Casein Glycomacropeptide Market

Casein Glycomacropeptide (CGMP) Market Size and Share Forecast Outlook 2025 to 2035

The global casein glycomacropeptide (CGMP) market is forecast to reach USD 215.9 million by 2035, up from USD 126.4 million in 2025. During the forecast period, the industry is projected to register at a CAGR of 5.5%.

The increasing demand for protein-rich dietary supplements that contain low levels of phenylalanine especially for the dietary treatment of phenylketonuria (PKU) is contributing to the market for CGMP.

In general, use in functional foods and beverages is increasing as awareness of its prebiotic properties and benefits for digestive health increase. The new applications in medical nutrition and sports nutrition products are contributing to the market growth.

Quick Stats of Casein Glycomacropeptide (CGMP) Market

• Casein Glycomacropeptide (CGMP) Market Size (2025): USD 126.4 million
• Projected Casein Glycomacropeptide (CGMP) Market Size (2035): USD 215.9 million
• Forecast CAGR of Casein Glycomacropeptide (CGMP) Market (2025 to 2035): 5.5%
• Leading Application Segment of Casein Glycomacropeptide (CGMP) Market: Infant Formula
• Leading Source Segment of Casein Glycomacropeptide (CGMP) Market: Bovine
• Key Growth Regions of Casein Glycomacropeptide (CGMP) Market: United States, China, Japan
• Prominent Players in the Casein Glycomacropeptide (CGMP) Market: Arla Food Ingredients, GL Biochem Ltd., S A Pharmachem Pvt. Ltd., Agropur Ingredients, and American Dairy Products Institute.

Metric	Value
Industry Size (2025E)	USD 126.4 million
Industry Size (2035F)	USD 215.9 million
CAGR (2025-2035)	5.5%

The casein glycomacropeptide (CGMP) market is expected to expand at a CAGR of 5.5% between 2025 and 2035, indicating a steady and reliable upward trajectory over the forecast period.

This rate of growth suggests that demand will consistently increase year after year, supported by a broadening scope of applications and the growing recognition of CGMP as a valuable functional ingredient. The steady pace reflects a balanced market expansion, avoiding volatility while building a strong foundation for long-term adoption.

A primary factor driving this growth is the clinical importance of CGMP in medical nutrition, particularly for managing phenylketonuria (PKU). With rising awareness of metabolic disorders and improvements in healthcare access, CGMP-based dietary solutions are becoming an essential component of specialized nutrition.

In parallel, the compound is increasingly utilized in functional foods, sports nutrition, and gut health products, where its bioactive properties and amino acid profile distinguish it from conventional proteins. These multiple end-use areas are expected to provide a stable growth stream throughout the forecast horizon.

On the supply side, advancements in separation and purification technologies are improving the efficiency of CGMP production. While extraction processes remain complex, innovations in enzymatic and membrane filtration methods are gradually enhancing cost-effectiveness.

The profit pool remains strongest in specialized medical nutrition segments, where clinical demand ensures higher margins. At the same time, functional food and supplement manufacturers are beginning to integrate CGMP into mainstream consumer offerings, which expands the base of adoption beyond therapeutic niches.

Despite these promising drivers, certain challenges limit growth. Production remains cost-intensive compared with conventional whey proteins, making pricing a barrier for widespread consumption in emerging economies. Regulatory requirements also influence market expansion, as CGMP must comply with strict standards for clinical and functional use. In addition, product positioning as a premium protein source can constrain accessibility to budget-conscious buyers.

The projected CAGR of 5.5% points to consistent year-on-year growth for the CGMP market. While clinical nutrition will remain its anchor, the ability to expand into wellness, sports, and functional foods will define future opportunities. Companies that optimize production efficiency and balance premium positioning with broader accessibility are likely to benefit the most from this steady market trajectory.

Key Casein Glycomacropeptide (CGMP) Market Dynamics Analyzed

The casein glycomacropeptide (CGMP) market is projected to grow at a steady pace, supported by its expanding role in medical nutrition, functional foods, and sports applications. Growth momentum is shaped by strong demand for low-phenylalanine proteins, rising consumer focus on gut health, and wider distribution through e-commerce.

At the same time, the industry faces hurdles such as high production costs, limited awareness in developing markets, and regulatory compliance pressures. Together, these drivers and challenges define the balance between opportunity and restraint in the CGMP market’s evolution.

Medical Nutrition and PKU Management Stimulating Demand

A primary growth driver for CGMP is its role in medical nutrition, particularly as a treatment for phenylketonuria (PKU). Due to its low phenylalanine content, CGMP offers a safe protein source for PKU patients, making it an indispensable ingredient in specialized dietary formulations.

The demand from healthcare professionals and specialty product producers is expected to rise steadily, as awareness of PKU management continues to improve globally. This clinical relevance secures CGMP’s position as a high-value protein derivative.

