-sterilization. With increasing regulatory demands on cell culture conditions, water jacket CO₂ incubators will be the choice of research laboratories.

Precision-controlled incubation systems vital for embryo viability in IVF

In vitro fertilization (IVF) is witnessing steady growth as a result of increased rates of infertility worldwide and utilization of assisted reproductive technologies (ART). CO₂ incubators cannot be avoided in IVF centers and fertility centers, creating ideal conditions for gamete, embryo, and blastocyst development. They offer precise CO₂, humidity, and temperature control to ensure a stable condition necessary for embryonic viability. An increase in the application of time-lapse imaging incubators allows for real-time observation of embryos without breaking the culture conditions and results in augmented IVF outcomes.

Increased familiarity and spread of fertility tourism within developing economies further fuel demand for the use of CO₂ incubators in IVF treatment. Insurance coverage for fertility treatment and government subsidization are also driving the market growth. Micro-environment monitoring and high-performance tri-gas controlled (CO₂, O₂, N₂) CO₂ incubators are now industry standard and hence part of reproductive medicine today.

Competitive Analysis

The growth in carbon dioxide incubators market is escalating due to the usage in cell culture research, regenerative medicine, and pharmaceutical research applications is contributing to the competitive nature of the market. Some of the distinguishing features between companies are the precision temperature and CO₂ control, prevention of contamination as well as energy efficiency.

There is increased use of smart monitoring systems, HEPA filtration filters, and automation processes in the market to enhance the efficiency and reliability of the labs. Innovation with the product, strategic acquisitions, and global distribution channels are in the hands of major players.

Key players in the carbon dioxide incubators industry include PHC Holdings Corporation, Thermo Fisher Scientific, Eppendorf AG, Sheldon Manufacturing Inc., BINDER GmbH, Memmert GmbH Co.KG, Bellco Glass Inc., LEEC Ltd, Shanghai Boxun Medical Biological Instrument Corp., and NuAire.

Recent Developments

• In October 2024, Eppendorf AG introduced the CellXpert® CS220, the first CO₂ incubator shaker with an integrated 180 °C sterilization routine. This innovative device enhances mammalian shake flask culture projects by addressing contamination risks from viruses and Mycoplasma, offering higher flask capacity and improved cleanability for cell cultivation.
• In June 2024, Thermo Fisher Scientific launched the Thermo Scientific™ Heracell™ VIOS™ 250i AxD CO₂ Incubators, designed for fully automated laboratories in cell therapy production. Featuring patent-pending automated door control, these incubators enhance workflow efficiency while ensuring advanced contamination control and optimal cell growth conditions for high-quality standards.

Fact.MR has provided detailed information about the price points of key manufacturers of the Carbon Dioxide Incubators Market positioned across regions, sales growth, production capacity, and speculative technological expansion, in the recently published report.

Methodology and Industry Tracking Approach

The global CO₂ incubators market 2025 report was elaborated after surveying more than 12,000 hours with more than 30 countries surveyed with professionals specializing in biotechnology research, laboratory managers, clinical scientists, medical device engineers, and regulatory compliance officers.

The study program ran between July 2024 and June 2025, and the research was conducted using a validated questionnaire that was structured to evaluate the performance and role of CO 2 incubators in all areas where they are used, such as cell cultures, IVF, stem cell research, regenerative medicine, and pharma R&D.

The results were cross-checked, with more than 300 proven sources of data utilized, including regulatory systems abroad (e.g., FDA, CE, ISO), technical manuals, equipment benchmarking reports and white papers of industry leaders. Regression-based forecasting methods and indexed scoring models were used to predict future market growth, technology adoption, and investment opportunities with a high degree of analytical accuracy.

With Fact.MR has been monitoring consumer behavior, product efficacy, industry trends, and market opportunities since 2018, and this report is becoming an authoritative source of information that stakeholders can rely on.

Segmentation of Carbon Dioxide Incubators Market

• By Capacity :

  • Below 100 Litres
  • 100 to 200 Litres
  • Above 200 Litres

• By Product :

  • Water Jacketed CO₂ Incubators
  • Air Jacketed CO₂ Incubators
  • Direct Heat CO₂ Incubators

• By Application :

  • Laboratory Research & Clinical Applications
  • In Vitro Fertilization
  • Others

• By Region :

  • North America
  • Latin America
  • Western Europe
  • Eastern Europe
  • East Asia
  • South Asia & Pacific
  • Middle East & Africa