Non-hormonal steroid modulators are the biological ligands or compound that binds to the receptor as agonist or antagonist to alter the biological reaction associated with the receptors. Beside their steroidal nature, non-hormonal steroid modulators don’t bind hormone receptors. World Health Organization (WHO), one in every 3000 inpidual is affected with Muscular dystrophy, over 9.6 million lives have been claimed by cancer and prevalence of arthritis 0.3% and 1%, with higher prevalence in females. Non-hormonal steroid modulators serve for modulating various biological receptors or cell signalling molecules to modulate their function in various disease prognosis including cancer drug-resistance, arthritis, muscular dystrophies and several other autoimmune and inflammatory diseases. In cancer, the non-hormonal steroid modulators such as RU49953 plays a primary role in the drug efflux or drug resistances and several non-hormonal steroid modulators modulate the NF-κB to alleviate arthritis and muscular dystrophy. Global non-hormonal steroid modulators are expected to flourish in future with the elevation of the ongoing research and studies with government aids, also the clinical trial of several non-hormonal steroid modulators promises a robust future growth of its market. Coronavirus pandemic is anticipated to support the global non-hormonal steroid modulators, as the steroids, in general, have been seen to cure the coronavirus-infection, therefore more research and clinical studies can be expected to show the positive impact of non-hormonal steroid modulators to treatment coronavirus.
Non-Hormonal Steroid Modulators Market: Drivers and Restraints
The growth of the global non-hormonal steroid modulators is driven by the active researches that dwell into the treatment of cancer drug-resistance, autoimmune and inflammatory diseases such as arthritis and muscular dystrophy with the use of non-hormonal steroid modulators, along with the support of government funding. The ongoing clinical trials and the major key players are dwelling into the development of novel non-hormonal steroid modulators for the treatment of diseases are further accelerating the market growth. However, the adverse reactions of non-hormonal steroid modulators and the stringent regulatory system decelerate the growth pace of global non-hormonal steroid modulators market. Although, the global non-hormonal steroid modulators market is anticipated to grow in future with the escalating research and rigorous progress of clinical trials to.
Non-Hormonal Steroid Modulators Market: Segmentation
The global non-hormonal steroid modulators are segmented into by modulator type, indication and region.
By modulator type, the global non-hormonal steroid modulators are further segmented into:
- Non-Hormonal Steroid NF-κB Modulator
By indication, the global non-hormonal steroid modulators are further segmented into:
- Muscular Dystrophy
- Cancer Drug-Resistance (Drug Efflux)
Non-Hormonal Steroid Modulators Market: Overview
The global non-hormonal steroid modulators market is anticipated to grow in future with the progressing researches and clinical trials to treat cancer drug-resistance, arthritis and muscular dystrophy. By modulator type, the segment is pided into RU49953 and non-hormonal steroid NF-κB modulator. RU49953 is an estradiol derivative that chemo-sensitizes MDR-1 P-glycoprotein which plays secretory and protective roles against steroid hormones. RU49953 possess improved hydrophobicity leading to intracellular accumulation of drugs and thus helps in curbing the anti-cancer drug efflux from cells. Non-hormonal steroid NF-κB modulator was developed to cure arthritis and muscular dystrophy, by modulating the pro-inflammatory actions of NF-κB. By indication, the segment is pided into arthritis, muscular dystrophy and cancer-drug resistances.
Non-Hormonal Steroid Modulators Market: Regional Outlook
Europe dominates the global non-hormonal steroid modulators market with its leading research studies and clinical trials, the European market is pushed by the high prevalence of arthritis in this region, and special attention of European Commission towards muscular dystrophy therapies. North America holds the second-largest non-hormonal steroid modulators market with its active R&D activities, key players and non-hormonal steroid modulators patent claimed for muscular dystrophy and arthritis. Asia-Pacific non-hormonal steroid modulators are expected to bloom in future, with the massive burden of arthritis, escalating research and improving healthcare, along with the support of government funding. Latin America non-hormonal steroid modulator market is expected to grow moderately with improving research and healthcare. The Middle East & Africa non-hormonal steroid modulators market is expected to remain stagnant due to the under-developed medical healthcare and R&D infrastructure. Latin America is expected to grow at a moderate rate with the gradual elevation of the research and technology. The Middle East & Africa is expected to have a stagnant growth due to the under-developed research infrastructure.
Non-Hormonal Steroid Modulators Market: Key Players
The key player of the non-hormonal steroid modulators market is ReveraGen Biopharma Inc.
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