Applications in Gut Health and Functional Foods

Growing consumer focus on gut health and immunity is creating opportunities for CGMP as a functional ingredient. With its prebiotic properties, CGMP supports the growth of beneficial gut bacteria, enhancing digestive health and immunity.

This aligns with the rising preference for clean-label proteins and natural bioactive compounds. Functional food and beverage manufacturers are integrating CGMP into their products to cater to health-conscious consumers, reinforcing its presence in mainstream nutrition.

Rising Application in Sports Nutrition Products

Athletes and active lifestyle consumers are increasingly drawn to CGMP for its high digestibility and amino acid profile, which support muscle recovery and performance.

This trend is encouraging sports nutrition brands to adopt CGMP as a differentiating protein source compared to conventional whey or casein. With the broader movement toward premium protein ingredients, CGMP is positioned as a performance-enhancing solution with added clinical credibility.

Technological Advances and Market Access

Advances in dairy processing and filtration technology are improving the purity, yield, and cost efficiency of CGMP extraction. These technological improvements are making large-scale production more viable.

At the same time, the rise of e-commerce and retail health platforms is widening accessibility, enabling CGMP-based products to reach international markets more easily. This expanded distribution channel enhances awareness while driving product adoption across diverse consumer groups.

High Production Costs

The most significant challenge for CGMP adoption lies in its complex extraction and purification process, which results in higher production costs compared with other protein sources.

These costs translate into higher product prices, limiting accessibility for price-sensitive consumers and reducing competitiveness against cheaper alternatives such as whey protein or soy protein.

Limited Awareness and Market Recognition

Despite proven benefits in PKU management, gut health, and sports nutrition, overall consumer awareness of CGMP remains limited, particularly in emerging markets.

Many potential users remain unaware of its advantages, which restricts market penetration. Education campaigns and clinical endorsements will be critical to overcoming this barrier and unlocking broader demand.

Regulatory and Compliance Barriers

Strict food safety, labeling, and medical nutrition regulations present another major obstacle. Manufacturers are required to invest substantial resources to meet compliance standards across multiple countries.

These regulatory complexities slow product launches, increase operational costs, and create uneven adoption between developed and developing regions, thereby limiting overall growth potential.

What are the Regional Trends of Casein Glycomacropeptide (CGMP) Market?

The North American Region is the greatest consumer of medical nutrition products, especially for the treatment of PKU, causing the Casein Glycomacropeptide (CGMP) market to escalate. Modern dietary supplement businesses and a high knowledge base for medical professionals are contributing to this growth. The area also benefits from large distribution chains and a flourishing sports nutrition enterprise.

The increase in specialist medicinal foods and dietary restrictions in Europe is increasing demand. Research and product innovation in nutrition for PKU is spearheaded by countries like Germany, the UK, and France, and is further supported by increasing interest from consumers for functional foods and products high in prebiotic ingredients.

Increasing health awareness, disposable incomes and investor interest in developing dairy processing companies are fueling the rapid growth of the Asia-Pacific region. Countries such as China, Japan and Australia are beginning to adopt CGMP for areas of medicinal diet, sports nutrition, and functional beverages. The rise of e-commerce is improving the access of CGMP-based products for consumers across the region.

Country-Wise Outlook

Countries	CAGR (2025 to 2035)
United States	5.8%
China	6.5%
Japan	5.2%

U.S. Casein Glycomacropeptide (CGMP) Market is Experiencing Strong Growth

The Casein Glycomacropeptide (CGMP) (CGMP) market in the United States is growing due to increased demand from medical nutrition products developed specifically for patients with phenylketonuria (PKU). The high levels of awareness of patients and health professionals facilitates the use of CGMP in specialty dietary supplements, and demand continues to be stimulated by health care and government programs that aim to promote the management of rare disease.

The rapidly growing sports nutrition market in the US, where athletes and fitness consumers demand high-quality, bioavailable protein for performance support and recovery, is also a factor driving demand for CGMP. Health-conscious consumers also appreciate CGMP for its naturally occurring bioactive properties and benefits for digestive health.

Improvements in dairy processing technology have improved the purity and recovery efficiency of CGMP, creating a financial and commercial feasibility for CGMP. The growth of e-commerce channels and established retail channels has also increased visibility and access to CGMP products across the US. Clean label and functional protein products are growing rapidly, providing CGMP with a competitive advantage in the US market.

China Casein Glycomacropeptide (CGMP) (CGMP) Market is Expanding Rapidly Due to Increasing Health Awareness

The China Casein Glycomacropeptide (CGMP) (CGMP) market is experiencing rapid growth as a result of health consciousness and peoples' desire for its quality protein source. An increased incidence of CGMP in medical nutrition has given way to its use in battling and diagnosing phenylketonuria (PKU). Also, government support in funding rare disease therapy has been helpful in support of CGMP market development.

