Aptamers Market

Aptamer Producers Cashing in on High Demand from Food and Beverage Sector

Advent of the chemical modification process to increase the nuclease resistance of aptamers, and, in turn, enhance their therapeutic properties creates opportunities galore for players in the aptamer market.

This has also lead to steady increase in the demand for aptamers and related products from research institutions. Ongoing research & development activities have led to the adoption of aptamers, both, as drugs and drug-carriers, and their application as diagnostics tools is opening new growth avenues for manufacturers.

In future, the application of aptamers will meet an expanded scope in the food and beverage industry as biosensors to ensure the quality of products.

On the back of such favourable factors, a recently published study by Fact.MR opines that, the aptamer market would progress at an impressive pace, at a CAGR of 21% during the forecast period (2020-2025).

Aptamer Technology Lacks Proper Dissemination of Information, Leading to Limited Adoption

Being a relatively novel technology, some characteristics of aptamers are still unexplored, which poses a technical challenge for manufacturers.

Low molecular weight of these molecules causes rapid degradation of biological media and blood, which needs proper synthesis to keep unwanted characteristics of aptamers in check.

However, manufacturers choose to avoid using these molecules, on the backdrop of lack of knowledge regarding aptamers and lack of technical expertise.

Moreover, aptamers are found to have a short half-life (within the range of minutes to hours), which impedes the practical application of these molecules in the development of therapeutics.

SELEX Remains the Gold Standard Selection Technique in Aptamer Market

Continuous advancements in selection technique remain a critical lever to the growth of the aptamer market. The conventional Systemic Evolution of Ligands by Exponential Enrichment (SELEX) technique included lengthy iterative steps, which would delay probe selection and further slowdown the selection process.

To offset this challenge, a key player-SOMALOGIC, INC.-introduced SOMAmer, which is a next-gen selection platform with the competency to extract high-quality aptamers for numerous applications.

Given the progressive development, the SELEX technique is deemed suitable for the selection of aptamers. In 2020, the SELEX technique is estimated to account for 80% of the total market share, on the back of its competency to determine the binding site of a protein on RNA.

Additionally, with time-efficiency being the key to achieve better traction in the healthcare industry, numerous research organizations are investing in the development of cost- and time-effective selection approaches.

In the future, the Magnetic-assisted Rapid Aptamer Selection (MARAS) and FRELEX methods are projected to witness high adoption, on account of their simplified enzymatic steps, which fast-tracks the selection process.

Lack of Universal Regulatory Guidelines Leading to Low Level of Awareness

Unlike other drugs and diagnostic tools, aptamers lack a standard regulatory standard for quality and safety. However, the approval process remains highly stringent in developed regions such as North America and Europe.

For instance, there is a tedious documentation process for starting clinical trials for aptamers in Europe, but absence of oligonucleotide specific guidelines to validate their general quality requirements.

On the other side of the world, in Asia Pacific and the Middle East & Africa, there is a low level of awareness regarding these molecules.

On the backdrop of lack of universal regulatory norms, the penetration of aptamers in these regions is projected to remain limited to some extent.

Intense Research in North American Aptamer Market Catalysing its Growth

North America’s lead in the aptamer market is fuelled by the early-bird’s advantage of advanced technology that manufacturers are receiving in the region.

Continuous progress in the research & development of therapeutics and diagnostics equipment undertaken by research institutes is projected to demand an ongoing supply of aptamers, thereby creating opportunities for players in the North American aptamer market space.

In Europe, there has been a marked spike in awareness regarding health issues, which is imparting strength to the demand for effective diagnostic tools to detect infectious and chronic diseases.

This will create opportunities for the aptamer market in Europe from the biotechnology industry.

Growth of the aptamer market in Asia Pacific is projected to remain significantly driven by collaborative efforts taken by players in developed regions to foray into the untapped market.

Knowledge sharing of technologies and pharmaceutical know-hows among established players of North America and Europe and prominent/local players of Asia Pacific is projected to pave way for expansion of the aptamer market during the forecast period.

Aptamer Market – Assessment of Key Segments

With an aim to offer granular level insights into the aptamer market, authors of the report have segmented the landscape on the basis of application, selection technique, material, and region. This global research report also analysis the incremental opportunity available in the aptamer market during the forecast period. Key segments of the aptamer market include:

This detailed guide, based on the latest market movement, ensures that only precise information reaches stakeholders, so as to help them gain an upper hand over their competitors in the global aptamer market. This exclusive guide offers crucial information about the current trends, pipeline drugs, unmet drugs, future scope, and government regulations for the aptamer market.

Aptamer Market – Scope of the Study

Fact.MR, in its exclusive research report on the aptamer market, highlights actionable insights and winning imperatives for stakeholders.

This comprehensive study unfolds rare and distinguished intelligence regarding impactful dynamics, which directly or indirectly are expected to influence the growth of the aptamer market during the forecast period (2020-2025).

With the help of crucial insights discussed in this study, stakeholders will gain a thorough idea regarding the growth trajectory of the aptamer market.

This comprehensive study offers incisive data regarding the drivers, threats, restraints, and opportunities present in the aptamer market.

The study also recalibrates the impact of each of these dynamics to estimate the size of the aptamer market for the given period.

Authors of the report have taken ample care to measure and include the relevance and impact of microeconomic as well as macroeconomic factors that hold potential to influence the growth of the aptamer market during the forecast period.

The global study on the aptamer market includes Porter’s Five Forces analysis, in order to present the buyer’s and supplier’s power in the aptamer landscape.

In addition, the analysis also discusses the threat of substitutes and new entrants, which provides a brief idea regarding the future growth course of the aptamer market.

The study offers crucial information about global, regional, and local players operating in the aptamer market, along with their estimated market share. Market share has been estimated in terms of value (US$ Mn).

Besides providing key information regarding the concentration of leading, prominent, and local players, the study also aims at equipping stakeholders with the best of information regarding the winning strategies, recent developments, and financials.

The comprehensive study highlights key players operating in the aptamer market, which includes AM Biotech, CD Genomics, Aptagen, LLC, Base Pair Biotechnologies, Aptamer Group, Aptamer Sciences, Inc., TriLink Bio Technologies, LLC, NewVentures Biotechnology, Inc., Aptus Biotech, and NAXXON Pharma.

Aptamer Market – Research Methodology

Research undertaken by seasoned analysts at Fact.MR consists of a systematic approach.

A combination of the bottom-up and top-down approach is leveraged to estimate the size of the aptamer market. Besides this, primary and secondary research is carried out through credible sources to gain crucial insights into the aptamer market.

For conducting primary research, interviews and discussions were carried out with industry experts, key opinion leaders, vendors, and distributors.

Besides these, respondents also include CEOs, presidents, directors, chairmen, vice presidents, marketing managers, suppliers, distributors, and chief medical officers, among others.

This helps in assessing the demand-supply gap prevailing in the aptamer market. In order to conduct secondary research, marketing collaterals, company websites, industry associations, and government statistics were studied.

In addition to this, reports as well as content pieces published by credible sources, such as company annual reports, investor presentations, and SEC-Filings, were studied.

Also, governmental and public portals such as International Journal of Molecular Science, Biomed Research International, Journal of Pharmacology and Experimental Therapeutics, and Journal of the American Chemical Society were referred to, to gain crucial information regarding key players in the aptamer market. Insights obtained through primary and secondary research are then authenticated with the data triangulation method.