Furthermore, with the growing of sports and fitness within the country, a higher level of demand is being created for CGMP products in performance supplements. The higher level of awareness of CGMP complemented in the demand is being driven by athletes and health-conscious individuals. The presence of an easy-to-digest, low allergen, gut-health promoting protein source has contributed to growing CGMP acceptance. Compliance with regulatory standards has further paved the way for acceptance of CGMP among producers of functional foods and beverages.

Fortunately, due to improvements made in CGMP manufacturing in China through dairy processing, there is also less reliance on imported CGMP. Developments for commercial CGMP products through modern retail and e-commerce are also seeing higher volumes of availability in the marketplace along with improvements to supply chain methods. All of these factors are serving to create growth momentum for CGMP in China.

Japan’s Casein Glycomacropeptide (CGMP) (CGMP) Demand is Driven by its Strong Application in Medical Nutrition

In Japan, the availability of Casein Glycomacropeptide (CGMP) (CGMP) is greatly affected by its widespread application in medical nutrition to treat phenylketonuria (PKU). Japan has an established health system and awareness of rare conditions that allows for timely detection and treatment of individuals with PKU. This allows for continued, sustained demand for CGMP foodstuffs.

Due to an aging population, there is huge growth in interest in nutrient sources with robust digestibility properties that promote gut health. CGMP is low allergenicity, has prebiotic properties, and is an excellent option for senior nutrition, and behavioral functional food and beverage companies can use features like these to promote product development to health-oriented consumers.

Japan synthesizes CGMP with very high purity because a standard dairy processing sector that utilised strict quality assurance practices existed -- CGMP is a dairy-based product. There are multiple retail types (pharmacy channels, health food stores, and online) that create available CGMP options for consumers. These circumstances create a sustained and growing consumer demand for CGMP food products in Japan.

Category-wise Analysis

Infant Formula in the Casein Glycomacropeptide (CGMP) (CGMP) Market is Growing Steadily

The infant formula segment continues to grow, owing to CGMP's low phenylalanine and nutritional quality, it is a choice for newborns with phenylketonuria (PKU), making it appealing to parents and healthcare practitioners as a safe and highly digestible protein option in specialized infant foods.

Advancements in dairy technology have enabled manufacturers to invest in higher-end specialty formulas containing CGMP, due to trends in early-life nutrition and functional proteins. The growing acceptance of CGMP as an ingredient for infant nutrition products and in developed markets like the U.S., Europe, and Japan, has both increased CGMP adoption and created a stable growing region for this ingredient.

The heightened availability of functional proteins that enhance immune function, gut health, and human performance represents a major shift in potential growth area for CGMP in adult nutrition. Given that CGMP has a high digestibility profile and prebiotic properties it can be included as a source of protein in geriatric nutrition or for people with restricting diets. CGMP supplements may also be more readily promoted in lifestyle treatment plans for individuals managing chronic diseases and for more active fitness participants.

It is used in medical nutrition to create individualized meal plans for PKU and other metabolic disorders. As the demand for high-quality proteins from dairy in developed and developing nations continues to build along with the clean-label trend, there is consistent ongoing growth in adult nutritional applications around the world.

Bovine-Derived CGMP Dominates the Market

Bovine-sourced CGMP is the most widely used form of CGMP in the marketplace, arguably because of easy access, low cost and processors are already well established. Nations that are strong in dairy enterprises advocate for bovine CGMP on the world stage. Essentially, and reliable, high yielding, CGMP is, by far and away, the preferred source for functional foods, sports/athletic and medical foods/nutrition products.

Bovine milk itself is being fractionated allowing for increased purity and efficiency in CGMP extraction. The substantial market for CGMP in food, pharmaceutical and nutraceuticals, suggest CGMP from bovine will continue to be the overwhelming source and as it becomes more accepted will extend into other industries through trading and exports.

An increasing number of consumers, both allergic to milk and sensitive to cow's milk, are using caprine (goat) CGMP in their diet. Due to smaller fat globules and better protein characteristics that make it easier to digest, caprine CGMP can be used in an infant formula, senior nutrition, and for certain clinical indications. Caprine CGMP is in growth mode, driven by niche but increasing market demand from goat milk products in the premium and health category.

A shorter supply on goat milk, as with all specialty products will enable producers to benefit from, as they are investing in new technology to improve extraction efficiency even when the yield is lower than cow milk. The market for more specialty and allergenic dairy foods should warrant these opportunities for caprine CGMP in international niche markets going forward.

Powdered CGMP is the Most Widely Used Form Due to its Versatility, Long Shelf Life, and Ease of Incorporation into Various Products

Powdered CGMP is the form of CGMP most frequently utilized. Manufacturers prefer powdered CGMP due to its versatility, shelf stability and compatibility with other products. The stability of powdered products is appealing for manufacturers of sports nutrition products, functional foods, and dietary supplements.

The flexibility of powdered CGMP allows for manufacturer of specific medicinal diets for PKU patients and other patients requiring closer concentration of a nutrient. Powdered CGMP is lightweight and does not require refrigeration/freezing making it likely the format of choice in international business.

Powdered CGMP continues to be developed as the demand for food and pharmaceutical usage continues to grow. Companies are trying to develop better drying technology to keep up with demand. The trend of clean label continues to make powdered CGMP available at a more competitive price worldwide utilizing health-food brands.

Liquid CGMP is being utilized in sports recovery formulations, and in some cases including medicated feeds and ready-to-drink nutritional beverages. The quick absorption and easy digestibility made this less process amenable to a fast-paced world and those requiring therapeutic nutrition or sports nutrition with performance enhancing or unique products. Liquid CGMP continues to have a place in clinical settings for patients with PKU who require fast and precise nutrition.

The increasing shelf-stable formulation and packaging developments have led to a rising cost-effectiveness of liquid CGMP. While liquid CGMP has a smaller share of the market than powder forms, its advantages and the growth of the functional beverage market suggests that it should also see a bright future, especially in developed countries with strong sports nutrition and medical markets.

Food and Beverage Manufacturers are Increasingly Incorporating CGMP into Functional Products

Functional food and beverage manufacturers have started specifically utilizing CGMP (conjugated glycerol monolaurate) in functional items such as protein bars, fortified dairy products, health focused beverages, and special medical foods. There is a high protein content, isn’t allergenic, and has prebiotic characteristics. CGMP is attractive to health and wellness formulations partly because of the desires for clean-label food, and natural protein sources, which are driving CGMP adoption into luxury food formulations.

Functional beverage manufacturers are using CGMP directly in their formulations, where the end users are consumers who are focusing on both immunity and gut health. Consumer awareness and understanding of what constitutes protein quality and functional health attributes that CGMP can provide should create explosive demand for CGMP from food and beverage manufacturers across customary and niche market sectors.

The medical indications for CGMP including metabolic disorders and PKU indicate that pharmaceutical companies are a large potential demand sector. Standardized CGMP extracts are found in medical nutrition products both over the counter and prescription. CGMP use in the pharmaceutical industry is flourishing as pharmaceutical companies are specifically focusing on managing rare diseases and medically governing nutrition therapy.

Businesses are spending money on clinical research to confirm that CGMP has therapeutic advantages beyond PKU, such as immunological and gut health support. Multiple nations' regulatory approvals are also making it possible for pharmaceutical businesses to sell CGMP-based goods, guaranteeing steady demand and setting up this industry for long-term, steady growth.

Competitive Analysis

Major participants in the Casein Glycomacropeptide (CGMP) (CGMP) market, which is moderately competitive, include companies in pharmaceuticals, dairy producers, and companies with nutritional supplements brands. The primary areas of competition in CGMP are cost-effectiveness, bioactivity, purity, and regulatory complication.

In particular to medical nutrition, companies with strong research capability and leading extraction methodology are important competitive advantages. Additionally, clinical validation and clean-label certifications and sustainability features into a premium market position.

Established companies are able to leverage strong retail distribution channels, healthcare distribution channels, and their high levels of e-commerce are also competitive advantages, while niche brands are more focused on specialist markets like functional/ hypoallergenic food. R&D spending, as a part of the competitive strategy revolves around increasing formulation innovation -whether it be powders, liquids or fortified products.

Key Players in the Market

• Arla Food Ingredients
• GL Biochem Ltd.
• S A Pharmachem Pvt. Ltd.
• Agropur Ingredients
• American Dairy Products Institute

Recent Development

• In April 2025, FSANZ, or Food Standards Australia New Zealand, has authorized the use of MFGM as a nutritional ingredient in baby formula. Once the approval has been formally accepted by the Food Ministers Meeting of Australia and New Zealand, it becomes effective.

Segmentation of Casein Glycomacropeptide (CGMP) Market

• By Application :

  • Infant Formula
  • Adult Nutrition
  • Sports Nutrition
  • Functional Foods
  • Pharmaceuticals

• By Source :

  • Bovine
  • Caprine
  • Ovine

• By Product Type :

  • Powdered CGMP
  • Liquid CGMP

• By End-User :

  • Food and Beverage Manufacturers
  • Pharmaceutical Companies
  • Dietary Supplement Manufacturers
  • Research Institutes
  • Others

• By Region :

  • North America
  • Latin America
  • Western Europe
  • Eastern Europe
  • East Asia
  • South Asia & Pacific
  • Middle East & Africa